cvd-logocvd - Molecule ID A023I

geneRNF144B, IBRDC2, P53RFP
nameE3 ubiquitin-protein ligase RNF144B
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGene
R144B_HUMANQ7Z419ENSG00000137393255488Hs.148741

Functions and classifications

GOC:integral component of membrane, C:mitochondrial membrane, C:ubiquitin ligase complex, F:ubiquitin-protein ligase activity, F:zinc ion binding, P:apoptotic process, P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process, F:ligase activity, P:metabolic process, C:integral to membrane, F:metal ion binding
UniProtApoptosis, Complete proteome, Cytoplasm, Ligase, Membrane, Metal-binding, Mitochondrion, Reference proteome, Repeat, Transmembrane, Transmembrane helix, Ubl conjugation, Ubl conjugation pathway, Zinc, Zinc-finger
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19059264Homo sapiens31bloodmonocytes and T-helper cellsAtherosclerosis (Coronary Atherosclerosis)0.509<0.05Gene-array19059264
Exp21804111Mus musculus9aorta CAD (Coronary artery disease (CAD))1.153<0.05Gene-array21804111
Exp21868699aMus musculus20macrophages Atherosclerosis (Atherosclerosis)2.189<0.05Gene-array21868699
Exp21868699bMus musculus40aorta and macrophages CAD (Coronary artery disease (CAD))2.189<0.05Gene-array21868699
Exp24082102Mus musculus88heartwholeCAD (Coronary artery disease (CAD))1.608<0.05Gene-array24082102
Exp24530965Homo sapiens23bloodmononuclear cells (PBMCs)CAD (Familial Hypercholesterolemia and Coronary artery disease (CAD))1.345<0.05Gene-array24530965
Exp25835000Homo sapiens31macrophages CAD (Coronary artery disease (CAD))1.415<0.05Gene-array25835000
Exp27142736Mus musculus12liver CAD (Coronary artery disease (CAD))1.328<0.05Gene-array27142736

Compile date 02-09-2018© C/VD project