cvd-logocvd - Molecule ID A245A

geneARNTL, BHLHE5, BMAL1
nameAryl hydrocarbon receptor nuclear translocator-like protein 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BMAL1_HUMANO00327ENSG00000133794406Hs.65734602550

Functions and classifications

GOC:cytoplasm, C:nuclear body, C:transcription factor complex, F:DNA binding, F:Hsp90 protein binding, F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity, F:RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription, F:signal transducer activity, P:circadian regulation of gene expression, P:positive regulation of transcription from RNA polymerase II promoter, P:protein import into nucleus, translocation, P:regulation of protein catabolic process, C:nuclear body, P:regulation of protein catabolic process, P:transcription from RNA polymerase II promoter, C:nucleus, F:sequence-specific DNA binding transcription factor activity, P:transcription, DNA-templated, C:cytoplasm, F:signal transducer activity, P:regulation of transcription, DNA-dependent, C:transcription factor complex, P:circadian rhythm, P:transcription, DNA-dependent, C:cytoplasm, C:nuclear body, C:transcription factor complex, F:DNA binding, F:Hsp90 protein binding, F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity, F:RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription, F:signal transducer activity, P:circadian regulation of gene expression, P:positive regulation of transcription from RNA polymerase II promoter, P:protein import into nucleus, translocation, P:regulation of protein catabolic process, C:nuclear body, P:regulation of protein catabolic process, P:transcription from RNA polymerase II promoter, C:nucleus, F:sequence-specific DNA binding transcription factor activity, P:transcription, DNA-templated, C:cytoplasm, F:signal transducer activity, P:regulation of transcription, DNA-dependent, C:transcription factor complex, P:circadian rhythm, P:transcription, DNA-dependent
UniProt3D-structure, Acetylation, Activator, Alternative splicing, Biological rhythms, Complete proteome, DNA-binding, Isopeptide bond, Nucleus, Phosphoprotein, Reference proteome, Repeat, Transcription, Transcription regulation, Ubl conjugation, Receptor
PADBTF: transcription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseP-valueDetectionPubMed/DOI
Exp24339868Homo sapiens17heartapex left ventricleDCM (Dilated cardiomyopathy (DCM))1.96E-06Gene-array24339868

Compile date 02-09-2018© C/VD project