cvd-logocvd - Molecule ID A0235

geneACTR2, ARP2
nameActin-like protein 2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ARP2_HUMANP61160ENSG0000013807110097Hs.643727604221

Functions and classifications

GOC:actin cap, C:Arp2/3 protein complex, C:cell projection, C:cytosol, F:ATP binding, P:Arp2/3 complex-mediated actin nucleation, P:asymmetric cell division, P:cellular component movement, P:cytoplasmic transport, P:establishment or maintenance of cell polarity, P:Fc-gamma receptor signaling pathway involved in phagocytosis, P:innate immune response, P:meiotic cytokinesis, P:spindle localization, C:cytoplasm, P:actin cytoskeleton organization, P:cytokinesis after meiosis, P:meiotic cell cycle, C:actin cap, C:Arp2/3 protein complex, C:cell projection, C:cytosol, F:ATP binding, P:Arp2/3 complex-mediated actin nucleation, P:asymmetric cell division, P:cellular component movement, P:cytoplasmic transport, P:establishment or maintenance of cell polarity, P:Fc-gamma receptor signaling pathway involved in phagocytosis, P:innate immune response, P:meiotic cytokinesis, P:spindle localization, C:cytoplasm, P:actin cytoskeleton organization, P:cytokinesis after meiosis, P:meiotic cell cycle
UniProtAcetylation, Actin-binding, Alternative splicing, ATP-binding, Cell projection, Complete proteome, Cytoplasm, Cytoskeleton, Direct protein sequencing, Nucleotide-binding, Reference proteome
PADBCS: Cell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19059264Homo sapiens31bloodmonocytes and T-helper cellsAtherosclerosis (Coronary Atherosclerosis)0.692<0.05Gene-array19059264
Exp19336532aHomo sapiens24bloodmononuclear cellsNICM (Non-ischemic dilated cardiomyopathy (NIDCM) ) 0.0037504Gene-array19336532
Exp19336532aHomo sapiens24bloodmononuclear cellsNICM (Non-ischemic dilated cardiomyopathy (NIDCM) ) 0.0255831Gene-array19336532
Exp19336532bHomo sapiens24bloodmononuclear cellsNICM (Non-ischemic dilated cardiomyopathy (NIDCM) ) 0.0105997Gene-array19336532
Exp19336532bHomo sapiens24bloodmononuclear cellsNICM (Non-ischemic dilated cardiomyopathy (NIDCM) ) 0.0111315Gene-array19336532
Exp21173733Homo sapiens10bloodwholeAtherosclerosis (Atherosclerosis familial hypercholesterolemia) 0.0231608Gene-array21173733
Exp21804111Mus musculus9aorta CAD (Coronary artery disease (CAD))0.940<0.05Gene-array21804111
Exp21868699aMus musculus20macrophages Atherosclerosis (Atherosclerosis)0.559<0.05Gene-array21868699
Exp21868699bMus musculus40aorta and macrophages CAD (Coronary artery disease (CAD))0.559<0.05Gene-array21868699
Exp24082102Mus musculus88heartwholeCAD (Coronary artery disease (CAD))1.307<0.05Gene-array24082102
Exp24530965Homo sapiens23bloodmononuclear cells (PBMCs)CAD (Familial Hypercholesterolemia and Coronary artery disease (CAD))0.640<0.05Gene-array24530965
Exp25835000Homo sapiens31macrophages CAD (Coronary artery disease (CAD))0.633<0.05Gene-array25835000
Exp27142736Mus musculus12liver CAD (Coronary artery disease (CAD))1.614<0.05Gene-array27142736

Compile date 02-09-2018© C/VD project