cvd-logocvd - Molecule ID A0488

geneARNT, BHLHE2
nameAryl hydrocarbon receptor nuclear translocator
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ARNT_HUMANP27540ENSG00000143437405Hs.632446126110

Functions and classifications

GOC:cytoplasm, C:nucleoplasm, C:transcription factor complex, F:aryl hydrocarbon receptor activity, F:DNA binding, F:sequence-specific DNA binding transcription factor activity, F:transcription coactivator activity, P:cell differentiation, P:embryonic placenta development, P:mRNA transcription from RNA polymerase II promoter, P:positive regulation of endothelial cell proliferation, P:positive regulation of erythrocyte differentiation, P:positive regulation of glycolysis, P:positive regulation of hormone biosynthetic process, P:positive regulation of protein sumoylation, P:positive regulation of transcription from RNA polymerase II promoter, P:positive regulation of transcription, DNA-templated, P:positive regulation of vascular endothelial growth factor receptor signaling pathway, P:positive regulation vascular endothelial growth factor production, P:regulation of transcription from RNA polymerase II promoter in response to hypoxia, P:regulation of transcription from RNA polymerase II promoter in response to oxidative stress, C:nucleus, F:signal transducer activity, P:transcription, DNA-templated, F:sequence-specific DNA binding, P:positive regulation of transcription, DNA-dependent, P:transcription, DNA-dependent, P:regulation of transcription, DNA-dependent, P:signal transduction, C:cytoplasm, C:nucleoplasm, C:transcription factor complex, F:aryl hydrocarbon receptor activity, F:DNA binding, F:sequence-specific DNA binding transcription factor activity, F:transcription coactivator activity, P:cell differentiation, P:embryonic placenta development, P:mRNA transcription from RNA polymerase II promoter, P:positive regulation of endothelial cell proliferation, P:positive regulation of erythrocyte differentiation, P:positive regulation of glycolysis, P:positive regulation of hormone biosynthetic process, P:positive regulation of protein sumoylation, P:positive regulation of transcription from RNA polymerase II promoter, P:positive regulation of transcription, DNA-templated, P:positive regulation of vascular endothelial growth factor receptor signaling pathway, P:positive regulation vascular endothelial growth factor production, P:regulation of transcription from RNA polymerase II promoter in response to hypoxia, P:regulation of transcription from RNA polymerase II promoter in response to oxidative stress, C:nucleus, F:signal transducer activity, P:transcription, DNA-templated, F:sequence-specific DNA binding, P:positive regulation of transcription, DNA-dependent, P:transcription, DNA-dependent, P:regulation of transcription, DNA-dependent, P:signal transduction
UniProt3D-structure, Acetylation, Activator, Alternative splicing, Complete proteome, Direct protein sequencing, DNA-binding, Nucleus, Phosphoprotein, Polymorphism, Reference proteome, Repeat, Transcription, Transcription regulation, Receptor
PADBTF: transcription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseP-valueDetectionPubMed/DOI
Exp17106732Homo sapiens12heartendocardiumDCMi (Inflammatory dilated cardiomyopathy (DCMi))3.71E-04Gene-array17106732
Exp24801707Homo sapiens52blood AMI (Myocardial infarction)0.02253Whole-genome gene expression24801707

Compile date 02-09-2018© C/VD project