cvd-logocvd - Molecule ID A0050

geneGNAI3
nameGuanine nucleotide-binding protein G(k), alpha subunit
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
GNAI3_HUMANP08754ENSG000000651352773Hs.73799139370, 602483

Functions and classifications

GOC:centrosome, C:Golgi apparatus, C:heterotrimeric G-protein complex, C:lysosomal membrane, C:membrane raft, C:midbody, C:zymogen granule, F:G-protein beta/gamma-subunit complex binding, F:G-protein coupled serotonin receptor binding, F:GTP binding, F:GTPase activity, F:metal ion binding, F:signal transducer activity, P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, P:cell cycle, P:cell division, P:negative regulation of adenylate cyclase activity, P:platelet activation, P:synaptic transmission, P:transport, P:vesicle fusion, C:plasma membrane, P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway, C:cytoplasm, P:negative regulation of synaptic transmission, P:G-protein coupled receptor signaling pathway, C:centrosome, C:Golgi apparatus, C:heterotrimeric G-protein complex, C:lysosomal membrane, C:membrane raft, C:midbody, C:zymogen granule, F:G-protein beta/gamma-subunit complex binding, F:G-protein coupled serotonin receptor binding, F:GTP binding, F:GTPase activity, F:metal ion binding, F:signal transducer activity, P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, P:cell cycle, P:cell division, P:negative regulation of adenylate cyclase activity, P:platelet activation, P:synaptic transmission, P:transport, P:vesicle fusion, C:plasma membrane, P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway, C:cytoplasm, P:negative regulation of synaptic transmission, P:G-protein coupled receptor signaling pathway
UniProt3D-structure, ADP-ribosylation, Cell cycle, Cell division, Cell membrane, Complete proteome, Cytoplasm, Cytoskeleton, Disease mutation, GTP-binding, Lipoprotein, Magnesium, Membrane, Metal-binding, Myristate, Nucleotide-binding, Palmitate, Reference proteome, Transducer
PADBMOD: modulator, regulator

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp25141849aCanis lupus familiaris11bloodserumDHF (Dyssynchronous heart failure (DHF))2.090<0.05LC-MS/MS25141849
Exp25141849bCanis lupus familiaris12bloodserumCRT (Cardiac resynchronization therapy (CRT))1.140<0.05LC-MS/MS25141849

Compile date 02-09-2018© C/VD project