cvd-logocvd - Molecule ID A2380

geneSRGAP2, ARHGAP34, FNBP2
nameSLIT-ROBO RHO GTPase-activating protein 2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
SRGP2_HUMANO75044ENSG0000016348623380Hs.497575606524

Functions and classifications

GOC:cell junction, C:cytosol, C:dendritic spine head, C:lamellipodium, C:nucleus, C:phagocytic vesicle, C:postsynaptic density, C:postsynaptic membrane, F:protein homodimerization activity, F:Rac GTPase activator activity, F:Rac GTPase binding, P:actin filament severing, P:axon guidance, P:dendritic spine development, P:extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration, P:filopodium assembly, P:lamellipodium assembly involved in ameboidal cell migration, P:negative regulation of neuron migration, P:small GTPase mediated signal transduction, P:substrate adhesion-dependent cell spreading, C:intracellular, P:signal transduction, C:mitochondrial inner membrane, P:neuron projection morphogenesis, C:plasma membrane
UniProt3D-structure, Cell junction, Cell membrane, Cell projection, Chromosomal rearrangement, Coiled coil, Complete proteome, Cytoplasm, Cytoplasmic vesicle, GTPase activation, Membrane, Methylation, Neurogenesis, Nucleus, Phosphoprotein, Polymorphism, Postsynaptic cell membrane, Reference proteome, SH3 domain, Synapse
PADBTF: transcription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseP-valueDetectionPubMed/DOI
Exp26690514Homo sapiens24bloodwholeCAD (Coronary artery disease (CAD))1.89E-04Gene-array26690514

Compile date 02-09-2018© C/VD project