cvd-logocvd - Molecule ID A2461

geneASH1L, KMT2H
nameAbsent, small, or homeotic 1-like
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ASH1L_HUMANQ9NR48ENSG0000011653955870Hs.491060607999

Functions and classifications

GOC:nucleus, F:chromatin binding, F:DNA binding, bending, F:ligand-dependent nuclear receptor transcription coactivator activity, F:metal ion binding, F:RNA polymerase II transcription cofactor activity, F:sequence-specific DNA binding transcription factor activity, P:cholesterol catabolic process, P:homeostatic process, P:multicellular organismal development, P:positive regulation of transcription, DNA-templated, P:regulation of hormone biosynthetic process, P:steroid biosynthetic process, C:nucleus, F:DNA binding, F:zinc ion binding, P:positive regulation of transcription, DNA-dependent
UniProt3D-structure, Acetylation, Activator, Alternative splicing, Bromodomain, Cell junction, Chromatin regulator, Chromosome, Complete proteome, Isopeptide bond, Metal-binding, Methyltransferase, Nucleus, Phosphoprotein, Polymorphism, Reference proteome, Repeat, S-adenosyl-L-methionine, Tight junction, Transcription, Transcription regulation, Transferase, Ubl conjugation, Zinc, Zinc-finger
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19059264Homo sapiens31bloodmonocytes and T-helper cellsAtherosclerosis (Coronary Atherosclerosis)0.931<0.05Gene-array19059264
Exp21804111Mus musculus9aorta CAD (Coronary artery disease (CAD))1.271<0.05Gene-array21804111
Exp21868699aMus musculus20macrophages Atherosclerosis (Atherosclerosis)0.642<0.05Gene-array21868699
Exp21868699bMus musculus40aorta and macrophages CAD (Coronary artery disease (CAD))0.642<0.05Gene-array21868699
Exp24082102Mus musculus88heartwholeCAD (Coronary artery disease (CAD))1.218<0.05Gene-array24082102
Exp24530965Homo sapiens23bloodmononuclear cells (PBMCs)CAD (Familial Hypercholesterolemia and Coronary artery disease (CAD))3.434<0.05Gene-array24530965
Exp25835000Homo sapiens31macrophages CAD (Coronary artery disease (CAD))1.440<0.05Gene-array25835000
Exp27142736Mus musculus12liver CAD (Coronary artery disease (CAD))1.059<0.05Gene-array27142736

Compile date 02-09-2018© C/VD project