cvd-logocvd - Molecule ID A253F

geneADIPOR2, PAQR2
nameAdiponectin receptor protein 2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ADR2_HUMANQ86V24ENSG0000000683179602Hs.371642607946

Functions and classifications

GOC:chylomicron, C:cytosol, C:early endosome, C:endoplasmic reticulum lumen, C:high-density lipoprotein particle, C:very-low-density lipoprotein particle, F:antioxidant activity, F:cholesterol transporter activity, F:copper ion binding, F:phosphatidylcholine binding, F:phosphatidylcholine-sterol O-acyltransferase activator activity, F:protein homodimerization activity, P:cholesterol efflux, P:cholesterol homeostasis, P:cholesterol metabolic process, P:chylomicron assembly, P:chylomicron remodeling, P:high-density lipoprotein particle remodeling, P:hydrogen peroxide catabolic process, P:innate immune response in mucosa, P:leukocyte cell-cell adhesion, P:lipoprotein metabolic process, P:multicellular organismal lipid catabolic process, P:negative regulation of plasma lipoprotein particle oxidation, P:phosphatidylcholine metabolic process, P:phospholipid efflux, P:phototransduction, visible light, P:positive regulation of cholesterol esterification, P:positive regulation of fatty acid biosynthetic process, P:positive regulation of lipoprotein lipase activity, P:positive regulation of triglyceride catabolic process, P:regulation of cholesterol transport, P:regulation of intestinal cholesterol absorption, P:removal of superoxide radicals, P:response to lipid hydroperoxide, P:response to stilbenoid, P:retinoid metabolic process, P:reverse cholesterol transport, P:very-low-density lipoprotein particle remodeling, C:extracellular region, F:lipid binding, P:lipid transport, C:chylomicron, P:very-low-density lipoprotein particle remodeling
UniProtComplete proteome, Fatty acid metabolism, Lipid metabolism, Membrane, Polymorphism, Receptor, Reference proteome, Transmembrane, Transmembrane helix
PADBRCP: receptor

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19059264Homo sapiens31bloodmonocytes and T-helper cellsAtherosclerosis (Coronary Atherosclerosis)1.136<0.05Gene-array19059264
Exp21804111Mus musculus9aorta CAD (Coronary artery disease (CAD))0.738<0.05Gene-array21804111
Exp21868699aMus musculus20macrophages Atherosclerosis (Atherosclerosis)1.495<0.05Gene-array21868699
Exp21868699bMus musculus40aorta and macrophages CAD (Coronary artery disease (CAD))1.495<0.05Gene-array21868699
Exp24082102Mus musculus88heartwholeCAD (Coronary artery disease (CAD))1.740<0.05Gene-array24082102
Exp24530965Homo sapiens23bloodmononuclear cells (PBMCs)CAD (Familial Hypercholesterolemia and Coronary artery disease (CAD))0.248<0.05Gene-array24530965
Exp25835000Homo sapiens31macrophages CAD (Coronary artery disease (CAD))0.830<0.05Gene-array25835000
Exp27142736Mus musculus12liver CAD (Coronary artery disease (CAD))1.034<0.05Gene-array27142736

Compile date 02-09-2018© C/VD project