CKDdb-logoCKDdb - Study ID Exp20093355

PubMed ID20093355
AuthorsNakorchevsky A, Hewel JA, Kurian SM, Mondala TS, Campbell D, Head SR, Marsh CL, Yates JR 3rd, Salomon DR.
TitleMolecular mechanisms of chronic kidney transplant rejection via large-scale proteogenomic analysis of tissue biopsies.
JournalJ Am Soc Nephrol. 2010 Feb;21(2):362-73.
AbstractThe most common cause of kidney transplant failure is the poorly characterized histopathologic entity interstitial fibrosis and tubular atrophy (IFTA). There are no known unifying mechanisms, no effective therapy, and no proven preventive strategies. Possible mechanisms include chronic immune rejection, inflammation, drug toxicity, and chronic kidney injury from secondary factors. To gain further mechanistic insight, we conducted a large-scale proteogenomic study of kidney transplant biopsies with IFTA of varying severity. We acquired proteomic data using tandem mass spectrometry with subsequent quantification, analysis of differential protein expression, validation, and functional annotations to known molecular networks. We performed genome-wide expression profiling in parallel. More than 1400 proteins with unique expression profiles traced the progression from normal transplant biopsies to biopsies with mild to moderate and severe disease. Multiple sets of proteins were mapped to different functional pathways, many increasing with histologic severity, including immune responses, inflammatory cell activation, and apoptosis consistent with the chronic rejection hypothesis. Two examples include the extensive population of the alternative rather than the classical complement pathway, previously not appreciated for IFTA, and a comprehensive control network for the actin cytoskeleton and cell signaling of the acute-phase response. In summary, this proteomic effort using kidney tissue contributes mechanistic insight into several biologic processes associated with IFTA.

Sample characteristics

SpeciesTissue / SourceDiseaseNDetection methodSample
Homo sapienskidneyFibrosis33MS/MS, LTQ LX linear ion trapDem20093355

Sample description and preparation

Disease (case)Interstitial fibrosis and tubular atrophy
Digestin-solution, trypsin
Separation2D-HPLC

Molecule list

Molecule IDextExternal IDGeneNameRegulation (case/control)Scores
A0008 CALM_HUMANCALM1, CALM2, CALM3Calmodulinregulation in disease: downquantification method: spectral counting
A0029XANXA6_HUMANANXA6, ANX6Annexin A6regulation in disease: upquantification method: spectral counting
A002C GLRX1_HUMANGLRX, GRXGlutaredoxin-1regulation in disease: downquantification method: spectral counting
A0083 SRC8_HUMANCTTN, EMS1Cortactinregulation in disease: downquantification method: spectral counting
A0089XCTNA1_HUMANCTNNA1Alpha-1 cateninregulation in disease: downquantification method: spectral counting
A0098XVINC_HUMANVCLVinculinregulation in disease: upquantification method: spectral counting
A0119XCLH1_HUMANCLTC, CLH17, CLTCL2Clathrin heavy chain 1regulation in disease: downquantification method: spectral counting
A0155 CDC42_HUMANCDC42Cell division control protein 42 homologregulation in disease: downquantification method: spectral counting
A0191 HS90A_HUMANHSP90AA1, HSP90A, HSPC1Heat shock protein HSP 90-alpharegulation in disease: upquantification method: spectral counting
A021CXHEMO_HUMANHPXHemopexin precursorregulation in disease: upquantification method: spectral counting
A0234 ARP3_HUMANACTR3, ARP3Actin-like protein 3regulation in disease: upquantification method: spectral counting
A0261 K6PF_HUMANPFKM, PFKX6-phosphofructokinaseregulation in disease: upquantification method: spectral counting
A0280 1433E_HUMANYWHAE14-3-3 protein epsilonregulation in disease: upquantification method: spectral counting
A0325 TENS1_HUMANTNS1, TNSTensin-1regulation in disease: upquantification method: spectral counting
A0331 G3P_HUMANGAPD, GAPDHGlyceraldehyde 3-phosphate dehydrogenaseregulation in disease: upquantification method: spectral counting
A0361 1433Z_HUMANYWHAZ14-3-3 protein zeta/deltaregulation in disease: upquantification method: spectral counting
A0362 1433G_HUMANYWHAG14-3-3 protein gammaregulation in disease: upquantification method: spectral counting
A0370 LDHA_HUMANLDHA, PIG19L-lactate dehydrogenase A chainregulation in disease: upquantification method: spectral counting
A0371 PRDX1_HUMANPRDX1, PAGA, PAGBPeroxiredoxin 1regulation in disease: downquantification method: spectral counting
A0377 ATPA_HUMANATP5A1, ATP5A, ATP5AL2ATP synthase alpha chainregulation in disease: downquantification method: spectral counting
A0391 ATP5J_HUMANATP5J, ATP5A, ATPMATP synthase coupling factor 6regulation in disease: downquantification method: spectral counting
A0400 VATB2_HUMANATP6V1B2, ATP6B2, VPP3Vacuolar ATP synthase subunit Bregulation in disease: downquantification method: spectral counting
A0417 CAZA2_HUMANCAPZA2F-actin capping protein alpha-2 subunitregulation in disease: upquantification method: spectral counting
A0419XGELS_HUMANGSNGelsolin precursorregulation in disease: upquantification method: spectral counting
A0427 KPYR_HUMANPKLR, PK1, PKLPyruvate kinaseregulation in disease: downquantification method: spectral counting
A0429XACON_HUMANACO2Aconitate hydrataseregulation in disease: downquantification method: spectral counting
A0432 PRDX6_HUMANPRDX6, AOP2Peroxiredoxin 6regulation in disease: downquantification method: spectral counting
A0451 GRP78_HUMANHSPA5, GRP78Heat shock 70kDa protein 5regulation in disease: downquantification method: spectral counting
A0452 CALX_HUMANCANXCalnexin precursorregulation in disease: upquantification method: spectral counting
A0467 1433B_HUMANYWHAB14-3-3 protein beta/alpharegulation in disease: upquantification method: spectral counting
A0492XSTIP1_HUMANSTIP1Stress-induced-phosphoprotein 1regulation in disease: downquantification method: spectral counting
A0496 GGT1_HUMANGGT1, GGT, GTTGamma-glutamyltranspeptidase 1 precursorregulation in disease: downquantification method: spectral counting
A0524 PROF1_HUMANPFN1Profilin Iregulation in disease: upquantification method: spectral counting
A0537XANXA2_HUMANANXA2, ANX2, ANX2L4Annexin A2regulation in disease: upquantification method: spectral counting
A0567 GDIA_HUMANGDI1, GDIL, OPHN2Rab GDP dissociation inhibitor alpharegulation in disease: downquantification method: spectral counting
A0631 C1QBP_HUMANC1QBP, GC1QBP, HABP1Complement component 1regulation in disease: downquantification method: spectral counting
A0647XANXA1_HUMANANXA1, ANX1, LPC1Annexin A1regulation in disease: upquantification method: spectral counting
A0660XACTZ_HUMANACTR1A, CTRN1Alpha-centractinregulation in disease: downquantification method: spectral counting
A0777 XRCC5_HUMANXRCC5, G22P2, KARP-1X-ray repair cross-complementing protein 5regulation in disease: upquantification method: spectral counting
A0778 MAP4_HUMANMAP4Microtubule-associated protein 4regulation in disease: upquantification method: spectral counting
A0806 NHRF1_HUMANSLC9A3R1, NHERF, NHERF1Ezrin-radixin-moesin binding phosphoprotein-50regulation in disease: downquantification method: spectral counting
A0850XVIME_HUMANVIMVimentinregulation in disease: upquantification method: spectral counting
A0907 1433T_HUMANYWHAQ14-3-3 protein tauregulation in disease: upquantification method: spectral counting
A0971 COX5B_HUMANCOX5BCytochrome c oxidase polypeptide Vbregulation in disease: downquantification method: spectral counting
A0999 COF1_HUMANCFL1, CFLCofilinregulation in disease: upquantification method: spectral counting
A1021 CSRP1_HUMANCSRP1, CSRP, CYRPCysteine-rich protein 1regulation in disease: upquantification method: spectral counting
A1023XLPP_HUMANLPPLipoma preferred partnerregulation in disease: upquantification method: spectral counting
A1035XROA1_HUMANHNRPA1, HNRNPA1Heterogeneous nuclear ribonucleoprotein A1regulation in disease: upquantification method: spectral counting
A1082XGGT5_HUMANGGT5, GGTLA1Gamma-glutamyltransferase 5 precursorregulation in disease: upquantification method: spectral counting
A1133XSRSF1_HUMANSFRS1, SRSF1, ASFSerine/arginine-rich splicing factor 1regulation in disease: downquantification method: spectral counting
A1134XHNRPU_HUMANHNRNPU, HNRPU, SAFAHeterogenous nuclear ribonucleoprotein Uregulation in disease: upquantification method: spectral counting
A1136 ROA2_HUMANHNRNPA2B1, HNRPA2B1Heterogeneous nuclear ribonucleoproteins A2/B1regulation in disease: upquantification method: spectral counting
A1177 A2MG_HUMANA2M, CPAMD5, FWP007Alpha-2-macroglobulin precursorregulation in disease: upquantification method: spectral counting
A1215XGANAB_HUMANGANAB, G2ANNeutral alpha-glucosidase ABregulation in disease: downquantification method: spectral counting
A1222XRL5_HUMANRPL5, MSTP03060S ribosomal protein L5regulation in disease: downquantification method: spectral counting
A1292XUBE2N_HUMANUBE2N, BLUUbiquitin-conjugating enzyme E2 Nregulation in disease: downquantification method: spectral counting
A1312 PARP1_HUMANPARP1, ADPRT, PPOLPoly [ADP]-ribose polymerase-1regulation in disease: upquantification method: spectral counting
A1328 PEBP1_HUMANPEBP1, PBP, PEBPPhosphatidylethanolamine-binding protein 1regulation in disease: downquantification method: spectral counting
A1391 EHD2_HUMANEHD2, PAST2EH-domain containing protein 2regulation in disease: upquantification method: spectral counting
A1423XCO6A3_HUMANCOL6A3Collagen alpha 3(VI) chain precursorregulation in disease: upquantification method: spectral counting
A1466XFINC_HUMANFN1, FNFibronectinregulation in disease: upquantification method: spectral counting
A1468XPLMN_HUMANPLGPlasminogen precursorregulation in disease: upquantification method: spectral counting
A1471XVTNC_HUMANVTNVitronectin precursorregulation in disease: upquantification method: spectral counting
A1491XCO1A1_HUMANCOL1A1Collagen alpha-1(I) chainregulation in disease: upquantification method: spectral counting
A1492XCO1A2_HUMANCOL1A2Collagen alpha 2(I) chain precursorregulation in disease: upquantification method: spectral counting
A1493 FIBB_HUMANFGBFibrinogen beta chain precursorregulation in disease: upquantification method: spectral counting
A1508 LAMB1_HUMANLAMB1Laminin subunit beta-1regulation in disease: upquantification method: spectral counting
A1517XLAMB2_HUMANLAMB2, LAMSLaminin beta-2 chain precursorregulation in disease: upquantification method: spectral counting
A1518XLAMC1_HUMANLAMC1, LAMB2Laminin gamma-1 chain precursorregulation in disease: upquantification method: spectral counting
A1525 TENA_HUMANTNC, HXBTenascin precursorregulation in disease: upquantification method: spectral counting
A1528 ITA6_HUMANITGA6Integrin alpha-6regulation in disease: downquantification method: spectral counting
A154A TINAL_HUMANTINAGL1, GIS5, LCN7Tubulointerstitial nephritis antigen-related protein precursorregulation in disease: upquantification method: spectral counting
A1560 LAMA5_HUMANLAMA5Laminin subunit alpha-5regulation in disease: upquantification method: spectral counting
A156CXMVP_HUMANMVP, LRPMajor vault proteinregulation in disease: downquantification method: spectral counting
A1581XALBU_HUMANALB, GIG20, GIG42Serum albumin precursorregulation in disease: upquantification method: spectral counting
A1585XNID1_HUMANNID1, NIDNidogen-1regulation in disease: upquantification method: spectral counting
A1591XIC1_HUMANSERPING1, C1IN, C1NHSerine/cysteine proteinase inhibitor clade G member 1regulation in disease: upquantification method: spectral counting
A1598XCO3_HUMANC3, CPAMD1Complement C3 precursorregulation in disease: upquantification method: spectral counting
A1599XCFAH_HUMANCFH, HF, HF1Complement factor H precursorregulation in disease: upquantification method: spectral counting
A1609 CALR_HUMANCALR, CRTCCalreticulin precursorregulation in disease: upquantification method: spectral counting
A1611XHRG_HUMANHRGHistidine-rich glycoprotein precursorregulation in disease: upquantification method: spectral counting
A1616 CO5_HUMANC5, CPAMD4Complement C5 precursorregulation in disease: upquantification method: spectral counting
A1623 CO6_HUMANC6Complement component C6regulation in disease: upquantification method: spectral counting
A1628 CO9_HUMANC9Complement component C9 precursorregulation in disease: upquantification method: spectral counting
A1631XHPT_HUMANHPHaptoglobin precursorregulation in disease: upquantification method: spectral counting
A1675 FBLN1_HUMANFBLN1, PP213Fibulin-1 precursorregulation in disease: upquantification method: spectral counting
A1702XANGT_HUMANAGT, SERPINA8Angiotensinogenregulation in disease: upquantification method: spectral counting
A1714 APOB_HUMANAPOBApolipoprotein B-100 precursorregulation in disease: upquantification method: spectral counting
A172C MYO1C_HUMANMYO1CUnconventional myosin-Icregulation in disease: upquantification method: spectral counting
A1733 PDIA1_HUMANP4HB, ERBA2L, PDIProtein disulfide isomerase precursorregulation in disease: upquantification method: spectral counting
A1742 HBB_HUMANHBB, beta-globinHemoglobin beta chainregulation in disease: downquantification method: spectral counting
A1820 EF1A1_HUMANEEF1A1, EEF1A, EF1AElongation factor 1-alpha 1regulation in disease: downquantification method: spectral counting
A1849 TENX_HUMANTNXB, HXBL, TNXTenascin-Xregulation in disease: upquantification method: spectral counting
A1923 ALDOA_HUMANALDOA, ALDAFructose-bisphosphate aldolase Aregulation in disease: upquantification method: spectral counting
A1925XK6PL_HUMANPFKLPhosphofructokinaseregulation in disease: downquantification method: spectral counting
A1949 GSTA1_HUMANGSTA1, GST2Glutathione S-transferase A1regulation in disease: downquantification method: spectral counting
A1952 GSTK1_HUMANGSTK1, HDCMD47PGlutathione S-transferaseregulation in disease: downquantification method: spectral counting
A1956 GSTM3_HUMANGSTM3, GST5Glutathione S-transferase Mu 3regulation in disease: downquantification method: spectral counting
A195AXZA2G_HUMANAZGP1, ZAG, ZNGP1Zinc-alpha-2-glycoprotein precursorregulation in disease: upquantification method: spectral counting
A1968 EF1G_HUMANEEF1G, EF1G, PRO1608Elongation factor 1-gammaregulation in disease: downquantification method: spectral counting
A2003 HS90B_HUMANHSP90AB1, HSP90B, HSPC2Heat shock protein 90kDa alpha (cytosolic)regulation in disease: downquantification method: spectral counting
A2004XENPL_HUMANHSP90B1, GRP94, TRA1Endoplasmin precursorregulation in disease: upquantification method: spectral counting
A2006 HSP72_HUMANHSPA2Heat shock-related 70 kDa protein 2regulation in disease: downquantification method: spectral counting
A2008 HS71L_HUMANHSPA1LHeat shock 70 kDa protein 1-HOMregulation in disease: upquantification method: spectral counting
A2009 HSP76_HUMANHSPA6, HSP70B'Heat shock 70 kDa protein 6regulation in disease: downquantification method: spectral counting
A2010XGRP75_HUMANHSPA9, GRP75, HSPA9BStress-70 proteinregulation in disease: downquantification method: spectral counting
A2114XSC31A_HUMANSEC31A, SEC31L1, HSPC275Protein transport protein Sec31Aregulation in disease: downquantification method: spectral counting
A2143 COR1A_HUMANCORO1A, CORO1Coronin-like protein p57regulation in disease: upquantification method: spectral counting
A2331 MYH11_HUMANMYH11, SMMHCMyosin heavy chainregulation in disease: upquantification method: spectral counting
A250C NUCB1_HUMANNUCB1, NUC, CALNUCNucleobindin 1 precursorregulation in disease: downquantification method: spectral counting
A2536XNUCL_HUMANNCLNucleolinregulation in disease: upquantification method: spectral counting
A2583XSRSF7_HUMANSFRS7, SRSF7, 9g8Splicing factorregulation in disease: downquantification method: spectral counting
A2584 SRSF3_HUMANSFRS3, SRP20, SRSF3Serine/arginine-rich splicing factor 3regulation in disease: downquantification method: spectral counting
A2591XLA_HUMANSSB, SS-B/LaLupus La proteinregulation in disease: upquantification method: spectral counting
A304C QCR6_HUMANUQCRHUbiquinol-cytochrome C reductase complex 11 kDa proteinregulation in disease: downquantification method: spectral counting
A3166 MYH9_HUMANMYH9Myosin heavy chain 9regulation in disease: upquantification method: spectral counting
A318DXECHD3_HUMANECHDC3, PP1494, PP8332Enoyl coenzyme A hydratase domain containing 3regulation in disease: downquantification method: spectral counting
A3531XKTN1_HUMANKTN1, CG1, PDIA6Kinectinregulation in disease: downquantification method: spectral counting
A353CXRET4_HUMANRBP4, PRO2222, PRBPRetinol binding protein 4regulation in disease: upquantification method: spectral counting
A3540XTCPB_HUMANCCT2, 99D8.1, CCTBT-complex protein 1regulation in disease: downquantification method: spectral counting
A3542XTCPQ_HUMANCCT8, CCTQT-complex protein 1regulation in disease: downquantification method: spectral counting
A3543XTCPE_HUMANCCT5, CCTE, PNAS-102T-complex protein 1regulation in disease: downquantification method: spectral counting
A3548XPDIA6_HUMANP5, PDIA6, ERP5Protein disulfide isomerase A6 precursorregulation in disease: upquantification method: spectral counting
A3553 CN37_HUMANCNP2'regulation in disease: downquantification method: spectral counting
A3558 CHCH3_HUMANCHCHD3, MINOS3Coiled-coil-helix-coiled-coil-helix domain-containing protein 3 mitochondrial precursorregulation in disease: downquantification method: spectral counting
A3560XNDUAA_HUMANNDUFA10NADH-ubiquinone oxidoreductase 42 kDa subunitregulation in disease: downquantification method: spectral counting
A3561XNDUS1_HUMANNDUFS1, PRO1304NADH-ubiquinone oxidoreductase 75 kDa subunitregulation in disease: downquantification method: spectral counting
A3563 NDUA9_HUMANNDUFA9, NDUFS2LNADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9 mitochondrial precursorregulation in disease: downquantification method: spectral counting
A3564 NDUS3_HUMANNDUFS3NADH dehydrogenase [ubiquinone] iron-sulfur protein 3regulation in disease: downquantification method: spectral counting
A3598 ALDH2_HUMANALDH2, ALDMAldehyde dehydrogenaseregulation in disease: downquantification method: spectral counting
A3601 PCCA_HUMANPCCAPropionyl-CoA carboxylase alpha chainregulation in disease: downquantification method: spectral counting
A3602XPCCB_HUMANPCCBPropionyl-CoA carboxylase beta chainregulation in disease: downquantification method: spectral counting
A3603 MCCB_HUMANMCCC2, MCCBMethylcrotonyl-CoA carboxylase beta chainregulation in disease: downquantification method: spectral counting
A3604 MCCA_HUMANMCCC1, MCCAMethylcrotonyl-CoA carboxylase alpha chainregulation in disease: downquantification method: spectral counting
A3608 DPYL3_HUMANULIP, DPYSL3, LCRMPDihydropyrimidinase related protein-3regulation in disease: upquantification method: spectral counting
A3617 ENOB_HUMANENO3Beta enolaseregulation in disease: upquantification method: spectral counting
A3653XDDX3X_HUMANDDX3X, DBX, DDX3ATP-dependent RNA helicase DDX3Xregulation in disease: downquantification method: spectral counting
A3660XIDHP_HUMANIDH2, IDH, IDPIsocitrate dehydrogenase [NADP]regulation in disease: downquantification method: spectral counting
A3662XPYC_HUMANPCPyruvate carboxylaseregulation in disease: downquantification method: spectral counting
A3664 ODO1_HUMANOGDH2-oxoglutarate dehydrogenase E1 componentregulation in disease: downquantification method: spectral counting
A3665 OGDHL_HUMANOGDHL2-oxoglutarate dehydrogenase E1 component-likeregulation in disease: downquantification method: spectral counting
A3671 GLSK_HUMANGLS, GLS1Glutaminaseregulation in disease: downquantification method: spectral counting
A3672 AOFA_HUMANMAOAAmine oxidase [flavin-containing] Aregulation in disease: downquantification method: spectral counting
A3673 AOFB_HUMANMAOBAmine oxidase [flavin-containing] Bregulation in disease: downquantification method: spectral counting
A3674 DLDH_HUMANDLD, GCSL, LADDihydrolipoyl dehydrogenaseregulation in disease: downquantification method: spectral counting
A3676 QCR1_HUMANUQCRC1Ubiquinol-cytochrome C reductase complex core protein Iregulation in disease: downquantification method: spectral counting
A3677XQCR2_HUMANUQCRC2Cytochrome B-C1 complex subunit 2regulation in disease: downquantification method: spectral counting
A3680XDHE3_HUMANGLUD1, GLUDGlutamate dehydrogenase 1regulation in disease: downquantification method: spectral counting
A3682 ODO2_HUMANDLST, DLTS, E2Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complexregulation in disease: downquantification method: spectral counting
A3683 ECHA_HUMANHADHA, HADHTrifunctional enzyme alpha subunitregulation in disease: downquantification method: spectral counting
A3684 ECHB_HUMANHADHB, MSTP029Trifunctional enzyme beta subunitregulation in disease: downquantification method: spectral counting
A3685 ODPA_HUMANPDHA1, PHE1A, PDHA1/LOC79064Pyruvate dehydrogenase E1 component alpha subunitregulation in disease: downquantification method: spectral counting
A3688 CISY_HUMANCSCitrate synthaseregulation in disease: downquantification method: spectral counting
A3694 THIL_HUMANACAT1, ACAT, MATAcetyl-CoA acetyltransferaseregulation in disease: downquantification method: spectral counting
A3695 THIC_HUMANACAT2, ACTLCytosolic acetoacetyl-coenzyme A thiolaseregulation in disease: upquantification method: spectral counting
A3696 MDHM_HUMANMDH2Malate dehydrogenaseregulation in disease: downquantification method: spectral counting
A3698 CY1_HUMANCYC1Cytochrome c1regulation in disease: downquantification method: spectral counting
A369C RRBP1_HUMANRRBP1Ribosome-binding protein 1regulation in disease: upquantification method: spectral counting
A371E TAGL2_HUMANTAGLN2, CDABP0035Transgelin 2regulation in disease: upquantification method: spectral counting
A3747XCMC2_HUMANSLC25A13, ARALAR2Calcium-binding mitochondrial carrier protein Aralar2regulation in disease: downquantification method: spectral counting
A3776 MPCP_HUMANSLC25A3, PHCSolute carrier family 25 member 3regulation in disease: downquantification method: spectral counting
A3781XAIFM1_HUMANPDCD8, AIFM1, AIFProgrammed cell death protein 8regulation in disease: downquantification method: spectral counting
A3787XK1C19_HUMANKRT19, K19Keratinregulation in disease: upquantification method: spectral counting
A3788 SND1_HUMANSND1, TDRD11Staphylococcal nuclease domain containing protein 1regulation in disease: downquantification method: spectral counting
A3792 HNRPM_HUMANHNRNPM, HNRPM, NAGR1Heterogeneous nuclear ribonucleoprotein Mregulation in disease: upquantification method: spectral counting
A3793 PHB_HUMANPHBProhibitinregulation in disease: downquantification method: spectral counting
A3795 PURA_HUMANPURA, PUR1Transcriptional activator protein PUR-alpharegulation in disease: upquantification method: spectral counting
A3807 RLA0_HUMANRPLP060S acidic ribosomal protein P0regulation in disease: upquantification method: spectral counting
A3811 RL7A_HUMANRPL7A, SURF-3, SURF360S ribosomal protein L7aregulation in disease: upquantification method: spectral counting
A3812 RL8_HUMANRPL860S ribosomal protein L8regulation in disease: downquantification method: spectral counting
A3818 RS4X_HUMANRPS4X, CCG2, RPS440S ribosomal protein S4regulation in disease: upquantification method: spectral counting
A3849 K2C1_HUMANKRT1, KRTAKeratinregulation in disease: upquantification method: spectral counting
A3865 E41L3_HUMANEPB41L3, DAL1Band 4.1-like protein 3regulation in disease: downquantification method: spectral counting
A3873XANK2_HUMANANK2Ankyrin 2regulation in disease: downquantification method: spectral counting
A3909 VPS35_HUMANVPS35, MEM3Vacuolar protein sorting-associated protein 35regulation in disease: downquantification method: spectral counting
A3913 NIPS2_HUMANGBAS, NIPSNAP2Protein NIPSNAP homolog 2regulation in disease: downquantification method: spectral counting
A3914XNIPS1_HUMANNIPSNAP1NipSnap1 proteinregulation in disease: downquantification method: spectral counting
A3927XPICAL_HUMANPICALM, CALMPhosphatidylinositol-binding clathrin assembly proteinregulation in disease: upquantification method: spectral counting
A3942 STML2_HUMANSTOML2, SLP2, HSPC108Membrane associated protein SLP-2regulation in disease: downquantification method: spectral counting
A3949 MTCH2_HUMANMTCH2, MIMP, HSPC032Mitochondrial carrier homolog 2regulation in disease: downquantification method: spectral counting
A3961 MYH10_HUMANMYH10, SmembMyosin-10regulation in disease: upquantification method: spectral counting
A3967XKINH_HUMANKIF5B, KNS, KNS1Kinesin family member 5Bregulation in disease: downquantification method: spectral counting
A3973 IMMT_HUMANIMMT, HMP, PIG4Mitochondrial inner membrane proteinregulation in disease: downquantification method: spectral counting
A3999 LPPRC_HUMANLRPPRC, LRP130Leucine-rich PPR-motif containing proteinregulation in disease: downquantification method: spectral counting
A4004 LETM1_HUMANLETM1Leucine zipper-EF-hand containing transmembrane protein 1regulation in disease: downquantification method: spectral counting
A4146XLAP2A_HUMANTMPO, LAP2Thymopoietinregulation in disease: upquantification method: spectral counting
A424AXFHL1_HUMANFHL1, SLIM1Skeletal muscle LIM-protein 1regulation in disease: upquantification method: spectral counting
A4267XABCE1_HUMANABCE1, RLI, RNASEL1ATP-binding cassette sub-family E member 1regulation in disease: downquantification method: spectral counting
A4317 ERP29_HUMANERP29, ERP28Endoplasmic reticulum resident protein 29regulation in disease: downquantification method: spectral counting
A4406 TRAP1_HUMANTRAP1, HSP75Heat shock protein 75 kDaregulation in disease: downquantification method: spectral counting
A4446XCLIC4_HUMANCLIC4Chloride intracellular channel protein 4regulation in disease: downquantification method: spectral counting
A4595 BGH3_HUMANTGFBI, BIGH3Transforming growth factor-beta induced protein IG-H3 precursorregulation in disease: upquantification method: spectral counting
A4634XCAPG_HUMANCAPG, AFCP, MCPGelsolin-like capping proteinregulation in disease: upquantification method: spectral counting
A4636 CAZA1_HUMANCAPZA1F-actin capping protein alpha-1 subunitregulation in disease: upquantification method: spectral counting
A4685 CNN1_HUMANCNN1Calponin H1regulation in disease: upquantification method: spectral counting
A468AXH10_HUMANH1F0, H1FVHistone H1.0regulation in disease: downquantification method: spectral counting
A4709XCOEA1_HUMANCOL14A1, UNDCollagen alpha-1(XIV) chain precursorregulation in disease: upquantification method: spectral counting
A483D GBP1_HUMANGBP1Interferon-induced guanylate-binding protein 1regulation in disease: upquantification method: spectral counting
A491A H2AV_HUMANH2AFV, H2AVHistone H2A.F/Z variantregulation in disease: upquantification method: spectral counting
A4941 LG3BP_HUMANLGALS3BP, M2BPGalectin-3-binding protein precursorregulation in disease: upquantification method: spectral counting
A4951XLUM_HUMANLUM, LDC, SLRR2DLumican precursorregulation in disease: upquantification method: spectral counting
A5008XNID2_HUMANNID2Nidogen-2regulation in disease: upquantification method: spectral counting
A5069 PDLI1_HUMANPDLIM1, CLIM1, CLP36PDZ and LIM domain protein 1regulation in disease: upquantification method: spectral counting
A5085 PLSI_HUMANPLS1Plastin 1regulation in disease: upquantification method: spectral counting
A5086XPLSL_HUMANLCP1, PLS2Plastin-2regulation in disease: upquantification method: spectral counting
A5096 PRELP_HUMANPRELP, SLRR2A, MST161Prolargin precursorregulation in disease: upquantification method: spectral counting
A5170XSYNP2_HUMANSYNPO2, MYOPODINSynaptopodin 2regulation in disease: upquantification method: spectral counting
A5180 TBA1C_HUMANTUBA1C, TUBA6Tubulin alpha-1C chainregulation in disease: upquantification method: spectral counting
A5191XTBB4B_HUMANTUBB2C, TUBB4B, TUBB2Tubulin beta-2 chainregulation in disease: downquantification method: spectral counting
A5193XTBB4A_HUMANTUBB4, TUBB4A, TUBB5Tubulin beta-4 chainregulation in disease: downquantification method: spectral counting
A5224 TPM4_HUMANTPM4Tropomyosin alpha 4 chainregulation in disease: downquantification method: spectral counting
A5242 VILI_HUMANVIL1, VILVillin 1regulation in disease: downquantification method: spectral counting
A5398 MSTN1_HUMANMUSTN1Muscoskeletal embryonic nuclear protein 1regulation in disease: upquantification method: spectral counting
A551A HNRH1_HUMANHNRPH1, HNRNPH1, HNRPHHeterogeneous nuclear ribonucleoprotein Hregulation in disease: upquantification method: spectral counting
A552A HNRH2_HUMANHNRNPH2, FTP3, HNRPH2Heterogeneous nuclear ribonucleoprotein H2regulation in disease: upquantification method: spectral counting
A557A HNRPF_HUMANHNRNPF, HNRPFHeterogeneous nuclear ribonucleoprotein Fregulation in disease: upquantification method: spectral counting
A558A HNRPL_HUMANHNRNPL, HNRPLHeterogeneous nuclear ribonucleoprotein Lregulation in disease: upquantification method: spectral counting
A5625XA1AG1_HUMANORM1, AGP1, ORM2Alpha-1-acid glycoprotein 1 precursorregulation in disease: upquantification method: spectral counting
A5635 AATC_HUMANGOT1, GIG18Aspartate aminotransferaseregulation in disease: downquantification method: spectral counting
A5651 AOC1_HUMANABP1, AOC1, DAO1Amiloride-sensitive amine oxidase [copper-containing] precursorregulation in disease: downquantification method: spectral counting
A5656XACADS_HUMANACADSAcyl-CoA dehydrogenaseregulation in disease: downquantification method: spectral counting
A5657 ACADV_HUMANACADVL, VLCADAcyl-CoA dehydrogenaseregulation in disease: downquantification method: spectral counting
A5659 ACD10_HUMANACAD10Acyl-CoA dehydrohenase family member 10regulation in disease: downquantification method: spectral counting
A5661 ACDSB_HUMANACADSBAcyl-CoA dehydrogenaseregulation in disease: downquantification method: spectral counting
A5670 ACOC_HUMANACO1, IRP1, IREB1Iron-responsive element binding protein 1regulation in disease: downquantification method: spectral counting
A5679 ACOX1_HUMANACOX1, ACOXAcyl-coenzyme A oxidase 1regulation in disease: downquantification method: spectral counting
A5687 ACS2B_HUMANACSM2B, ACSM2, HYST1046Acyl-CoA synthetase medium chain family member 2Bregulation in disease: downquantification method: spectral counting
A5690 ACSF2_HUMANACSF2, UNQ493/PRO1009, UNQ493Acyl-CoA synthetase family member 2regulation in disease: downquantification method: spectral counting
A5700 ACSS3_HUMANACSS3Acyl-CoA synthetase short-chain family member 3 mitochondrialregulation in disease: downquantification method: spectral counting
A5703 ACY1_HUMANACY1, ABHD14A-ACY1Aminoacylase-1regulation in disease: downquantification method: spectral counting
A5727 ADH1B_HUMANADH1B, ADH2Alcohol dehydrogenase beta chainregulation in disease: upquantification method: spectral counting
A5748 AGT2_HUMANAGXT2, AGT2Alanine--glyoxylate aminotransferase 2regulation in disease: downquantification method: spectral counting
A5750 AK1A1_HUMANAKR1A1, ALDR1, ALRAlcohol dehydrogenase [NADP+]regulation in disease: downquantification method: spectral counting
A5755 AK1C3_HUMANAKR1C3, DDH1, HSD17B5Aldo-keto reductase family 1 member C3regulation in disease: downquantification method: spectral counting
A5766 AL4A1_HUMANALDH4A1, ALDH4, P5CDHDelta-1-pyrroline-5-carboxylate dehydrogenaseregulation in disease: downquantification method: spectral counting
A5767 AL7A1_HUMANALDH7A1, ATQ1Aldehyde dehydrogenase family 7 member A1regulation in disease: downquantification method: spectral counting
A5768 AL8A1_HUMANALDH8A1, ALDH12Aldehyde dehydrogenase 12regulation in disease: downquantification method: spectral counting
A5769 AL9A1_HUMANALDH9A1, ALDH4, ALDH7Aldehyde dehydrogenase 9A1regulation in disease: downquantification method: spectral counting
A5788XAMACR_HUMANAMACRAlpha-methylacyl-CoA racemaseregulation in disease: downquantification method: spectral counting
A5800 AMPN_HUMANCD13, ANPEP, APNAminopeptidase Nregulation in disease: downquantification method: spectral counting
A5824 ARK72_HUMANAKR7A2, AFAR, AFAR1Aflatoxin B1 aldehyde reductase 1regulation in disease: upquantification method: spectral counting
A5825 ARK73_HUMANAKR7A3, AFAR2Aflatoxin B1 aldehyde reductase 2regulation in disease: downquantification method: spectral counting
A5926XBHMT1_HUMANBHMTBetaine-homocysteine S-methyltransferase 1regulation in disease: downquantification method: spectral counting
A5927 BHMT2_HUMANBHMT2Betaine-homocysteine methyltransferase 2regulation in disease: downquantification method: spectral counting
A5937 BPHL_HUMANBPHL, MCNAABiphenyl hydrolase-like proteinregulation in disease: downquantification method: spectral counting
A5957 CACP_HUMANCRAT, CAT1Carnitine O-acetyltransferaseregulation in disease: downquantification method: spectral counting
A5960XCAH12_HUMANCA12Carbonic anhydrase 12regulation in disease: downquantification method: spectral counting
A5964XCAH2_HUMANCA2Carbonic anhydrase 2regulation in disease: downquantification method: spectral counting
A597A ILF3_HUMANILF3, DRBF, MPHOSPH4Interleukin enhancer-binding factor 3regulation in disease: upquantification method: spectral counting
A5981 CATA_HUMANCATCatalaseregulation in disease: downquantification method: spectral counting
A5982XCATB_HUMANCTSB, CPSB, APPSCathepsin B precursorregulation in disease: downquantification method: spectral counting
A5984XCATD_HUMANCTSD, CPSDCathepsin D precursorregulation in disease: upquantification method: spectral counting
A5993XCATZ_HUMANCTSZCathepsin Z precursorregulation in disease: downquantification method: spectral counting
A6009 CBR1_HUMANCBR1, CBR, CRNCarbonyl reductase [NADPH] 1regulation in disease: downquantification method: spectral counting
A6042 CERU_HUMANCPCeruloplasmin precursorregulation in disease: upquantification method: spectral counting
A6048XCHDH_HUMANCHDHCholine dehydrogenaseregulation in disease: downquantification method: spectral counting
A6071 CK054_HUMANLP4947, PTD012Ester hydrolase C11ORF54regulation in disease: upquantification method: spectral counting
A6101XCOX5A_HUMANCOX5ACytochrome c oxidase polypeptide Varegulation in disease: downquantification method: spectral counting
A6213 CRYL1_HUMANCRYL1, CRYLambda-crystallin homologregulation in disease: downquantification method: spectral counting
A6256XDDAH2_HUMANDDAH2, DDAH, G6ANGregulation in disease: upquantification method: spectral counting
A6257 DDC_HUMANDDC, AADCAromatic-L-amino-acid decarboxylaseregulation in disease: downquantification method: spectral counting
A6308 DHB4_HUMANHSD17B4, EDH17B4Peroxisomal multifunctional enzyme type 2regulation in disease: downquantification method: spectral counting
A6314 DHPR_HUMANQDPR, DHPR, HDHPRDihydropteridine reductaseregulation in disease: downquantification method: spectral counting
A6319 DHSA_HUMANSDHA, SDH2, SDHFSuccinate dehydrogenase [ubiquinone flavoprotein subunit]regulation in disease: downquantification method: spectral counting
A6356 DPEP1_HUMANDPEP1, MDP, RDPMicrosomal dipeptidase precursorregulation in disease: downquantification method: spectral counting
A6366XDPP3_HUMANDPP3Dipeptidyl peptidase 3regulation in disease: upquantification method: spectral counting
A6367XDPP4_HUMANDPP4, ADCP2, CD26Dipeptidyl peptidase 4regulation in disease: downquantification method: spectral counting
A6408 ECHM_HUMANECHS1Enoyl-CoA hydrataseregulation in disease: downquantification method: spectral counting
A6409 ECHP_HUMANEHHADH, ECHDPeroxisomal bifunctional enzymeregulation in disease: downquantification method: spectral counting
A6411 ECI2_HUMANPECI, HCA64, ECI2Peroxisomal 3regulation in disease: downquantification method: spectral counting
A643CXTRFE_HUMANTF, PRO1400Serotransferrin precursorregulation in disease: upquantification method: spectral counting
A6457 EST2_HUMANCES2, ICE, CE-2Carboxylesterase 2 precursorregulation in disease: downquantification method: spectral counting
A6477 F16P1_HUMANFBP1, FBPFructose-1regulation in disease: downquantification method: spectral counting
A6483 FAAA_HUMANFAHFumarylacetoacetaseregulation in disease: downquantification method: spectral counting
A648CXTTHY_HUMANTTR, PALB, TBPATransthyretin precursorregulation in disease: upquantification method: spectral counting
A6527 FTCD_HUMANFTCDFormimidoyltransferase-cyclodeaminaseregulation in disease: downquantification method: spectral counting
A6534 FUMH_HUMANFHFumarate hydrataseregulation in disease: downquantification method: spectral counting
A6551 G6PI_HUMANGPIGlucose-6-phosphate isomeraseregulation in disease: downquantification method: spectral counting
A6557XGALK1_HUMANGALK1, GALKGalactokinaseregulation in disease: downquantification method: spectral counting
A6559XGALM_HUMANGALM, Ibd1, BLOCK25Aldose 1-epimeraseregulation in disease: downquantification method: spectral counting
A6572 GATM_HUMANGATM, AGATGlycine amidinotransferaseregulation in disease: downquantification method: spectral counting
A6573 GCDH_HUMANGCDHGlutaryl-CoA dehydrogenaseregulation in disease: downquantification method: spectral counting
A6614 GLYAT_HUMANGLYAT, ACGNAT, CATGlycine N-acyltransferaseregulation in disease: downquantification method: spectral counting
A6615 GLYC_HUMANSHMT1, SHMTSerine hydroxymethyltransferase 1regulation in disease: downquantification method: spectral counting
A6617 GLYL1_HUMANGLYATL1, GNAT, GATF-CGlycine-N-acyltransferase-like protein 1regulation in disease: downquantification method: spectral counting
A6619XGLYM_HUMANSHMT2Serine hydroxymethyltransferaseregulation in disease: downquantification method: spectral counting
A6629XGNPI1_HUMANGNPDA1, GNPI, HLNGlucosamine-6-phosphate isomeraseregulation in disease: downquantification method: spectral counting
A6644 GPX3_HUMANGPX3, GPXPGlutathione peroxidase 3regulation in disease: downquantification method: spectral counting
A6658 GRHPR_HUMANGRHPR, GLXR, MSTP035Glyoxylate reductaseregulation in disease: downquantification method: spectral counting
A6692XHCD2_HUMANHSD17B10, ERAB, HADH23-hydroxyacyl-CoA dehydrogenase type 2regulation in disease: downquantification method: spectral counting
A6693XHCDH_HUMANHADH, HAD, HADHSCHydroxyacyl-coenzyme A dehydrogenaseregulation in disease: downquantification method: spectral counting
A6721 HEXB_HUMANHEXB, HCC7Beta-hexosaminidase beta chain precursorregulation in disease: upquantification method: spectral counting
A6725 HIBCH_HUMANHIBCH3-Hydroxyisobutyryl-coenzyme A hydrolaseregulation in disease: downquantification method: spectral counting
A6738 HOGA1_HUMANHOGA1, DHDPSLDihydrodipicolinate synthetase-likeregulation in disease: downquantification method: spectral counting
A6750 HSDL2_HUMANHSDL2Hydroxysteroid dehydrogenase-like protein 2regulation in disease: downquantification method: spectral counting
A6767 HYES_HUMANEPHX2, CYTEPOXEpoxide hydrolase 2regulation in disease: downquantification method: spectral counting
A678D LRC47_HUMANLRRC47Leucine-rich repeat-containing protein 47regulation in disease: downquantification method: spectral counting
A6805 IPYR2_HUMANPPA2, HSPC124, SID6-306Inorganic pyrophosphatase 2regulation in disease: downquantification method: spectral counting
A6824 KAD3_HUMANAK3, AK3L1, AK6GTP:AMP phosphotransferase mitochondrialregulation in disease: downquantification method: spectral counting
A6825XKAD4_HUMANAK3L1, AK3L2, AK3Adenylate kinase isoenzyme 4regulation in disease: downquantification method: spectral counting
A6849 KHK_HUMANKHKKetohexokinaseregulation in disease: downquantification method: spectral counting
A6888 LDHD_HUMANLDHDD-lactate dehydrogenaseregulation in disease: downquantification method: spectral counting
A6905XLKHA4_HUMANLTA4H, LTA4Leukotriene A-4 hydrolaseregulation in disease: upquantification method: spectral counting
A6910XLONM_HUMANLONP1, PRSS15Lon protease homologregulation in disease: downquantification method: spectral counting
A6940XM2GD_HUMANDMGDHDimethylglycine dehydrogenaseregulation in disease: downquantification method: spectral counting
A7051 MMSA_HUMANMMSADHA, ALDH6A1, MMSDHMethylmalonate-semialdehyde dehydrogenase [acylating]regulation in disease: downquantification method: spectral counting
A7149 NEP_HUMANMME, EPNNeprilysinregulation in disease: downquantification method: spectral counting
A7159 NIT2_HUMANNIT2, CUA002Omega-amidase NIT2regulation in disease: downquantification method: spectral counting
A7175 NQO2_HUMANNQO2, NMOR2NRH dehydrogenase [quinone] 2regulation in disease: downquantification method: spectral counting
A7306 PBLD_HUMANPBLD, MAWBPPhenazine biosynthesis-like domain-containing proteinregulation in disease: downquantification method: spectral counting
A7340XPDIA4_HUMANPDIA4, ERP70, ERP72Protein disulfide isomerase A4 precursorregulation in disease: upquantification method: spectral counting
A7357XPEPD_HUMANPEPD, PRDXaa-Pro dipeptidaseregulation in disease: downquantification method: spectral counting
A7369 PGES2_HUMANPTGES2, PGES2Prostaglandin E synthase 2regulation in disease: downquantification method: spectral counting
A7381 PGRP2_HUMANPGLYRP2, PGLYRPL, PGRPLN-acetylmuramoyl-L-alanine amidase precursorregulation in disease: upquantification method: spectral counting
A7383 PH4H_HUMANPAHPhenylalanine-4-hydroxylaseregulation in disease: downquantification method: spectral counting
A7390 PHS_HUMANPCBD1, DCOH, PCBDPterin-4-alpha-carbinolamine dehydrataseregulation in disease: downquantification method: spectral counting
A7518XPSA1_HUMANPSMA1, HC2, NUProteasome subunit alpha type 1regulation in disease: downquantification method: spectral counting
A7519 PSA2_HUMANPSMA2, HC3, PSC3Proteasome subunit alpha type 2regulation in disease: upquantification method: spectral counting
A7539 PTER_HUMANPTER, HPHRPPhosphotriesterase related proteinregulation in disease: downquantification method: spectral counting
A7661 DNPH1_HUMANDNPH1, RCLDeoxyribonucleoside 5'-monophosphate N-glycosidaseregulation in disease: downquantification method: spectral counting
A7722 RNH1_HUMANRNASEH1, RNH1Ribonuclease H1regulation in disease: upquantification method: spectral counting
A7725XRNT2_HUMANRNASET2, RNASE6PLRibonuclease 6 precursorregulation in disease: downquantification method: spectral counting
A7767 S27A2_HUMANSLC27A2, ACSVL1, FACVL1Very long-chain acyl-CoA synthetaseregulation in disease: downquantification method: spectral counting
A7776 SARDH_HUMANSARDH, DMGDHL1Sarcosine dehydrogenaseregulation in disease: downquantification method: spectral counting
A7793 SERA_HUMANPGDH3, PHGDHD-3-phosphoglycerate dehydrogenaseregulation in disease: downquantification method: spectral counting
A7819 SIAE_HUMANSIAE, YSG2, CSE-CSialate O-acetylesteraseregulation in disease: downquantification method: spectral counting
A7820 SIAS_HUMANNANS, SAS, HSPC269N-acetylneuraminate synthaseregulation in disease: upquantification method: spectral counting
A7842 SODC_HUMANSOD1Superoxide dismutase [Cu-Zn]regulation in disease: downquantification method: spectral counting
A7843XSODE_HUMANSOD3Extracellular superoxide dismutase [Cu-Zn] precursorregulation in disease: upquantification method: spectral counting
A7851 SPEB_HUMANAGMATAgmatinaseregulation in disease: downquantification method: spectral counting
A7863 SQRD_HUMANSQRDL, CGI-44, PRO1975Sulfide:quinone oxidoreductaseregulation in disease: downquantification method: spectral counting
A7900 SUCB2_HUMANSUCLG2Succinyl-CoA ligase [GDP-forming] beta-chainregulation in disease: downquantification method: spectral counting
A7930XSYQ_HUMANQARS, PRO2195Glutaminyl-tRNA synthetaseregulation in disease: downquantification method: spectral counting
A7976 THIK_HUMANACAA1, ACAA, PTHIO3-ketoacyl-CoA thiolaseregulation in disease: downquantification method: spectral counting
A7984 THTR_HUMANTSTThiosulfate sulfurtransferaseregulation in disease: downquantification method: spectral counting
A7989 TKT_HUMANTKT, TKT1Transketolaseregulation in disease: downquantification method: spectral counting
A8092XUBA1_HUMANUBA1, UBE1, A1S9TUbiquitin-activating enzyme E1regulation in disease: upquantification method: spectral counting
A809B APOA2_HUMANAPOA2Apolipoprotein A-II precursorregulation in disease: upquantification method: spectral counting
A810BXAPOA4_HUMANAPOA4, ApoA-IVApolipoprotein A-IV precursorregulation in disease: upquantification method: spectral counting
A8144 UCRI_HUMANUQCRFS1Ubiquinol-cytochrome C reductase iron-sulfur subunitregulation in disease: downquantification method: spectral counting
A815B APOD_HUMANAPODApolipoprotein D precursorregulation in disease: downquantification method: spectral counting
A8165 UGDH_HUMANGDH, ugd, UGDHUDP-glucose 6-dehydrogenaseregulation in disease: downquantification method: spectral counting
A8369XA1AT_HUMANA1A, SERPINA1, AATAlpha-1-antitrypsin precursorregulation in disease: upquantification method: spectral counting
A8420 ILEU_HUMANSERPINB1, ELANH2, MNEILeukocyte elastase inhibitorregulation in disease: upquantification method: spectral counting
A8616 DRA_HUMANHLA-DRA, HLA-DRA1HLA class II histocompatibility antigenregulation in disease: upquantification method: spectral counting
A8663XAPOH_HUMANAPOH, B2G1Beta-2-glycoprotein 1 precursorregulation in disease: upquantification method: spectral counting
A8694 CALU_HUMANCALUCalumenin precursorregulation in disease: upquantification method: spectral counting
A8783XFETUA_HUMANAHSG, FETUA, PRO2743Alpha-2-HS-glycoprotein precursorregulation in disease: upquantification method: spectral counting
A8804 GDIB_HUMANGDI2, RABGDIBRab GDP dissociation inhibitor betaregulation in disease: downquantification method: spectral counting
A887AXPTRF_HUMANPTRF, FKSG13Polymerase I and transcript release factorregulation in disease: upquantification method: spectral counting
A8960 PRS7_HUMANPSMC2, MSS126S protease regulatory subunit 7regulation in disease: downquantification method: spectral counting
A8961XPRS8_HUMANPSMC5, SUG126S protease regulatory subunit 8regulation in disease: downquantification method: spectral counting
A9151 VWA1_HUMANVWA1, WARPVon Willebrand factor A domain-containing protein 1regulation in disease: upquantification method: spectral counting
A925BXCUBN_HUMANCUBN, IFCRCubilinregulation in disease: downquantification method: spectral counting
A931B CYC_HUMANCYCS, CYCCytochrome Cregulation in disease: downquantification method: spectral counting
A9532 PCBP2_HUMANPCBP2Poly(rC)-binding protein 2regulation in disease: upquantification method: spectral counting
A9580 RLA2_HUMANRPLP2, D11S2243E, RPP260S acidic ribosomal protein P2regulation in disease: upquantification method: spectral counting
A962B ETFB_HUMANETFB, FP585Electron transfer flavoprotein beta-subunitregulation in disease: downquantification method: spectral counting
A9732 NHRF3_HUMANPDZK1, CAP70, NHERF3PDZ domain containing-protein 1regulation in disease: downquantification method: spectral counting
A9737 PDLI2_HUMANPDLIM2, PP6345PDZ and LIM domain protein 2regulation in disease: downquantification method: spectral counting
A9987 MACD1_HUMANMACROD1, LRP16O-acetyl-ADP-ribose deacetylase MACROD1regulation in disease: downquantification method: spectral counting
BZ5EN ENSG00000200879SNORD14Esmall nucleolar RNAregulation in disease: upquantification method: spectral counting

Compile date 08-10-2018© iMODE-CKD consortium