cvd-logocvd - Molecule ID A0812

geneADRB2, ADRB2R, B2AR
nameBeta-2 adrenergic receptor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ADRB2_HUMANP07550ENSG00000169252154Hs.2551109690

Functions and classifications

GOC:cytoplasmic side of plasma membrane, C:midbody, C:mitotic spindle, C:nucleus, C:spindle midzone, F:GDP binding, F:GTP binding, F:GTPase activity, F:magnesium ion binding, P:cell surface receptor signaling pathway, P:chromosome organization, P:immune response, P:mitosis, P:small GTPase mediated signal transduction, C:membrane, P:signal transduction, C:internal side of plasma membrane
UniProt3D-structure, Cell membrane, Complete proteome, Disulfide bond, G-protein coupled receptor, Glycoprotein, Hydroxylation, Lipoprotein, Membrane, Palmitate, Phosphoprotein, Polymorphism, Receptor, Reference proteome, Transducer, Transmembrane, Transmembrane helix, Ubl conjugation
PADBRCP: receptor

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19059264Homo sapiens31bloodmonocytes and T-helper cellsAtherosclerosis (Coronary Atherosclerosis)0.643<0.05Gene-array19059264
Exp21804111Mus musculus9aorta CAD (Coronary artery disease (CAD))0.962<0.05Gene-array21804111
Exp21868699aMus musculus20macrophages Atherosclerosis (Atherosclerosis)0.702<0.05Gene-array21868699
Exp21868699bMus musculus40aorta and macrophages CAD (Coronary artery disease (CAD))0.702<0.05Gene-array21868699
Exp24082102Mus musculus88heartwholeCAD (Coronary artery disease (CAD))1.219<0.05Gene-array24082102
Exp24530965Homo sapiens23bloodmononuclear cells (PBMCs)CAD (Familial Hypercholesterolemia and Coronary artery disease (CAD))0.287<0.05Gene-array24530965
Exp25835000Homo sapiens31macrophages CAD (Coronary artery disease (CAD))1.775<0.05Gene-array25835000
Exp27142736Mus musculus12liver CAD (Coronary artery disease (CAD))1.241<0.05Gene-array27142736

Compile date 02-09-2018© C/VD project