cvd-logocvd - Molecule ID A0429

geneACO2
nameAconitate hydratase, mitochondrial precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACON_HUMANQ99798ENSG0000010041250Hs.643610100850, 614559

Functions and classifications

GOC:mitochondrial matrix, C:nucleus, F:3 iron, 4 sulfur cluster binding, F:4 iron, 4 sulfur cluster binding, F:aconitate hydratase activity, F:iron ion binding, P:cell death, P:citrate metabolic process, P:isocitrate metabolic process, P:tricarboxylic acid cycle, F:4 iron, 4 sulfur cluster binding, C:mitochondrion, F:citrate hydro-lyase (cis-aconitate-forming) activity, F:isocitrate hydro-lyase (cis-aconitate-forming) activity, C:mitochondrial matrix, C:nucleus, F:3 iron, 4 sulfur cluster binding, F:4 iron, 4 sulfur cluster binding, F:aconitate hydratase activity, F:iron ion binding, P:cell death, P:citrate metabolic process, P:isocitrate metabolic process, P:tricarboxylic acid cycle, F:4 iron, 4 sulfur cluster binding, C:mitochondrion, F:citrate hydro-lyase (cis-aconitate-forming) activity, F:isocitrate hydro-lyase (cis-aconitate-forming) activity
UniProt4Fe-4S, Acetylation, Complete proteome, Direct protein sequencing, Disease mutation, Iron, Iron-sulfur, Isopeptide bond, Lyase, Metal-binding, Mitochondrion, Neurodegeneration, Phosphoprotein, Polymorphism, Pyrrolidone carboxylic acid, Reference proteome, Transit peptide, Tricarboxylic acid cycle, Ubl conjugation
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp21417265Homo sapiens17heartmyocardiumDCM (Dilated cardiomyopathy)1.3000.004LC-MS/MS21417265

Compile date 02-09-2018© C/VD project