cvd-logocvd - Molecule ID A209A

geneAFF4, AF5Q31, MCEF
nameAF5q31 protein
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AFF4_HUMANQ9UHB7ENSG0000007236427125Hs.519313604417

Functions and classifications

GOC:mitochondrion, C:nucleolus, F:sequence-specific DNA binding transcription factor activity, P:spermatid development, P:transcription from RNA polymerase II promoter, C:nucleus
UniProt3D-structure, Alternative splicing, Chromosomal rearrangement, Complete proteome, Direct protein sequencing, Nucleus, Phosphoprotein, Polymorphism, Proto-oncogene, Reference proteome, Transcription, Transcription regulation
PADBTF: transcription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19059264Homo sapiens31bloodmonocytes and T-helper cellsAtherosclerosis (Coronary Atherosclerosis)0.644<0.05Gene-array19059264
Exp21804111Mus musculus9aorta CAD (Coronary artery disease (CAD))1.966<0.05Gene-array21804111
Exp21868699aMus musculus20macrophages Atherosclerosis (Atherosclerosis)1.150<0.05Gene-array21868699
Exp21868699bMus musculus40aorta and macrophages CAD (Coronary artery disease (CAD))1.150<0.05Gene-array21868699
Exp24082102Mus musculus88heartwholeCAD (Coronary artery disease (CAD))1.331<0.05Gene-array24082102
Exp24530965Homo sapiens23bloodmononuclear cells (PBMCs)CAD (Familial Hypercholesterolemia and Coronary artery disease (CAD))0.763<0.05Gene-array24530965
Exp25835000Homo sapiens31macrophages CAD (Coronary artery disease (CAD))0.717<0.05Gene-array25835000
Exp27142736Mus musculus12liver CAD (Coronary artery disease (CAD))0.890<0.05Gene-array27142736

Compile date 02-09-2018© C/VD project