cvd-logocvd - Molecule ID A0377

geneATP5A1, ATP5A, ATP5AL2
nameATP synthase alpha chain, mitochondrial precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ATPA_HUMANP25705ENSG00000152234498Hs.298280164360, 615228

Functions and classifications

GOC:basal plasma membrane, C:caveola, C:external side of plasma membrane, C:integral component of membrane, C:plasma membrane, F:ADP receptor activity, F:G-protein coupled adenosine receptor activity, F:guanyl-nucleotide exchange factor activity, P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway, P:calcium ion transmembrane transport, P:cell projection organization, P:G-protein coupled purinergic nucleotide receptor signaling pathway, P:negative regulation of cell differentiation, P:negative regulation of norepinephrine secretion, P:platelet activation, P:platelet aggregation, P:positive regulation of ion transport, P:potassium ion transmembrane transport, P:protein kinase B signaling, P:regulation of calcium ion transport, F:G-protein coupled purinergic nucleotide receptor activity, P:blood coagulation, C:integral to membrane, C:mitochondrion, P:protein kinase B signaling cascade
UniProtAcetylation, Alternative splicing, ATP synthesis, ATP-binding, Cell membrane, CF(1), Complete proteome, Direct protein sequencing, Disease mutation, Hydrogen ion transport, Ion transport, Membrane, Mitochondrion, Mitochondrion inner membrane, Nucleotide-binding, Phosphoprotein, Polymorphism, Pyrrolidone carboxylic acid, Reference proteome, Transit peptide, Transport
PADBTP: transport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp21235297Homo sapiens14bone_marrowCD133(+) cellsCAD (Coronary artery disease (CAD))2.100<0.05Gene-array21235297

Compile date 02-09-2018© C/VD project