cvd-logocvd - Molecule ID A317F

geneANO8, TMEM16H
nameAnoctamin-8
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ANO8_HUMANQ9HCE9ENSG0000007485557719Hs.590990610216

Functions and classifications

GOC:cytosolic small ribosomal subunit, C:endocytic vesicle lumen, C:extracellular region, C:haptoglobin-hemoglobin complex, C:hemoglobin complex, F:heme binding, F:iron ion binding, F:oxygen binding, F:oxygen transporter activity, P:bicarbonate transport, P:hydrogen peroxide catabolic process, P:oxidation-reduction process, P:oxygen transport, P:positive regulation of cell death, P:protein heterooligomerization, P:small molecule metabolic process
UniProtAcetylation, Alternative splicing, Cell membrane, Complete proteome, Membrane, Reference proteome, Transmembrane, Transmembrane helix
PADBCNL: channel

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19059264Homo sapiens31bloodmonocytes and T-helper cellsAtherosclerosis (Coronary Atherosclerosis)0.822<0.05Gene-array19059264
Exp21804111Mus musculus9aorta CAD (Coronary artery disease (CAD))1.235<0.05Gene-array21804111
Exp21868699aMus musculus20macrophages Atherosclerosis (Atherosclerosis)1.380<0.05Gene-array21868699
Exp21868699bMus musculus40aorta and macrophages CAD (Coronary artery disease (CAD))1.380<0.05Gene-array21868699
Exp24082102Mus musculus88heartwholeCAD (Coronary artery disease (CAD))1.435<0.05Gene-array24082102
Exp24530965Homo sapiens23bloodmononuclear cells (PBMCs)CAD (Familial Hypercholesterolemia and Coronary artery disease (CAD))0.423<0.05Gene-array24530965
Exp25835000Homo sapiens31macrophages CAD (Coronary artery disease (CAD))0.825<0.05Gene-array25835000
Exp27142736Mus musculus12liver CAD (Coronary artery disease (CAD))1.000<0.05Gene-array27142736

Compile date 02-09-2018© C/VD project