cvd-logocvd - Molecule ID A0704

geneARHGDIA, GDIA1
nameRho GDP-dissociation inhibitor 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
GDIR1_HUMANP52565ENSG00000141522396Hs.159161601925, 615244

Functions and classifications

GOC:cytoskeleton, C:cytosol, C:immunological synapse, F:GTPase activator activity, F:Rho GDP-dissociation inhibitor activity, P:cellular component movement, P:negative regulation of apoptotic process, P:negative regulation of axonogenesis, P:negative regulation of cell adhesion, P:neurotrophin TRK receptor signaling pathway, P:positive regulation of axonogenesis, P:positive regulation of GTPase activity, P:regulation of protein localization, P:regulation of small GTPase mediated signal transduction, P:Rho protein signal transduction, C:cytoplasm, P:regulation of catalytic activity, P:nerve growth factor receptor signaling pathway, C:cytoskeleton, C:cytosol, C:immunological synapse, F:GTPase activator activity, F:Rho GDP-dissociation inhibitor activity, P:cellular component movement, P:negative regulation of apoptotic process, P:negative regulation of axonogenesis, P:negative regulation of cell adhesion, P:neurotrophin TRK receptor signaling pathway, P:positive regulation of axonogenesis, P:positive regulation of GTPase activity, P:regulation of protein localization, P:regulation of small GTPase mediated signal transduction, P:Rho protein signal transduction, C:cytoplasm, P:regulation of catalytic activity, P:nerve growth factor receptor signaling pathway
UniProt3D-structure, Acetylation, Alternative splicing, Complete proteome, Cytoplasm, Direct protein sequencing, Disease mutation, GTPase activation, Phosphoprotein, Reference proteome
PADBDIS: disease

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseP-valueDetectionPubMed/DOI
Exp22427379cHomo sapiens17heartleft ventricle biopsiesNDHF (Non-diabetic heart failure (NDHF))0.003313Gene-array22427379
Exp24801707Homo sapiens52blood AMI (Myocardial infarction)0.04978Whole-genome gene expression24801707

Compile date 02-09-2018© C/VD project