cvd-logocvd - Molecule ID A0647

geneANXA1, ANX1, LPC1
nameAnnexin A1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ANXA1_HUMANP04083ENSG00000135046301Hs.494173151690

Functions and classifications

GOC:basolateral plasma membrane, C:cilium, C:cornified envelope, C:cytoplasm, C:extracellular space, C:extracellular vesicular exosome, C:mitochondrial membrane, C:nucleus, C:plasma membrane, C:protein complex, C:sarcolemma, F:calcium ion binding, F:calcium-dependent phospholipid binding, F:phospholipase A2 inhibitor activity, F:protein binding, bridging, F:receptor binding, F:structural molecule activity, P:alpha-beta T cell differentiation, P:arachidonic acid secretion, P:cell surface receptor signaling pathway, P:cellular component movement, P:cellular response to glucocorticoid stimulus, P:cellular response to hydrogen peroxide, P:endocrine pancreas development, P:estrous cycle phase, P:gliogenesis, P:hepatocyte differentiation, P:inflammatory response, P:insulin secretion, P:keratinocyte differentiation, P:negative regulation of acute inflammatory response, P:negative regulation of apoptotic process, P:negative regulation of protein secretion, P:neutrophil clearance, P:peptide cross-linking, P:positive regulation of G1/S transition of mitotic cell cycle, P:positive regulation of neutrophil apoptotic process, P:positive regulation of prostaglandin biosynthetic process, P:positive regulation of vesicle fusion, P:regulation of cell proliferation, P:response to drug, P:response to estradiol, P:response to interleukin-1, P:response to peptide hormone, P:response to X-ray, P:negative regulation of catalytic activity, P:neutrophil homeostasis, P:response to X-ray, F:phospholipase inhibitor activity, F:single-stranded DNA binding, F:single-stranded RNA binding, P:cell cycle, P:positive regulation of apoptotic process, P:response to estradiol stimulus, P:response to peptide hormone stimulus, P:response to glucocorticoid stimulus, C:basolateral plasma membrane, C:cilium, C:cornified envelope, C:cytoplasm, C:extracellular space, C:extracellular vesicular exosome, C:mitochondrial membrane, C:nucleus, C:plasma membrane, C:protein complex, C:sarcolemma, F:calcium ion binding, F:calcium-dependent phospholipid binding, F:phospholipase A2 inhibitor activity, F:protein binding, bridging, F:receptor binding, F:structural molecule activity, P:alpha-beta T cell differentiation, P:arachidonic acid secretion, P:cell surface receptor signaling pathway, P:cellular component movement, P:cellular response to glucocorticoid stimulus, P:cellular response to hydrogen peroxide, P:endocrine pancreas development, P:estrous cycle phase, P:gliogenesis, P:hepatocyte differentiation, P:inflammatory response, P:insulin secretion, P:keratinocyte differentiation, P:negative regulation of acute inflammatory response, P:negative regulation of apoptotic process, P:negative regulation of protein secretion, P:neutrophil clearance, P:peptide cross-linking, P:positive regulation of G1/S transition of mitotic cell cycle, P:positive regulation of neutrophil apoptotic process, P:positive regulation of prostaglandin biosynthetic process, P:positive regulation of vesicle fusion, P:regulation of cell proliferation, P:response to drug, P:response to estradiol, P:response to interleukin-1, P:response to peptide hormone, P:response to X-ray, P:negative regulation of catalytic activity, P:neutrophil homeostasis, P:response to X-ray, F:phospholipase inhibitor activity, F:single-stranded DNA binding, F:single-stranded RNA binding, P:cell cycle, P:positive regulation of apoptotic process, P:response to estradiol stimulus, P:response to peptide hormone stimulus, P:response to glucocorticoid stimulus
UniProt3D-structure, Acetylation, Annexin, Calcium, Calcium/phospholipid-binding, Cell membrane, Cell projection, Cilium, Complete proteome, Cytoplasm, Direct protein sequencing, Isopeptide bond, Membrane, Nucleus, Phospholipase A2 inhibitor, Phosphoprotein, Reference proteome, Repeat
PADBINH: inhibitor (protease, kinase, other enzymes, pathways)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp21173733Homo sapiens10bloodwholeAtherosclerosis (Atherosclerosis familial hypercholesterolemia) 0.0150228Gene-array21173733
Exp21417265Homo sapiens17heartmyocardiumDCM (Dilated cardiomyopathy)1.6000.03LC-MS/MS21417265

Compile date 02-09-2018© C/VD project