cvd-logocvd - Molecule ID A286F

geneALKBH1, ABH, ABH1
nameAlkylated DNA repair protein alkB homolog 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ALKB1_HUMANQ13686ENSG000001006018846Hs.94542605345

Functions and classifications

GOC:extracellular region, C:extracellular space, C:filopodium, C:growth cone, F:cholesterol binding, F:choline binding, F:low-density lipoprotein particle binding, F:metal ion binding, P:acute-phase response, P:aging, P:cellular response to calcium ion, P:complement activation, classical pathway, P:defense response to Gram-positive bacterium, P:negative regulation of lipid storage, P:negative regulation of macrophage derived foam cell differentiation, P:opsonization, P:positive regulation of dendrite development, P:protein polymerization, P:response to ethanol, P:response to hypoxia, P:response to lead ion, P:wound healing, C:extracellular space, F:Gram-positive bacterial cell surface binding, P:response to lead ion
UniProtComplete proteome, Dioxygenase, DNA damage, DNA repair, Iron, Lyase, Metal-binding, Mitochondrion, Multifunctional enzyme, Nucleus, Oxidoreductase, Polymorphism, Reference proteome, RNA repair
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19059264Homo sapiens31bloodmonocytes and T-helper cellsAtherosclerosis (Coronary Atherosclerosis)0.514<0.05Gene-array19059264
Exp21804111Mus musculus9aorta CAD (Coronary artery disease (CAD))1.418<0.05Gene-array21804111
Exp21868699aMus musculus20macrophages Atherosclerosis (Atherosclerosis)1.392<0.05Gene-array21868699
Exp21868699bMus musculus40aorta and macrophages CAD (Coronary artery disease (CAD))1.392<0.05Gene-array21868699
Exp24082102Mus musculus88heartwholeCAD (Coronary artery disease (CAD))1.227<0.05Gene-array24082102
Exp24530965Homo sapiens23bloodmononuclear cells (PBMCs)CAD (Familial Hypercholesterolemia and Coronary artery disease (CAD))1.490<0.05Gene-array24530965
Exp25835000Homo sapiens31macrophages CAD (Coronary artery disease (CAD))1.557<0.05Gene-array25835000
Exp27142736Mus musculus12liver CAD (Coronary artery disease (CAD))1.008<0.05Gene-array27142736

Compile date 02-09-2018© C/VD project