cvd-logocvd - Molecule ID A2490

geneSULF2, UNQ559/PRO1120, UNQ559
nameExtracellular sulfatase Sulf-2 precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
SULF2_HUMANQ8IWU5ENSG0000019656255959Hs.162016610013

Functions and classifications

GOC:cell surface, C:endoplasmic reticulum, C:extracellular space, C:Golgi stack, C:plasma membrane, F:arylsulfatase activity, F:calcium ion binding, F:N-acetylglucosamine-6-sulfatase activity, P:bone development, P:chondrocyte development, P:embryonic skeletal system development, P:esophagus smooth muscle contraction, P:glial cell-derived neurotrophic factor receptor signaling pathway, P:glomerular basement membrane development, P:glomerular filtration, P:heparan sulfate proteoglycan metabolic process, P:innervation, P:negative regulation of fibroblast growth factor receptor signaling pathway, P:positive regulation of Wnt signaling pathway, P:positive regulation vascular endothelial growth factor production, C:Golgi apparatus, F:sulfuric ester hydrolase activity, F:catalytic activity, P:positive regulation of Wnt receptor signaling pathway, C:cell surface, C:endoplasmic reticulum, C:extracellular space, C:Golgi stack, C:plasma membrane, F:arylsulfatase activity, F:calcium ion binding, F:N-acetylglucosamine-6-sulfatase activity, P:bone development, P:chondrocyte development, P:embryonic skeletal system development, P:esophagus smooth muscle contraction, P:glial cell-derived neurotrophic factor receptor signaling pathway, P:glomerular basement membrane development, P:glomerular filtration, P:heparan sulfate proteoglycan metabolic process, P:innervation, P:negative regulation of fibroblast growth factor receptor signaling pathway, P:positive regulation of Wnt signaling pathway, P:positive regulation vascular endothelial growth factor production, C:Golgi apparatus, F:sulfuric ester hydrolase activity, F:catalytic activity, P:positive regulation of Wnt receptor signaling pathway
UniProtAlternative splicing, Calcium, Complete proteome, Endoplasmic reticulum, Glycoprotein, Golgi apparatus, Hydrolase, Metal-binding, Polymorphism, Reference proteome, Signal
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp25668619Homo sapiens10urinewholeCAD (Stable Coronary Artery Disease)4.298<0.05nanoLC-ESI-MS/MS25668619

Compile date 02-09-2018© C/VD project