cvd-logocvd - Molecule ID A1727

geneMAP3K9, MLK1, PRKE1
nameMitogen-activated protein kinase kinase kinase 9
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
M3K9_HUMANP80192ENSG000000064324293Hs.445496600136

Functions and classifications

GOF:ATP binding, F:JUN kinase kinase kinase activity, F:MAP kinase kinase activity, F:protein homodimerization activity, F:protein tyrosine kinase activity, P:activation of JUN kinase activity, P:apoptotic process, P:peptidyl-tyrosine phosphorylation, P:positive regulation of apoptotic process, P:protein autophosphorylation, P:regulation of transcription, DNA-templated, P:transcription, DNA-templated, F:kinase activity, P:cell death, F:ATP binding, F:MAP kinase kinase kinase activity, P:activation of MAPKK activity, P:MAPK cascade, P:regulation of transcription, DNA-dependent, P:transcription, DNA-dependent
UniProt3D-structure, Alternative splicing, Apoptosis, ATP-binding, Complete proteome, Kinase, Nucleotide-binding, Phosphoprotein, Polymorphism, Reference proteome, Repeat, Serine/threonine-protein kinase, SH3 domain, Stress response, Transcription, Transcription regulation, Transferase
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp21235297Homo sapiens14bone_marrowCD133(+) cellsCAD (Coronary artery disease (CAD))-2.530<0.05Gene-array21235297

Compile date 02-09-2018© C/VD project