cvd-logocvd - Molecule ID A1592

geneF13A1, F13A
nameCoagulation factor XIII A chain precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
F13A_HUMANP00488ENSG000001244912162Hs.335513134570, 613225

Functions and classifications

GOC:extracellular region, C:platelet alpha granule lumen, F:metal ion binding, F:protein-glutamine gamma-glutamyltransferase activity, P:peptide cross-linking, P:platelet activation, P:platelet degranulation, P:blood coagulation
UniProt3D-structure, Acetylation, Acyltransferase, Blood coagulation, Calcium, Complete proteome, Cytoplasm, Direct protein sequencing, Disease mutation, Glycoprotein, Hemostasis, Metal-binding, Polymorphism, Reference proteome, Secreted, Transferase, Zymogen
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19059264Homo sapiens31bloodmonocytes and T-helper cellsAtherosclerosis (Coronary Atherosclerosis)0.567<0.05Gene-array19059264
Exp21804111Mus musculus9aorta CAD (Coronary artery disease (CAD))1.341<0.05Gene-array21804111
Exp21868699aMus musculus20macrophages Atherosclerosis (Atherosclerosis)1.138<0.05Gene-array21868699
Exp21868699bMus musculus40aorta and macrophages CAD (Coronary artery disease (CAD))1.138<0.05Gene-array21868699
Exp24082102Mus musculus88heartwholeCAD (Coronary artery disease (CAD))1.306<0.05Gene-array24082102
Exp24530965Homo sapiens23bloodmononuclear cells (PBMCs)CAD (Familial Hypercholesterolemia and Coronary artery disease (CAD))0.285<0.05Gene-array24530965
Exp25835000Homo sapiens31macrophages CAD (Coronary artery disease (CAD))0.656<0.05Gene-array25835000
Exp27142736Mus musculus12liver CAD (Coronary artery disease (CAD))0.505<0.05Gene-array27142736

Compile date 02-09-2018© C/VD project