cvd-logocvd - Molecule ID A043C

geneKPNB1, NTF97
nameImportin beta-1 subunit
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
IMB1_HUMANQ14974ENSG000001084243837Hs.532793602738

Functions and classifications

GOC:cytosol, C:nuclear membrane, C:nuclear pore, C:nucleoplasm, F:nuclear localization sequence binding, F:protein transporter activity, F:zinc ion binding, P:apoptotic DNA fragmentation, P:cytokine-mediated signaling pathway, P:intracellular transport of virus, P:NLS-bearing protein import into nucleus, P:protein import into nucleus, translocation, P:ribosomal protein import into nucleus, P:small molecule metabolic process, C:cytoplasm, C:protein complex, P:intracellular protein transport, P:nucleocytoplasmic transport, P:protein transport, P:NLS-bearing substrate import into nucleus, P:viral infectious cycle, P:virus-host interaction
UniProt3D-structure, Acetylation, ADP-ribosylation, Complete proteome, Cytoplasm, Direct protein sequencing, Host-virus interaction, Isopeptide bond, Nucleus, Phosphoprotein, Protein transport, Reference proteome, Repeat, Transport, Ubl conjugation
PADBTP: transport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19059264Homo sapiens31bloodmonocytes and T-helper cellsAtherosclerosis (Coronary Atherosclerosis)1.213<0.05Gene-array19059264
Exp21804111Mus musculus9aorta CAD (Coronary artery disease (CAD))1.041<0.05Gene-array21804111
Exp21868699aMus musculus20macrophages Atherosclerosis (Atherosclerosis)0.758<0.05Gene-array21868699
Exp21868699bMus musculus40aorta and macrophages CAD (Coronary artery disease (CAD))0.758<0.05Gene-array21868699
Exp24082102Mus musculus88heartwholeCAD (Coronary artery disease (CAD))1.678<0.05Gene-array24082102
Exp24530965Homo sapiens23bloodmononuclear cells (PBMCs)CAD (Familial Hypercholesterolemia and Coronary artery disease (CAD))0.673<0.05Gene-array24530965
Exp25835000Homo sapiens31macrophages CAD (Coronary artery disease (CAD))1.901<0.05Gene-array25835000
Exp27142736Mus musculus12liver CAD (Coronary artery disease (CAD))1.342<0.05Gene-array27142736

Compile date 02-09-2018© C/VD project