cvd-logocvd - Molecule ID A1315

geneBHLHB2, BHLHE40, Dec-01
nameClass E basic helix-loop-helix protein 40
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BHE40_HUMANO14503ENSG000001341078553Hs.744856604256

Functions and classifications

GOC:Golgi apparatus, C:nucleolus, F:E-box binding, F:MRF binding, F:protein homodimerization activity, F:RNA polymerase II activating transcription factor binding, F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, F:RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription, P:circadian regulation of gene expression, P:entrainment of circadian clock by photoperiod, P:negative regulation of sequence-specific DNA binding transcription factor activity, P:negative regulation of transcription from RNA polymerase II promoter, P:transcription from RNA polymerase II promoter, P:regulation of neuronal synaptic plasticity, C:Golgi apparatus, F:DNA binding, P:circadian rhythm, P:negative regulation of transcription, DNA-dependent, P:regulation of neuronal synaptic plasticity, C:Golgi apparatus, C:nucleolus, F:E-box binding, F:MRF binding, F:protein homodimerization activity, F:RNA polymerase II activating transcription factor binding, F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, F:RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription, P:circadian regulation of gene expression, P:entrainment of circadian clock by photoperiod, P:negative regulation of sequence-specific DNA binding transcription factor activity, P:negative regulation of transcription from RNA polymerase II promoter, P:transcription from RNA polymerase II promoter, P:regulation of neuronal synaptic plasticity, C:Golgi apparatus, F:DNA binding, P:circadian rhythm, P:negative regulation of transcription, DNA-dependent, P:regulation of neuronal synaptic plasticity
UniProtComplete proteome, DNA-binding, Nucleus, Reference proteome, Transcription, Transcription regulation, Ubl conjugation, Phosphoprotein
PADBTF: transcription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseP-valueDetectionPubMed/DOI
Exp19336532bHomo sapiens24bloodmononuclear cellsNICM (Non-ischemic dilated cardiomyopathy (NIDCM) )0.0036204Gene-array19336532
Exp19336532cHomo sapiens24bloodmononuclear cellsICM (Ischemic cardiomyopathy (ICM))0.00796853Gene-array19336532

Compile date 02-09-2018© C/VD project