cvd-logocvd - Molecule ID A2381

geneARHGEF17, TEM4
nameRHO guanine nucleotide exchange factor 17
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGene
ARHGH_HUMANQ96PE2ENSG000001102379828Hs.533719

Functions and classifications

GOC:cytosol, F:guanyl-nucleotide exchange factor activity, F:Rho guanyl-nucleotide exchange factor activity, P:actin cytoskeleton organization, P:apoptotic signaling pathway, P:neurotrophin TRK receptor signaling pathway, P:positive regulation of apoptotic process, P:regulation of Rho GTPase activity, P:small GTPase mediated signal transduction, P:apoptotic process, P:nerve growth factor receptor signaling pathway, P:regulation of Rho protein signal transduction, P:regulation of small GTPase mediated signal transduction, C:intracellular, C:cytosol, F:guanyl-nucleotide exchange factor activity, F:Rho guanyl-nucleotide exchange factor activity, P:actin cytoskeleton organization, P:apoptotic signaling pathway, P:neurotrophin TRK receptor signaling pathway, P:positive regulation of apoptotic process, P:regulation of Rho GTPase activity, P:small GTPase mediated signal transduction, P:apoptotic process, P:nerve growth factor receptor signaling pathway, P:regulation of Rho protein signal transduction, P:regulation of small GTPase mediated signal transduction, C:intracellular
UniProtComplete proteome, Guanine-nucleotide releasing factor, Phosphoprotein, Polymorphism, Reference proteome
PADBMOD: modulator, regulator

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp27234505Homo sapiens35bloodplasmaMI (Myocardial Ischemic Injury)0.643<0.05LC-MS/MS27234505

Compile date 02-09-2018© C/VD project