cvd-logocvd - Molecule ID A0691

geneAP1S1, AP19, CLAPS1
nameAdapter-related protein complex 1 sigma 1A subunit
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AP1S1_HUMANP61966ENSG000001063671174Hs.489365603531, 609313

Functions and classifications

GOC:nucleolus, C:nucleoplasm, C:ribonucleoprotein complex, C:transcription factor TFIIIC complex, F:DNA binding, P:5S class rRNA transcription from RNA polymerase III type 1 promoter, P:tRNA transcription from RNA polymerase III promoter
UniProtAlternative splicing, Coated pit, Complete proteome, Cytoplasmic vesicle, Deafness, Golgi apparatus, Ichthyosis, Membrane, Mental retardation, Neuropathy, Phosphoprotein, Protein transport, Reference proteome, Transport, Endocytosis
PADBTP: transport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19059264Homo sapiens31bloodmonocytes and T-helper cellsAtherosclerosis (Coronary Atherosclerosis)0.652<0.05Gene-array19059264
Exp21804111Mus musculus9aorta CAD (Coronary artery disease (CAD))0.932<0.05Gene-array21804111
Exp21868699aMus musculus20macrophages Atherosclerosis (Atherosclerosis)1.663<0.05Gene-array21868699
Exp21868699bMus musculus40aorta and macrophages CAD (Coronary artery disease (CAD))1.663<0.05Gene-array21868699
Exp24082102Mus musculus88heartwholeCAD (Coronary artery disease (CAD))1.620<0.05Gene-array24082102
Exp24530965Homo sapiens23bloodmononuclear cells (PBMCs)CAD (Familial Hypercholesterolemia and Coronary artery disease (CAD))1.764<0.05Gene-array24530965
Exp25835000Homo sapiens31macrophages CAD (Coronary artery disease (CAD))2.148<0.05Gene-array25835000
Exp27142736Mus musculus12liver CAD (Coronary artery disease (CAD))1.192<0.05Gene-array27142736

Compile date 02-09-2018© C/VD project