cvd-logocvd - Molecule ID A0252

geneAP2A2, ADTAB, CLAPA2
nameAdapter-related protein complex 2 alpha 2 subunit
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AP2A2_HUMANO94973ENSG00000183020161Hs.19121607242

Functions and classifications

GOC:cytosolic small ribosomal subunit, C:endocytic vesicle lumen, C:extracellular region, C:haptoglobin-hemoglobin complex, C:hemoglobin complex, F:heme binding, F:iron ion binding, F:oxygen binding, F:oxygen transporter activity, P:bicarbonate transport, P:hydrogen peroxide catabolic process, P:oxidation-reduction process, P:oxygen transport, P:positive regulation of cell death, P:protein heterooligomerization, P:small molecule metabolic process
UniProtAlternative splicing, Cell membrane, Coated pit, Complete proteome, Endocytosis, Lipid-binding, Membrane, Protein transport, Reference proteome, Transport, Phosphoprotein
PADBTP: transport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19059264Homo sapiens31bloodmonocytes and T-helper cellsAtherosclerosis (Coronary Atherosclerosis)0.477<0.05Gene-array19059264
Exp21804111Mus musculus9aorta CAD (Coronary artery disease (CAD))1.081<0.05Gene-array21804111
Exp21868699aMus musculus20macrophages Atherosclerosis (Atherosclerosis)1.225<0.05Gene-array21868699
Exp21868699bMus musculus40aorta and macrophages CAD (Coronary artery disease (CAD))1.225<0.05Gene-array21868699
Exp24082102Mus musculus88heartwholeCAD (Coronary artery disease (CAD))1.572<0.05Gene-array24082102
Exp24530965Homo sapiens23bloodmononuclear cells (PBMCs)CAD (Familial Hypercholesterolemia and Coronary artery disease (CAD))2.809<0.05Gene-array24530965
Exp25835000Homo sapiens31macrophages CAD (Coronary artery disease (CAD))0.551<0.05Gene-array25835000
Exp27142736Mus musculus12liver CAD (Coronary artery disease (CAD))1.348<0.05Gene-array27142736

Compile date 02-09-2018© C/VD project