cvd-logocvd - Molecule ID A0373

geneADAM22, MDC2
nameADAM 22 precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ADA22_HUMANQ9P0K1ENSG0000000827753616Hs.256398603709

Functions and classifications

GOC:actin cytoskeleton, C:cell surface, C:cell-cell junction, C:centrosome, C:cytosol, C:extracellular vesicular exosome, C:focal adhesion, C:intracellular membrane-bounded organelle, C:plasma membrane, C:ruffle, C:ruffle membrane, F:structural constituent of cytoskeleton, P:activation of signaling protein activity involved in unfolded protein response, P:axon guidance, P:cell adhesion, P:cell-cell junction assembly, P:cell-substrate junction assembly, P:cellular protein metabolic process, P:cortical actin cytoskeleton organization, P:cytoskeletal anchoring at plasma membrane, P:muscle contraction, P:platelet activation, P:platelet degranulation, F:structural molecule activity, P:cellular component movement
UniProt3D-structure, Alternative splicing, Cell adhesion, Cleavage on pair of basic residues, Complete proteome, Disulfide bond, EGF-like domain, Glycoprotein, Membrane, Phosphoprotein, Polymorphism, Receptor, Reference proteome, Signal, Transmembrane, Transmembrane helix, Integrin, Secreted, Hydrolase, Metal-binding, Metalloprotease, Protease
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp21235297Homo sapiens14bone_marrowCD133(+) cellsCAD (Coronary artery disease (CAD))-2.370<0.05Gene-array21235297

Compile date 02-09-2018© C/VD project