CKDdb-logoCKDdb - Study ID Exp19845401

PubMed ID19845401
AuthorsGao BB, Phipps JA, Bursell D, Clermont AC, Feener EP.
TitleAngiotensin AT1 receptor antagonism ameliorates murine retinal proteome changes induced by diabetes.
JournalJ Proteome Res. 2009 Dec;8(12):5541-9.
AbstractDiabetic retinopathy is the most common microvascular complication caused by diabetes mellitus and is a leading cause of vision loss among working-age adults in developed countries. Understanding the effects of diabetes on the retinal proteome may provide insights into factors and mechanisms responsible for this disease. We have performed a comprehensive proteomic analysis and comparison of retina from C57BL/6 mice with 2 months of streptozotocin-induced diabetes and age-matched nondiabetic control mice. To explore the role of the angiotensin AT1 receptor in the retinal proteome in diabetes, a subgroup of mice were treated with the AT1 antagonist candesartan. We identified 1792 proteins from retinal lysates, of which 65 proteins were differentially changed more than 2-fold in diabetic mice compared with nondiabetic mice. A majority (72%) of these protein changes were normalized by candesartan treatment. Most of the significantly changed proteins were associated with metabolism, oxidative phosphorylation, and apoptotic pathways. An analysis of the proteomics data revealed metabolic and apoptotic abnormalities in the retina from diabetic mice that were ameliorated with candesartan treatment. These results provide insight into the effects of diabetes on the retina and the role of the AT1 receptor in modulating this response.

Sample characteristics

SpeciesTissue / SourceCompartmentDiseaseNDetection method
Mus musculuseyesretinaDiabetes32LC-MS/MS

Sample description and preparation

N (case)21
N (control)11
Disease (case)diabetic retinopathy
Disease (control)healthy, intrap. inj. citrate buffer
Disease inductionintrap. inj. STZ (45 mg/kg)
Digestin-gel, trypsin
Separation1-DE

Molecule list

Molecule IDextExternal IDGeneNameSource accRegulation (case/control)Scores
A4730 CRBB2_MOUSECrybb2Beta-crystallin B2IPI:IPI00222211ratio: 0.32
A969F CRBA1_MOUSECryba1Beta-crystallin A1IPI:IPI00134845ratio: 0.19
A1481 HINT1_MOUSEHint1, Hint, PkciHistidine triad nucleotide-binding protein 1IPI:IPI00108189ratio: 0.46
A4962XMARCS_MOUSEMarcks, MacsMyristoylated alanine-rich C-kinase substrateIPI:IPI00229534ratio: 2.25
A975F CRBS_MOUSECrygsBeta-crystallin SIPI:IPI00130922ratio: 0.24
A9077 SUMO2_MOUSESumo2, Smt3a, Smt3h2Small ubiquitin-related modifier 2IPI:IPI00165706ratio: 2.51
A971F CRBA4_MOUSECryba4Beta-crystallin A4IPI:IPI00227782ratio: 0.15
A4729 CRBB1_MOUSECrybb1Beta-crystallin B1IPI:IPI00126051ratio: 0.22
A970F CRBA2_MOUSECryba2Beta-crystallin A2IPI:IPI00227849ratio: 0.38
A972F CRBB3_MOUSECrybb3Beta-crystallin B3IPI:IPI00122270ratio: 0.17
A3561XNDUS1_MOUSENdufs1NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrialIPI:IPI00308882ratio: 2.48
A1100 SMD1_MOUSESnrpd1Small nuclear ribonucleoprotein Sm D1IPI:IPI00322749ratio: 0.4
A6354 DOPD_MOUSEDdtD-dopachrome decarboxylaseIPI:IPI00230034ratio: 0.48
A0161 SYN1_MOUSESyn1, Syn-1Synapsin-1IPI:IPI00649886ratio: 2.03
A0755 PEA15_MOUSEPea15, Pea15aAstrocytic phosphoprotein PEA-15IPI:IPI00121013ratio: 0.38
A7663 RDH12_MOUSERdh12Retinol dehydrogenase 12IPI:IPI00227144ratio: 2.08
A9544XRL18_MOUSERpl1860S ribosomal protein L18IPI:IPI00555113ratio: 2.02
A900G IMPG1_MOUSEImpg1, SpacrInterphotoreceptor matrix proteoglycan 1IPI:IPI00788505ratio: 0.48
A4725 COTL1_MOUSECotl1, ClpCoactosin-like proteinIPI:IPI00132575ratio: 0.38
A2331 MYH11_MOUSEMyh11Myosin-11IPI:IPI00876408ratio: 5.53
A983F CRGB_MOUSECrygbGamma-crystallin BIPI:IPI00554941ratio: 0.26
A9106 THIO_MOUSETxn, Txn1ThioredoxinIPI:IPI00226993ratio: 0.43
A8962 PRVA_MOUSEPvalb, PvaParvalbumin alphaIPI:IPI00230766ratio: 0.37
A4627 CADM2_MOUSECadm2, Igsf4d, Necl3Cell adhesion molecule 2IPI:IPI00453537ratio: 0.38
A6264 DDX17_MOUSEDdx17Probable ATP-dependent RNA helicase DDX17IPI:IPI00396797ratio: 2.03
A6101XCOX5A_MOUSECox5aCytochrome c oxidase subunit 5A, mitochondrialIPI:IPI00120719ratio: 0.4
A0658 DCTN1_MOUSEDctn1Dynactin subunit 1IPI:IPI00115663ratio: 2.07
A0212 RP3A_MOUSERph3aRabphilin-3AIPI:IPI00111151ratio: 2.42
A3534 HS12A_MOUSEHspa12aHeat shock 70 kDa protein 12AIPI:IPI00279443ratio: 2.96
A0647XANXA1_MOUSEAnxa1, Anx1, Lpc-1Annexin A1IPI:IPI00230395ratio: 2.08
A200C NDUA8_MOUSENdufa8NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8IPI:IPI00120984ratio: 2.26
A159C MYG_MOUSEMbMyoglobinIPI:IPI00230760ratio: 0.17
A0092 41_MOUSEEpb41, Epb4.1Protein 4.1IPI:IPI00395157ratio: 2.16
A3584XFAS_MOUSEFasnFatty acid synthaseIPI:IPI00113223ratio: 2.12
A0534 GFAP_MOUSEGfapGlial fibrillary acidic proteinIPI:IPI00117042ratio: 0.08
A3952 SFXN3_MOUSESfxn3Sideroflexin-3IPI:IPI00126115ratio: 2.73
A3671 GLSK_MOUSEGls, Gls1Glutaminase kidney isoform, mitochondrialIPI:IPI00464317ratio: 2.56
A0405 VATF_MOUSEAtp6v1f, Atp6s14, VatfV-type proton ATPase subunit FIPI:IPI00315999ratio: 0.38
A6392XDUS3_MOUSEDusp3Dual specificity protein phosphatase 3IPI:IPI00110990ratio: 2.24
A372E TAGL3_MOUSETagln3, Np25Transgelin-3IPI:IPI00128986ratio: 2.38
A0436 MPP2_MOUSEMpp2, Dlgh2MAGUK p55 subfamily member 2IPI:IPI00125147ratio: 2.2
A5815 APEX1_MOUSEApex1, Ape, ApexDNA-(apurinic or apyrimidinic site) lyaseIPI:IPI00224152ratio: 2.06
A8926 PDE6D_MOUSEPde6dRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit deltaIPI:IPI00115190ratio: 0.36
A7919XSYG_MOUSEGarsGlycine--tRNA ligaseIPI:IPI00112555ratio: 2.05
A968A RU2A_MOUSESnrpa1U2 small nuclear ribonucleoprotein A'IPI:IPI00170008ratio: 2.49
F8572 A2AEN9Gm5938Protein Gm5938IPI:IPI00463193ratio: 0.26
A3806XIF4B_MOUSEEif4bEukaryotic translation initiation factor 4BIPI:IPI00221581ratio: 0.49
A019BXSMD2_MOUSESnrpd2Small nuclear ribonucleoprotein Sm D2IPI:IPI00119220ratio: 0.49
A3563 NDUA9_MOUSENdufa9NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrialIPI:IPI00120212ratio: 2.02
A4033 DMXL2_MOUSEDmxl2DmX-like protein 2IPI:IPI00605677ratio: 2.14
A3874 ANK3_MOUSEAnk3Ankyrin-3IPI:IPI00308750ratio: 2.04
A0261 PFKAM_MOUSEPfkm, Pfk-m, PfkaATP-dependent 6-phosphofructokinase, muscle typeIPI:IPI00331541ratio: 2.55
A370A EFTU_MOUSETufmElongation factor Tu, mitochondrialIPI:IPI00274407ratio: 2.23
A0508XAT2B2_MOUSEAtp2b2, Pmca2Plasma membrane calcium-transporting ATPase 2IPI:IPI00463671ratio: 2.38
A9543 RL17_MOUSERpl1760S ribosomal protein L17IPI:IPI00453768ratio: 2.26
A9769 API5_MOUSEApi5Apoptosis inhibitor 5IPI:IPI00754418ratio: 2.54
A3911 SNAG_MOUSENapg, SnapgGamma-soluble NSF attachment proteinIPI:IPI00109870ratio: 2.26
A3502 AAK1_MOUSEAak1AP2-associated protein kinase 1IPI:IPI00458612ratio: 3.28
A9587 RM12_MOUSEMrpl12, Rpml1239S ribosomal protein L12, mitochondrialIPI:IPI00118963ratio: 2.93
A021CXHEMO_MOUSEHpx, HpxnHemopexinIPI:IPI00128484ratio: 0.43
A1177 A2M_MOUSEA2m, PzpAlpha-2-macroglobulinIPI:IPI00624663ratio: 0.3
A740AXLSM8_MOUSELsm8, Naa38U6 snRNA-associated Sm-like protein LSm8IPI:IPI00263042ratio: 0.41
A0216XSLMAP_MOUSESlmap, SlapSarcolemmal membrane-associated proteinIPI:IPI00624363ratio: 3.57
A6840 KCY_MOUSECmpk1, Cmk, CmpkUMP-CMP kinaseIPI:IPI00331146ratio: 2.23
A1337XIF2A_MOUSEEif2s1, Eif2aEukaryotic translation initiation factor 2 subunit 1IPI:IPI00474446ratio: 2.38
A256E RPR1B_MOUSERprd1b, CreptRegulation of nuclear pre-mRNA domain-containing protein 1BIPI:IPI00338515ratio: 2.34
A9551XRL23A_MOUSERpl23a60S ribosomal protein L23aIPI:IPI00461456ratio: 3.09
A9997 MTFP1_MOUSEMtfp1, Mtp18Mitochondrial fission process protein 1IPI:IPI00315908ratio: 2
A287C PITM1_MOUSEPitpnm1, Dres9, Mpt1Membrane-associated phosphatidylinositol transfer protein 1IPI:IPI00136246ratio: 4.04
A024D CDV3_MOUSECdv3Protein CDV3IPI:IPI00187275ratio: 2.01
A7031XMIRO2_MOUSERhot2, Arht2Mitochondrial Rho GTPase 2IPI:IPI00473646ratio: 2.3
A553A D3Z3N4Hnrnph3Protein Hnrnph3IPI:IPI00816884ratio: 2.28
A452C S6A11_MOUSESlc6a11, Gabt3, Gabt4Sodium- and chloride-dependent GABA transporter 3IPI:IPI00136867ratio: 2.4
A3560XNDUAA_MOUSENdufa10NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrialIPI:IPI00116748ratio: 2.32
A3562 NDUS2_MOUSENdufs2NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrialIPI:IPI00128023ratio: 2.31
A4363 PFD2_MOUSEPfdn2, Pfd2Prefoldin subunit 2IPI:IPI00119545ratio: 2.44
A6375 DTD1_MOUSEDtd1, Hars2D-tyrosyl-tRNA(Tyr) deacylase 1IPI:IPI00133713ratio: 3.74
A6426 ENOPH_MOUSEEnoph1, MasaEnolase-phosphatase E1IPI:IPI00653664ratio: 2.08
A3286 LRC59_MOUSELrrc59Leucine-rich repeat-containing protein 59IPI:IPI00123281ratio: 2.02
A901BXCOPZ1_MOUSECopz1, CopzCoatomer subunit zeta-1IPI:IPI00139637ratio: 2.24
A9633XRS15A_MOUSERps15a40S ribosomal protein S15aIPI:IPI00230660ratio: 0.3
A6645 GPX41_MOUSEGpx4, GPx4Phospholipid hydroperoxide glutathione peroxidase, mitochondrialIPI:IPI00117281ratio: 2.68
A2562XRBM3_MOUSERbm3Putative RNA-binding protein 3IPI:IPI00130883ratio: 0.31
A802B AP3B2_MOUSEAp3b2AP-3 complex subunit beta-2IPI:IPI00420426ratio: 2.16
A6759 HUWE1_MOUSEHuwe1, Ureb1, MuleE3 ubiquitin-protein ligase HUWE1IPI:IPI00655012ratio: 2
A5683 APEH_MOUSEApehAcylamino-acid-releasing enzymeIPI:IPI00279218ratio: 0.47
A8763XEFHD2_MOUSEEfhd2, Sws1EF-hand domain-containing protein D2IPI:IPI00112223ratio: 2.69
A464A GTF2I_MOUSEGtf2i, Bap135, Diws1tGeneral transcription factor II-IIPI:IPI00113686ratio: 2.27
A4218 SMC1A_MOUSESmc1a, Sb1.8, Smc1Structural maintenance of chromosomes protein 1AIPI:IPI00123870ratio: 5.42
A0244 PSB4_MOUSEPsmb4, Lmp3Proteasome subunit beta type-4IPI:IPI00129512ratio: 2.32
A001I PTBP2_MOUSEPtbp2, Brptb, NptbPolypyrimidine tract-binding protein 2IPI:IPI00751759ratio: 2.56
A7121 NB5R3_MOUSECyb5r3, Dia1NADH-cytochrome b5 reductase 3IPI:IPI00121079ratio: 2.09
A0787XFKBP4_MOUSEFkbp4, Fkpb52Peptidyl-prolyl cis-trans isomerase FKBP4IPI:IPI00230139ratio: 2.51
A7492 PPME1_MOUSEPpme1, Pme1Protein phosphatase methylesterase 1IPI:IPI00415908ratio: 0.41
A5830 AS3MT_MOUSEAs3mt, Cyt19Arsenite methyltransferaseIPI:IPI00515140ratio: 2.07
A5694 ACSL3_MOUSEAcsl3, Acs3, Facl3Long-chain-fatty-acid--CoA ligase 3IPI:IPI00169772ratio: 2.95
A421A FA98B_MOUSEFam98bProtein FAM98BIPI:IPI00465946ratio: 2.08
A029D NAKD2_MOUSENadk2, Mnadk, Nadkd1NAD kinase 2, mitochondrialIPI:IPI00662342ratio: 2.14
A6960 MAOM_MOUSEMe2NAD-dependent malic enzyme, mitochondrialIPI:IPI00115977ratio: 2.04
A3788 SND1_MOUSESnd1Staphylococcal nuclease domain-containing protein 1IPI:IPI00123129ratio: 2.13
A2589 RALY_MOUSERaly, MercRNA-binding protein RalyIPI:IPI00130147ratio: 2.86
A4322XFKBP2_MOUSEFkbp2, Fkbp13Peptidyl-prolyl cis-trans isomerase FKBP2IPI:IPI00133948ratio: 0.21
A0029XANXA6_MOUSEAnxa6, Anx6Annexin A6IPI:IPI00310240ratio: 3.3
A033A PDCD6_MOUSEPdcd6, Alg2Programmed cell death protein 6IPI:IPI00121736ratio: 2.01
A681AXMECP2_MOUSEMecp2Methyl-CpG-binding protein 2IPI:IPI00131063ratio: 4.34
A8976XPTMA_MOUSEPtmaProthymosin alphaIPI:IPI00224784ratio: 0.14
A8968XPSMD3_MOUSEPsmd3, P91a, Tstap91a26S proteasome non-ATPase regulatory subunit 3IPI:IPI00314439ratio: 2.13
A5824 ARK72_MOUSEAkr7a2, Afar, Akr7a5Aflatoxin B1 aldehyde reductase member 2IPI:IPI00331490ratio: 2.81
A807CXAPOOL_MOUSEApool, Fam121aApolipoprotein O-likeIPI:IPI00112493ratio: 2.63
A0149XMYO5A_MOUSEMyo5a, DiluteUnconventional myosin-VaIPI:IPI00118120ratio: 2.55
A1964 GSTT1_MOUSEGstt1Glutathione S-transferase theta-1IPI:IPI00554933ratio: 2.1
A3951 SFXN1_MOUSESfxn1, FSideroflexin-1IPI:IPI00115454ratio: 3.19
A943B DYL2_MOUSEDynll2, Dlc2Dynein light chain 2, cytoplasmicIPI:IPI00132734ratio: 2.22
A637B TM109_MOUSETmem109Transmembrane protein 109IPI:IPI00153101ratio: 3.65
A0654 MARE2_MOUSEMapre2Microtubule-associated protein RP/EB family member 2IPI:IPI00403682ratio: 2.29
A3999 LPPRC_MOUSELrpprc, Lrp130Leucine-rich PPR motif-containing protein, mitochondrialIPI:IPI00420706ratio: 3.96
A8493XSPA3M_MOUSESerpina3mSerine protease inhibitor A3MIPI:IPI00135635ratio: 0.21
A3803 EF1D_MOUSEEef1dElongation factor 1-deltaIPI:IPI00118875ratio: 2.33
A8956 PRS10_MOUSEPsmc6, Sug226S protease regulatory subunit 10BIPI:IPI00125971ratio: 3.52
A7917 SYFB_MOUSEFarsb, Farsl, FarslbPhenylalanine--tRNA ligase beta subunitIPI:IPI00322828ratio: 2.63
A3942 STML2_MOUSEStoml2, Slp2Stomatin-like protein 2, mitochondrialIPI:IPI00115117ratio: 2.09
A051BXSRRT_MOUSESrrt, Ars2, Asr2Serrate RNA effector molecule homologIPI:IPI00266463ratio: 3.16
A0234 ARP3_MOUSEActr3, Arp3Actin-related protein 3IPI:IPI00115627ratio: 2.2
A9060XSORCN_MOUSESriSorcinIPI:IPI00318485ratio: 2.49
A9485 SRPRB_MOUSESrprbSignal recognition particle receptor subunit betaIPI:IPI00111271ratio: 3.59
A885AXPSPC1_MOUSEPspc1, Psp1Paraspeckle component 1IPI:IPI00321266ratio: 3.36
A7673 RENT1_MOUSEUpf1, Rent1Regulator of nonsense transcripts 1IPI:IPI00420949ratio: 2.16
A3611 RPN2_MOUSERpn2Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2IPI:IPI00475154ratio: 2.06
A7478 PPCE_MOUSEPrep, PepProlyl endopeptidaseIPI:IPI00132089ratio: 3.25
A8131 UBP7_MOUSEUsp7, HauspUbiquitin carboxyl-terminal hydrolase 7IPI:IPI00817018ratio: 2.4
A3945 SC23A_MOUSESec23a, Sec23, Sec23rProtein transport protein Sec23AIPI:IPI00123349ratio: 2.84
A3211 CKAP4_MOUSECkap4Cytoskeleton-associated protein 4IPI:IPI00223047ratio: 2.06
A4323 FKBP3_MOUSEFkbp3, Fkbp25Peptidyl-prolyl cis-trans isomerase FKBP3IPI:IPI00126000ratio: 2.34
A5669 ACO13_MOUSEAcot13, Them2Acyl-coenzyme A thioesterase 13IPI:IPI00132958ratio: 0.46
A834B ARF6_MOUSEArf6ADP-ribosylation factor 6IPI:IPI00221616ratio: 2.15
A8959 PRS6B_MOUSEPsmc4, Tbp726S protease regulatory subunit 6BIPI:IPI00828513ratio: 2.65
A3812 RL8_MOUSERpl860S ribosomal protein L8IPI:IPI00137787ratio: 2.34
A217C NDUS4_MOUSENdufs4NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrialIPI:IPI00229008ratio: 2.09
A376AXEIF3B_MOUSEEif3b, Eif3s9Eukaryotic translation initiation factor 3 subunit BIPI:IPI00229859ratio: 2.2
A7127XNCPR_MOUSEPorNADPH--cytochrome P450 reductaseIPI:IPI00621548ratio: 2.15
A8972XPSME2_MOUSEPsme2, Pa28b1, PSME2bProteasome activator complex subunit 2IPI:IPI00649986ratio: 0.4
A146BXU2AF2_MOUSEU2af2, U2af65Splicing factor U2AF 65 kDa subunitIPI:IPI00113746ratio: 0.42
A3662XPYC_MOUSEPc, PcxPyruvate carboxylase, mitochondrialIPI:IPI00114710ratio: 3.09
A9547 RL21_MOUSERpl2160S ribosomal protein L21IPI:IPI00315548ratio: 2.66
A8963 PSD11_MOUSEPsmd11Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 11IPI:IPI00222515ratio: 2.16
A0667XCDK5_MOUSECdk5, Cdkn5, Crk6Cyclin-dependent kinase 5IPI:IPI00309262ratio: 3.91
A7369 PGES2_MOUSEPtges2, Gbf1, Pges2Prostaglandin E synthase 2IPI:IPI00312174ratio: 2.48
A662A LYAR_MOUSELyarCell growth-regulating nucleolar proteinIPI:IPI00113232ratio: 2.12
A0960 ELOB_MOUSETceb2Transcription elongation factor B polypeptide 2IPI:IPI00131224ratio: 2.44
A793D PDDC1_MOUSEPddc1Parkinson disease 7 domain-containing protein 1IPI:IPI00224733ratio: 2.23
A6753 HTRA2_MOUSEHtra2, Omi, Prss25Serine protease HTRA2, mitochondrialIPI:IPI00275992ratio: 2.32
A6311XDHB8_MOUSEHsd17b8, H2-Ke6, Hke6Estradiol 17-beta-dehydrogenase 8IPI:IPI00115598ratio: 3.06
A540A HMGA1_MOUSEHmga1, Hmgi, HmgiyHigh mobility group protein HMG-I/HMG-YIPI:IPI00314240ratio: 2.12
A3887 NTRI_MOUSENtm, Hnt, NtNeurotriminIPI:IPI00417005ratio: 2.22
A933B CYGB_MOUSECygbCytoglobinIPI:IPI00109791ratio: 2.16
A3971 OPA1_MOUSEOpa1Dynamin-like 120 kDa protein, mitochondrialIPI:IPI00117657ratio: 3.9
A7915XSYEP_MOUSEEprs, QprsBifunctional glutamate/proline--tRNA ligaseIPI:IPI00339916ratio: 2.37
A3977XEMC2_MOUSEEmc2, Ttc35ER membrane protein complex subunit 2IPI:IPI00133612ratio: 10.21
A2102XCOPA_MOUSECopaCoatomer subunit alphaIPI:IPI00229834ratio: 3.45
A1164XIPO5_MOUSEIpo5, Kpnb3, Ranbp5Importin-5IPI:IPI00626994ratio: 3.93
A7774XSAHH2_MOUSEAhcyl1, IrbitPutative adenosylhomocysteinase 2IPI:IPI00162781ratio: 3.64
A2330 EEA1_MOUSEEea1Early endosome antigen 1IPI:IPI00453776ratio: 0.28
A6206XCPT2_MOUSECpt2, Cpt-2Carnitine O-palmitoyltransferase 2, mitochondrialIPI:IPI00648887ratio: 3.11
A7274 PADI2_MOUSEPadi2, Pdi, Pdi2Protein-arginine deiminase type-2IPI:IPI00123014ratio: 2.58
A784AXNONO_MOUSENonoNon-POU domain-containing octamer-binding proteinIPI:IPI00320016ratio: 0.4
MergeMe931 SBP2_MOUSESelenbp2, Lpsb2Selenium-binding protein 2IPI:IPI00323816ratio: 3.13
A8101XUBE2O_MOUSEUbe2oE2/E3 hybrid ubiquitin-protein ligase UBE2OIPI:IPI00453803ratio: 2.25
A3598 ALDH2_MOUSEAldh2, Ahd-1, Ahd1Aldehyde dehydrogenase, mitochondrialIPI:IPI00111218ratio: 4.18
A9651 RS5_MOUSERps540S ribosomal protein S5IPI:IPI00125521ratio: 2.71
A194C NDUA2_MOUSENdufa2NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2IPI:IPI00315302ratio: 2.14
A636A LC7L3_MOUSELuc7l3, CropLuc7-like protein 3IPI:IPI00649422ratio: 4.96
A7912 SYDC_MOUSEDarsAspartate--tRNA ligase, cytoplasmicIPI:IPI00122743ratio: 2.13
A4856XHSPB1_MOUSEHspb1, Hsp25, Hsp27Heat shock protein beta-1IPI:IPI00128522ratio: 0.34
A4034 VGLU1_MOUSESlc17a7, Bnpi, Vglut1Vesicular glutamate transporter 1IPI:IPI00109153ratio: 2.26
A9546 RL19_MOUSERpl1960S ribosomal protein L19IPI:IPI00122426ratio: 2.18
A0215 NEUM_MOUSEGap43, Basp2NeuromodulinIPI:IPI00128973ratio: 2.06
A9652 RS6_MOUSERps640S ribosomal protein S6IPI:IPI00113655ratio: 2.37
A4055XAN32B_MOUSEAnp32b, Pal31Acidic leucine-rich nuclear phosphoprotein 32 family member BIPI:IPI00831258ratio: 2.58
A4584XARL8B_MOUSEArl8b, Arl10c, Gie1ADP-ribosylation factor-like protein 8BIPI:IPI00133218ratio: 2.2
A203C NDUAD_MOUSENdufa13, Grim19NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13IPI:IPI00230715ratio: 2.68
A1711 AMRP_MOUSELrpap1Alpha-2-macroglobulin receptor-associated proteinIPI:IPI00469307ratio: 2.86
A968BXF120A_MOUSEFam120a, FAM120A, OssaConstitutive coactivator of PPAR-gamma-like protein 1IPI:IPI00830478ratio: 2.58
A5693 ACSL1_MOUSEAcsl1, Acsl2, Facl2Long-chain-fatty-acid--CoA ligase 1IPI:IPI00112549ratio: 2.11
A7187XNT5C_MOUSENt5c, Dnt15'(3')-deoxyribonucleotidase, cytosolic typeIPI:IPI00124639ratio: 2.77
A9136 UFC1_MOUSEUfc1Ubiquitin-fold modifier-conjugating enzyme 1IPI:IPI00132903ratio: 3.12
A7320 PCYOX_MOUSEPcyox1Prenylcysteine oxidaseIPI:IPI00460063ratio: 3.36
A9033 RPGP1_MOUSERap1gap, Rap1ga1Rap1 GTPase-activating protein 1IPI:IPI00649617ratio: 3.66
A613CXTIM50_MOUSETimm50, Tim50Mitochondrial import inner membrane translocase subunit TIM50IPI:IPI00111045ratio: 2.42
A9766XACINU_MOUSEAcin1, AcinusApoptotic chromatin condensation inducer in the nucleusIPI:IPI00121136ratio: 0.35
A7558XPUR9_MOUSEAtic, PurhBifunctional purine biosynthesis protein PURHIPI:IPI00330303ratio: 2.25
A3781XAIFM1_MOUSEAifm1, Aif, Pdcd8Apoptosis-inducing factor 1, mitochondrialIPI:IPI00129577ratio: 3.34
A024F DDX42_MOUSEDdx42ATP-dependent RNA helicase DDX42IPI:IPI00329839ratio: 7.82
A054CXKI21A_MOUSEKif21aKinesin-like protein KIF21AIPI:IPI00454081ratio: 2.04
A7925XSYMC_MOUSEMarsMethionine--tRNA ligase, cytoplasmicIPI:IPI00461469ratio: 2.83
A8966 PSMD7_MOUSEPsmd7, Mov-34, Mov3426S proteasome non-ATPase regulatory subunit 7IPI:IPI00114667ratio: 3.19
A3914XNIPS1_MOUSENipsnap1Protein NipSnap homolog 1IPI:IPI00115824ratio: 2.54
A1966XQ99L20Gstt3Glutathione S-transferase theta 3IPI:IPI00116236ratio: 2.24
A1978 GCYA3_MOUSEGucy1a3, Gucy1a1Guanylate cyclase soluble subunit alpha-3IPI:IPI00120015ratio: 3.33
A8651XAIMP1_MOUSEAimp1, Emap2, Scye1Aminoacyl tRNA synthase complex-interacting multifunctional protein 1IPI:IPI00132194ratio: 2.65
A8041 TRNT1_MOUSETrnt1CCA tRNA nucleotidyltransferase 1, mitochondrialIPI:IPI00187402ratio: 2.02
A3580XCYFP2_MOUSECyfip2, Pir121Cytoplasmic FMR1-interacting protein 2IPI:IPI00405625ratio: 3.04
A3472 CA2D2_MOUSECacna2d2Voltage-dependent calcium channel subunit alpha-2/delta-2IPI:IPI00111158ratio: 0.19
A7370 PGFS_MOUSEFam213bProstamide/prostaglandin F synthaseIPI:IPI00119094ratio: 3.31
A2573XRBM39_MOUSERbm39, Caper, Rnpc2RNA-binding protein 39IPI:IPI00223371ratio: 2.24
A7916 SYFA_MOUSEFarsa, FarslaPhenylalanine--tRNA ligase alpha subunitIPI:IPI00263874ratio: 2.37
A8139XUCHL3_MOUSEUchl3Ubiquitin carboxyl-terminal hydrolase isozyme L3IPI:IPI00311369ratio: 3.39
A1631XHPT_MOUSEHpHaptoglobinIPI:IPI00409148ratio: 0.09
A702B TMED9_MOUSETmed9Transmembrane emp24 domain-containing protein 9IPI:IPI00749993ratio: 20
A0222 GSK3B_MOUSEGsk3bGlycogen synthase kinase-3 betaIPI:IPI00125319ratio: 3.82
A5423 OCAD1_MOUSEOciad1, AsrijOCIA domain-containing protein 1IPI:IPI00133608ratio: 5.13
A771BXABC8B_MOUSEAbca8b, Abca8ATP-binding cassette sub-family A member 8-BIPI:IPI00170145ratio: 2.23
A5965 CAH3_MOUSECa3, Car3Carbonic anhydrase 3IPI:IPI00221890ratio: 0.43
A221C NECP1_MOUSENecap1Adaptin ear-binding coat-associated protein 1IPI:IPI00225533ratio: 4.02
A5213 TLN2_MOUSETln2Talin-2IPI:IPI00318182ratio: 0.48
A2554 RBM14_MOUSERbm14RNA-binding protein 14IPI:IPI00404707ratio: 2.68
A9641 RS24_MOUSERps2440S ribosomal protein S24IPI:IPI00465568ratio: 0.36
A250B ZN503_MOUSEZnf503, Nolz1, Zfp503Zinc finger protein 503IPI:IPI00626244ratio: 0.43
A679A MCTS1_MOUSEMcts1Malignant T-cell-amplified sequence 1IPI:IPI00626860ratio: 3.5
A1090 BORG4_MOUSECdc42ep4, Borg4, Cep4Cdc42 effector protein 4IPI:IPI00124906ratio: 13.09
A0391 ATP5J_MOUSEAtp5jATP synthase-coupling factor 6, mitochondrialIPI:IPI00125460ratio: 4.09
A9552 RL24_MOUSERpl2460S ribosomal protein L24IPI:IPI00134202ratio: 2.5
A8766XERLN2_MOUSEErlin2, Spfh2Erlin-2IPI:IPI00221540ratio: 3.44
A926B CX6B1_MOUSECox6b1, Cox6bCytochrome c oxidase subunit 6B1IPI:IPI00225390ratio: 3.02
A5133 SNTB1_MOUSESntb1, Snt2b1Beta-1-syntrophinIPI:IPI00230613ratio: 2.75
A046C IPO7_MOUSEIpo7, Ranbp7Importin-7IPI:IPI00331444ratio: 5.31
LOC637747   similar to Guanine nucleotide-binding protein G(i), alpha-2 subunitIPI:IPI00665576ratio: 0.47
A6892 LHPP_MOUSELhppPhospholysine phosphohistidine inorganic pyrophosphate phosphataseIPI:IPI00110351ratio: 2.49
A0306 KAP3_MOUSEPrkar2bcAMP-dependent protein kinase type II-beta regulatory subunitIPI:IPI00224570ratio: 2.15
A5953 C1TC_MOUSEMthfd1C-1-tetrahydrofolate synthase, cytoplasmicIPI:IPI00122862ratio: 4
A027CXHOOK3_MOUSEHook3Protein Hook homolog 3IPI:IPI00353927ratio: 2.41
A0093 PRPTZ_MOUSEPtprz1, RPTP-betaReceptor-type tyrosine-protein phosphatase zetaIPI:IPI00627008ratio: 0.25
A5737 ADPRH_MOUSEAdprh, Arh1[Protein ADP-ribosylarginine] hydrolaseIPI:IPI00111149ratio: 6.9
A7794 SERB_MOUSEPsphPhosphoserine phosphataseIPI:IPI00117146ratio: 2.16
A6198 CPNS1_MOUSECapns1, Capn4Calpain small subunit 1IPI:IPI00130992ratio: 3.17
A7139 NDUS8_MOUSENdufs8NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrialIPI:IPI00170093ratio: 2.03
A7495 PPT1_MOUSEPpt1, PptPalmitoyl-protein thioesterase 1IPI:IPI00331318ratio: 2.98
A4575XANXA4_MOUSEAnxa4, Anx4Annexin A4IPI:IPI00353727ratio: 2.11
A7850XSPCS3_MOUSESpcs3, Spc22Signal peptidase complex subunit 3IPI:IPI00410756ratio: 2.83
A4356 NPL4_MOUSENploc4, Npl4Nuclear protein localization protein 4 homologIPI:IPI00465884ratio: 2.6
A269F AIPL1_MOUSEAipl1Aryl-hydrocarbon-interacting protein-like 1IPI:IPI00884556ratio: 2.03
A0254XAP2M1_MOUSEAp2m1, Clapm1AP-2 complex subunit muIPI:IPI00116356ratio: 4.79
A4367 PIN1_MOUSEPin1Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1IPI:IPI00132093ratio: 2.12
A210C NDUB7_MOUSENdufb7NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7IPI:IPI00133215ratio: 4.21
A9545 RL18A_MOUSERpl18a60S ribosomal protein L18aIPI:IPI00162790ratio: 3.24
A1492XCO1A2_MOUSECol1a2, Cola2Collagen alpha-2(I) chainIPI:IPI00222188ratio: 0.46
A5561 MPU1_MOUSEMpdu1, Supl15hMannose-P-dolichol utilization defect 1 proteinIPI:IPI00331563ratio: 2.44
A2083 SNR40_MOUSESnrnp40, Wdr57U5 small nuclear ribonucleoprotein 40 kDa proteinIPI:IPI00461621ratio: 5.62
A5444 PTHB1_MOUSEBbs9, Pthb1Protein PTHB1IPI:IPI00752946ratio: 2.89
A6287 DDX6_MOUSEDdx6, Hlr2, RckProbable ATP-dependent RNA helicase DDX6IPI:IPI00109932ratio: 2.97
A587C SYT5_MOUSESyt5, Syt9Synaptotagmin-5IPI:IPI00127867ratio: 3.31
A6092 COMT_MOUSEComt, Comt1Catechol O-methyltransferaseIPI:IPI00132076ratio: 6.41
A784I TIPRL_MOUSETiprlTIP41-like proteinIPI:IPI00221741ratio: 2.23
A3957 MTX2_MOUSEMtx2Metaxin-2IPI:IPI00225254ratio: 2.6
A875B CHP1_MOUSEChp1, Chp, Sid470Calcineurin B homologous protein 1IPI:IPI00229680ratio: 2.53
A5573 OPA3_MOUSEOpa3Optic atrophy 3 protein homologIPI:IPI00312507ratio: 2.24
A3950XTOM70_MOUSETomm70a, D16Wsu109eMitochondrial import receptor subunit TOM70IPI:IPI00377728ratio: 2.29
A9451XPLXB2_MOUSEPlxnb2Plexin-B2IPI:IPI00405742ratio: 2.73
A0068 GBGT2_MOUSEGngt2, Gng8, Gngt8Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2IPI:IPI00468894ratio: 5.49
A3474 CA2D1_MOUSECacna2d1, Cacna2Voltage-dependent calcium channel subunit alpha-2/delta-1IPI:IPI00626793ratio: 2.29
A0122 CLCA_MOUSECltaClathrin light chain AIPI:IPI00648681ratio: 0.2
A4142 KPRA_MOUSEPrpsap1Phosphoribosyl pyrophosphate synthase-associated protein 1IPI:IPI00755389ratio: 3.43
A6521XFOLH1_MOUSEFolh1, Mopsm, Naalad1Glutamate carboxypeptidase 2IPI:IPI00785449ratio: 5.83
A074A RAB24_MOUSERab24Ras-related protein Rab-24IPI:IPI00116760ratio: 4.91
A8168 UGPA_MOUSEUgp2UTP--glucose-1-phosphate uridylyltransferaseIPI:IPI00131204ratio: 0.33
A4331 HS12B_MOUSEHspa12bHeat shock 70 kDa protein 12BIPI:IPI00224776ratio: 2.07
A475F BBS7_MOUSEBbs7, Bbs2l1Bardet-Biedl syndrome 7 protein homologIPI:IPI00229547ratio: 4.01
A7746 RPB7_MOUSEPolr2gDNA-directed RNA polymerase II subunit RPB7IPI:IPI00263106ratio: 0.35
A0026XHD_MOUSEHtt, Hd, HdhHuntingtinIPI:IPI00271166ratio: 5.67
A5937 BPHL_MOUSEBphlValacyclovir hydrolaseIPI:IPI00320462ratio: 0.49
A317C RAB21_MOUSERab21Ras-related protein Rab-21IPI:IPI00337980ratio: 3.58
A5208 TENS3_MOUSETns3, Tens1Tensin-3IPI:IPI00353237ratio: 2.48
A3582 ACACA_MOUSEAcaca, Acac, Gm738Acetyl-CoA carboxylase 1IPI:IPI00474783ratio: 4.24
A512C SNX1_MOUSESnx1Sorting nexin-1IPI:IPI00876001ratio: 6.53
A0495 TPPC4_MOUSETrappc4, SbdnTrafficking protein particle complex subunit 4IPI:IPI00112785ratio: 3.44
A894BXCOPB_MOUSECopb1, CopbCoatomer subunit betaIPI:IPI00120503ratio: 6.28
A5760 AKCL2_MOUSEAkr1e2, Akr1cl2, Akr1e11,5-anhydro-D-fructose reductaseIPI:IPI00121305ratio: 8.59
A1130XRPB1_MOUSEPolr2a, Rpii215, Rpo2-1DNA-directed RNA polymerase II subunit RPB1IPI:IPI00136207ratio: 5.74
A998A SF3A3_MOUSESf3a3, Sap61Splicing factor 3A subunit 3IPI:IPI00137848ratio: 2.87
A2114XSC31A_MOUSESec31aProtein transport protein Sec31AIPI:IPI00377592ratio: 3.36
A8958 PRS6A_MOUSEPsmc3, Tbp126S protease regulatory subunit 6AIPI:IPI00405114ratio: 2.33
A3990 CSKI1_MOUSECaskin1Caskin-1IPI:IPI00411109ratio: 0.45
A6588XGGCT_MOUSEGgctGamma-glutamylcyclotransferaseIPI:IPI00111004ratio: 3.23
A3997 TTYH1_MOUSETtyh1Protein tweety homolog 1IPI:IPI00113244ratio: 2.7
A7173 NPL_MOUSENplN-acetylneuraminate lyaseIPI:IPI00120989ratio: 8
A734A MUG1_MOUSEMug1, Mug-1Murinoglobulin-1IPI:IPI00123223ratio: 0.39
A3907 AP3M2_MOUSEAp3m2AP-3 complex subunit mu-2IPI:IPI00124286ratio: 3.1
A092CXLMAN1_MOUSELman1, Ergic53Protein ERGIC-53IPI:IPI00132475ratio: 3.01
A3993 ARM10_MOUSEArmc10Armadillo repeat-containing protein 10IPI:IPI00137460ratio: 2.42
A4392XTBCA_MOUSETbcaTubulin-specific chaperone AIPI:IPI00222972ratio: 2.81
A0063 GBG7_MOUSEGng7, Gngt7Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7IPI:IPI00230566ratio: 7.17
A8812 GLRX3_MOUSEGlrx3, Picot, Txnl2Glutaredoxin-3IPI:IPI00315550ratio: 6.42
A955BXEPN4_MOUSEClint1, Enth, Epn4Clathrin interactor 1IPI:IPI00400154ratio: 0.36
A261AXBTF3_MOUSEBtf3Transcription factor BTF3IPI:IPI00515257ratio: 0.41
A472F BBS2_MOUSEBbs2Bardet-Biedl syndrome 2 protein homologIPI:IPI00109070ratio: 20.6
A4372XPPIF_MOUSEPpifPeptidyl-prolyl cis-trans isomerase F, mitochondrialIPI:IPI00116228ratio: 5.78
A902C CA123_MOUSE UPF0587 protein C1orf123 homologIPI:IPI00120915ratio: 5.58
A835D PROSC_MOUSEProscProline synthase co-transcribed bacterial homolog proteinIPI:IPI00131548ratio: 2.12
A9851 CSN6_MOUSECops6, Csn6COP9 signalosome complex subunit 6IPI:IPI00131873ratio: 3.04
A1351XIF2G_MOUSEEif2s3xEukaryotic translation initiation factor 2 subunit 3, X-linkedIPI:IPI00230415ratio: 0.37
A382A EIF3I_MOUSEEif3i, Eif3s2, Trip1Eukaryotic translation initiation factor 3 subunit IIPI:IPI00269613ratio: 3.09
A7064 MSRA_MOUSEMsraMitochondrial peptide methionine sulfoxide reductaseIPI:IPI00331442ratio: 4.85
A044B SPT5H_MOUSESupt5h, Supt5Transcription elongation factor SPT5IPI:IPI00656221ratio: 3.35
A5932 BLVRB_MOUSEBlvrbFlavin reductase (NADPH)IPI:IPI00113996ratio: 4.08
A4271XATOX1_MOUSEAtox1Copper transport protein ATOX1IPI:IPI00117379ratio: 2.38
A6502 FBRL_MOUSEFblrRNA 2'-O-methyltransferase fibrillarinIPI:IPI00119581ratio: 7.32
A4010 WDR7_MOUSEWdr7, TragWD repeat-containing protein 7IPI:IPI00120637ratio: 5.74
A9865XDBLOH_MOUSEDiablo, SmacDiablo homolog, mitochondrialIPI:IPI00120937ratio: 3.76
A648H NXNL1_MOUSENxnl1, Rdcvf, Txnl6Nucleoredoxin-like protein 1IPI:IPI00121351ratio: 2.59
A7128XNDK3_MOUSENme3Nucleoside diphosphate kinase 3IPI:IPI00125450ratio: 13.13
A640I SZRD1_MOUSESzrd1SUZ domain-containing protein 1IPI:IPI00224792ratio: 5.3
A237A BAP18_MOUSEBap18Chromatin complexes subunit BAP18IPI:IPI00265101ratio: 4.91
A032I RAB28_MOUSERab28Ras-related protein Rab-28IPI:IPI00281538ratio: 3.26
A7395 PI42B_MOUSEPip4k2b, Pip5k2bPhosphatidylinositol 5-phosphate 4-kinase type-2 betaIPI:IPI00336318ratio: 2.64
A468E UBXN7_MOUSEUbxn7, Ubxd7UBX domain-containing protein 7IPI:IPI00467362ratio: 2.54
A3506 DCLK1_MOUSEDclk1, Dcamkl1, DclkSerine/threonine-protein kinase DCLK1IPI:IPI00468380ratio: 0.47
A698B TMCO1_MOUSETmco1Transmembrane and coiled-coil domain-containing protein 1IPI:IPI00121974ratio: 6.83
A8181 VAT1_MOUSEVat1, Vat-1Synaptic vesicle membrane protein VAT-1 homologIPI:IPI00126072ratio: 2.3
A9843 COMD1_MOUSECommd1, Murr1, U2/MUCOMM domain-containing protein 1IPI:IPI00128920ratio: 3.22
A3570 CSN3_MOUSECops3, Csn3COP9 signalosome complex subunit 3IPI:IPI00131870ratio: 6.4
A3634XCMTD1_MOUSEComtd1Catechol O-methyltransferase domain-containing protein 1IPI:IPI00222125ratio: 0.31
A8478 RGS6_MOUSERgs6Regulator of G-protein signaling 6IPI:IPI00265467ratio: 7.42
A9670 RT23_MOUSEMrps2328S ribosomal protein S23, mitochondrialIPI:IPI00284934ratio: 2.16
A6642 GPX1_MOUSEGpx1Glutathione peroxidase 1IPI:IPI00319652ratio: 10.6
A6091 COASY_MOUSECoasy, Ukr1Bifunctional coenzyme A synthaseIPI:IPI00322610ratio: 9.61
A6533 Q7TMC8Fuk, FuKL-fucose kinaseIPI:IPI00329962ratio: 0.23
A736AXMYCBP_MOUSEMycbp, Amy1C-Myc-binding proteinIPI:IPI00720194ratio: 2.21
A326A CSTF3_MOUSECstf3Cleavage stimulation factor subunit 3IPI:IPI00116929ratio: 2.19
A681CXVIGLN_MOUSEHdlbpVigilinIPI:IPI00123379ratio: 2.54
A1227 TEBP_MOUSEPtges3, Sid3177, TebpProstaglandin E synthase 3IPI:IPI00127989ratio: 0.44
A5485XSTRBP_MOUSEStrbp, SpnrSpermatid perinuclear RNA-binding proteinIPI:IPI00128254ratio: 2.46
A292A CHSP1_MOUSECarhsp1Calcium-regulated heat stable protein 1IPI:IPI00133349ratio: 0.36
A551E NDRG3_MOUSENdrg3, Ndr3Protein NDRG3IPI:IPI00136107ratio: 6.29
A0697 MP2K6_MOUSEMap2k6, Prkmk6, Sapkk3Dual specificity mitogen-activated protein kinase kinase 6IPI:IPI00137439ratio: 5.05
A5639 ABD12_MOUSEAbhd12Monoacylglycerol lipase ABHD12IPI:IPI00165731ratio: 2.72
A777D OTU6B_MOUSEOtud6bOTU domain-containing protein 6BIPI:IPI00169908ratio: 3.11
A9062 SPF30_MOUSESmndc1, Smnr, Spf30Survival of motor neuron-related-splicing factor 30IPI:IPI00221714ratio: 0.21
A309BXAPMAP_MOUSEApmapAdipocyte plasma membrane-associated proteinIPI:IPI00221998ratio: 3.97
A656E FTO_MOUSEFtoAlpha-ketoglutarate-dependent dioxygenase FTOIPI:IPI00280462ratio: 2.31
A032BXSNUT1_MOUSESart1, HafU4/U6.U5 tri-snRNP-associated protein 1IPI:IPI00323674ratio: 4.11
A3601 PCCA_MOUSEPccaPropionyl-CoA carboxylase alpha chain, mitochondrialIPI:IPI00330523ratio: 3.07
A6308 DHB4_MOUSEHsd17b4, Edh17b4Peroxisomal multifunctional enzyme type 2IPI:IPI00331628ratio: 6.4
A5794 AMPD2_MOUSEAmpd2AMP deaminase 2IPI:IPI00406639ratio: 3.8
A4023XMCU_MOUSEMcu, Ccdc109aCalcium uniporter protein, mitochondrialIPI:IPI00655156ratio: 3.03
A927A RCD1_MOUSERqcd1, Cnot9, Rcd1Cell differentiation protein RCD1 homologIPI:IPI00123602ratio: 6.61
A7858 SPSY_MOUSESmsSpermine synthaseIPI:IPI00124127ratio: 0.25
A599C THIOM_MOUSETxn2Thioredoxin, mitochondrialIPI:IPI00125652ratio: 0.39
A196G DUS3L_MOUSEDus3ltRNA-dihydrouridine(47) synthase [NAD(P)(+)]-likeIPI:IPI00129184ratio: 7.07
A113B Q9Z1A1TfgProtein TfgIPI:IPI00130013ratio: 3.59
A867C MPC2_MOUSEMpc2, Brp44Mitochondrial pyruvate carrier 2IPI:IPI00131896ratio: 0.46
A319A CRNL1_MOUSECrnkl1Crooked neck-like protein 1IPI:IPI00132376ratio: 4.29
A7444 PMM1_MOUSEPmm1Phosphomannomutase 1IPI:IPI00132682ratio: 2.02
A7019 MGLL_MOUSEMgllMonoglyceride lipaseIPI:IPI00132874ratio: 2.91
A3576 GDAP1_MOUSEGdap1Ganglioside-induced differentiation-associated protein 1IPI:IPI00134137ratio: 4.19
A2145 CORO7_MOUSECoro7Coronin-7IPI:IPI00135390ratio: 2.96
A0086XZO1_MOUSETjp1, Zo1Tight junction protein ZO-1IPI:IPI00135971ratio: 4.35
A7235 OPLA_MOUSEOplah5-oxoprolinaseIPI:IPI00169473ratio: 2.75
A7442 PMGE_MOUSEBpgmBisphosphoglycerate mutaseIPI:IPI00221663ratio: 4.5
A016AXNOMO1_MOUSENomo1Nodal modulator 1IPI:IPI00222429ratio: 5.6
A8639 2A5E_MOUSEPpp2r5eSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoformIPI:IPI00224697ratio: 2.1
A377A EIF3C_MOUSEEif3c, Eif3s8Eukaryotic translation initiation factor 3 subunit CIPI:IPI00321647ratio: 2.22
A3602XPCCB_MOUSEPccbPropionyl-CoA carboxylase beta chain, mitochondrialIPI:IPI00606510ratio: 8.13
A7126 NCOAT_MOUSEMgea5, HexcBifunctional protein NCOATIPI:IPI00655175ratio: 4.68
A7206 NUD16_MOUSENudt16U8 snoRNA-decapping enzymeIPI:IPI00109455ratio: 2.09
A8100 UBE2H_MOUSEUbe2hUbiquitin-conjugating enzyme E2 HIPI:IPI00125481ratio: 2.64
A675A MCA3_MOUSEEef1e1Eukaryotic translation elongation factor 1 epsilon-1IPI:IPI00133928ratio: 3.34
A548I SPS1_MOUSESephs1, Sps1Selenide, water dikinase 1IPI:IPI00221759ratio: 2.33
A3784 EXOG_MOUSEExog, Endogl1Nuclease EXOG, mitochondrialIPI:IPI00224069ratio: 2.51
A7664 RDH13_MOUSERdh13Retinol dehydrogenase 13IPI:IPI00229040ratio: 2.17
A511C SNP47_MOUSESnap47Synaptosomal-associated protein 47IPI:IPI00269408ratio: 3.38
A3750 Q8JZU2Slc25a1Protein Slc25a1IPI:IPI00276926ratio: 2.23
A093CXLMAN2_MOUSELman2Vesicular integral-membrane protein VIP36IPI:IPI00321634ratio: 0.33
A503KXABC8A_MOUSEAbca8aATP-binding cassette sub-family A member 8-AIPI:IPI00322575ratio: 2.93
A1944 FEN1_MOUSEFen1, Fen-1Flap endonuclease 1IPI:IPI00410836ratio: 3.03
A730K SG2B2_MOUSEScgb2b2, AbpeSecretoglobin family 2B member 2IPI:IPI00411016ratio: 0.29
A1856XMPP4_MOUSEMpp4, Dlg6MAGUK p55 subfamily member 4IPI:IPI00420402ratio: 5.51
A0273 NEB2_MOUSEPpp1r9bNeurabin-2IPI:IPI00420651ratio: 6.8
A0285 BSN_MOUSEBsnProtein bassoonIPI:IPI00461199ratio: 2.71
A5122 SEP15_MOUSE42248, 4224815 kDa selenoproteinIPI:IPI00112641ratio: 0.47
A9127 TRIM2_MOUSETrim2, NarfTripartite motif-containing protein 2IPI:IPI00113430ratio: 3.23
A8872 LTOR2_MOUSELamtor2, Mapbpip, Robld3Ragulator complex protein LAMTOR2IPI:IPI00119807ratio: 3.17
A6503 FCL_MOUSETsta3, P35b, Tstap35bGDP-L-fucose synthaseIPI:IPI00133690ratio: 7
A6605 GLPK_MOUSEGk, GykGlycerol kinaseIPI:IPI00135446ratio: 0.15
A7988 TIGAR_MOUSETigarFructose-2,6-bisphosphatase TIGARIPI:IPI00227451ratio: 2.88
A0698XZYX_MOUSEZyxZyxinIPI:IPI00228360ratio: 0.48
A8163XUFL1_MOUSEUfl1E3 UFM1-protein ligase 1IPI:IPI00317684ratio: 0.3
A601A IMPCT_MOUSEImpactProtein IMPACTIPI:IPI00319956ratio: 5.48
A4267XABCE1_MOUSEAbce1, RliATP-binding cassette sub-family E member 1IPI:IPI00322869ratio: 2.83
A669AXMBB1A_MOUSEMybbp1a, P160Myb-binding protein 1AIPI:IPI00331361ratio: 3.35
A7910 SYCC_MOUSECarsCysteine--tRNA ligase, cytoplasmicIPI:IPI00331422ratio: 3.31
A7726 RNZ2_MOUSEElac2Zinc phosphodiesterase ELAC protein 2IPI:IPI00400401ratio: 0.34
A0015XDLG1_MOUSEDlg1, Dlgh1, dlgh1Disks large homolog 1IPI:IPI00408668ratio: 2.4
A7086 CMTR1_MOUSECmtr1, Ftsjd2Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1IPI:IPI00459652ratio: 2.27
A5620X5NTC_MOUSENt5c2Cytosolic purine 5'-nucleotidaseIPI:IPI00111489ratio: 3.5
A125C MOT4_MOUSESlc16a3, Mct4Monocarboxylate transporter 4IPI:IPI00118910ratio: 0.46
A0472 PPR1B_MOUSEPpp1r1bProtein phosphatase 1 regulatory subunit 1BIPI:IPI00121349ratio: 2.32
A4845 GORS2_MOUSEGorasp2Golgi reassembly-stacking protein 2IPI:IPI00165716ratio: 6.68
A119C MMGT1_MOUSEMmgt1, Emc5, Tmem32Membrane magnesium transporter 1IPI:IPI00169845ratio: 3
A8904 NMRL1_MOUSENmral1NmrA-like family domain-containing protein 1IPI:IPI00169979ratio: 4
A6376 DTD2_MOUSEDtd2Probable D-tyrosyl-tRNA(Tyr) deacylase 2IPI:IPI00221814ratio: 2.74
A5496 TMM11_MOUSETmem11Transmembrane protein 11, mitochondrialIPI:IPI00222447ratio: 2.39
A6749 HSDL1_MOUSEHsdl1Inactive hydroxysteroid dehydrogenase-like protein 1IPI:IPI00225301ratio: 5.82
A6714 HEMH_MOUSEFechFerrochelatase, mitochondrialIPI:IPI00228343ratio: 2.71
A4102XCUL4A_MOUSECul4aCullin-4AIPI:IPI00321407ratio: 3.72
A8017XTPP2_MOUSETpp2Tripeptidyl-peptidase 2IPI:IPI00469194ratio: 2.02
A7240 OTU7B_MOUSEOtud7bOTU domain-containing protein 7BIPI:IPI00605489ratio: 0.19
A4114 ERLN1_MOUSEErlin1, Keo4, Spfh1Erlin-1IPI:IPI00762654ratio: 7.73
A8015 TPMT_MOUSETpmtThiopurine S-methyltransferaseIPI:IPI00115215ratio: 2.24
A1512 CO5A2_MOUSECol5a2Collagen alpha-2(V) chainIPI:IPI00121120ratio: 2.36
A400I SGTB_MOUSESgtbSmall glutamine-rich tetratricopeptide repeat-containing protein betaIPI:IPI00122527ratio: 7.09
A5690 ACSF2_MOUSEAcsf2Acyl-CoA synthetase family member 2, mitochondrialIPI:IPI00122633ratio: 2.11
A944B DYLT1_MOUSEDynlt1, Tctel1, Tctex-1Dynein light chain Tctex-type 1IPI:IPI00127431ratio: 0.48
A7262 P5CS_MOUSEAldh18a1, P5cs, PycsDelta-1-pyrroline-5-carboxylate synthaseIPI:IPI00129350ratio: 4.45
A177G DRG2_MOUSEDrg2Developmentally-regulated GTP-binding protein 2IPI:IPI00134820ratio: 2.31
A6076 CLYBL_MOUSEClybl, ClbCitrate lyase subunit beta-like protein, mitochondrialIPI:IPI00153903ratio: 0.34
A5065 Q8CFX3Pcdh1Protein Pcdh1IPI:IPI00154057ratio: 0.15
A427D FA49A_MOUSEFam49a, D12Ertd553eProtein FAM49AIPI:IPI00222044ratio: 6.8
A7922XSYIC_MOUSEIarsIsoleucine--tRNA ligase, cytoplasmicIPI:IPI00225201ratio: 2.33
A342J AASD1_MOUSEAarsd1, AlaxAlanyl-tRNA editing protein Aarsd1IPI:IPI00648549ratio: 2.07
EG627624   similar to leucine zipper transcription factor-like 1IPI:IPI00110027ratio: 5.83
A3620 AGK_MOUSEAgk, MulkAcylglycerol kinase, mitochondrialIPI:IPI00113606ratio: 3.59
A4128XGSH0_MOUSEGclm, GlclrGlutamate--cysteine ligase regulatory subunitIPI:IPI00114329ratio: 4.4
A467E UBXN6_MOUSEUbxn6, Ubxd1, Ubxdc2UBX domain-containing protein 6IPI:IPI00121151ratio: 2.79
A6255 DD19A_MOUSEDdx19a, Ddx19, Eif4a-rs1ATP-dependent RNA helicase DDX19AIPI:IPI00123651ratio: 3.9
A9057 SMAP1_MOUSESmap1Stromal membrane-associated protein 1IPI:IPI00127492ratio: 11.8
A9596 RM21_MOUSEMrpl2139S ribosomal protein L21, mitochondrialIPI:IPI00133965ratio: 2.57
A562A HTSF1_MOUSEHtatsf1HIV Tat-specific factor 1 homologIPI:IPI00221566ratio: 0.28
A472C G3X972Sec24cProtein Sec24cIPI:IPI00229483ratio: 2.97
F7134 Q8BML3Glt28d2Glycosyltransferase 28 domain containing 2IPI:IPI00309001ratio: 2.27
A380EXTCPR1_MOUSETecpr1Tectonin beta-propeller repeat-containing protein 1IPI:IPI00336291ratio: 3.17
A300K Q6SKR2N6amt1, Hemk2HemK methyltransferase family member 2, isoform CRA_cIPI:IPI00347285ratio: 3.79
A457A E9PVA8Gcn1l1GCN1 general control of amino-acid synthesis 1-like 1 (Yeast)IPI:IPI00457499ratio: 4.6
A177D ARPIN_MOUSEArpinArpinIPI:IPI00461011ratio: 3.79
F5674 EI3JB_MOUSEEif3j2, Eif3s1-2, Gm9781Eukaryotic translation initiation factor 3 subunit J-BIPI:IPI00471443ratio: 2.54
A6570 GANC_MOUSEGancNeutral alpha-glucosidase CIPI:IPI00623483ratio: 2.79
A273C OSBP1_MOUSEOsbpOxysterol-binding protein 1IPI:IPI00755161ratio: 0.44
A3932 PEX5R_MOUSEPex5l, Pex2, Pex5rPEX5-related proteinIPI:IPI00857176ratio: 3.24
A9673XRT26_MOUSEMrps2628S ribosomal protein S26, mitochondrialIPI:IPI00108194ratio: 4.39
A1724 SYJ2B_MOUSESynj2bp, Arip2, Omp25Synaptojanin-2-binding proteinIPI:IPI00109206ratio: 0.36
A458EXUBE4B_MOUSEUbe4b, Ufd2Ubiquitin conjugation factor E4 BIPI:IPI00112597ratio: 2.38
A4112 ERG28_MOUSEORF11Probable ergosterol biosynthetic protein 28IPI:IPI00112901ratio: 2.04
A5661 ACDSB_MOUSEAcadsbShort/branched chain specific acyl-CoA dehydrogenase, mitochondrialIPI:IPI00119842ratio: 2.13
A4088 CETN2_MOUSECetn2, CaltCentrin-2IPI:IPI00128741ratio: 4.8
A0332 ITSN1_MOUSEItsn1, Ese1, ItsnIntersectin-1IPI:IPI00129356ratio: 3.13
A0144 KPCE_MOUSEPrkce, Pkce, PkceaProtein kinase C epsilon typeIPI:IPI00130419ratio: 2.4
A383FXARP10_MOUSEActr10, Act11, Actr11Actin-related protein 10IPI:IPI00137206ratio: 6.33
A897BXCOPG1_MOUSECopg1, CopgCoatomer subunit gamma-1IPI:IPI00223437ratio: 2.5
A746D NHLC2_MOUSENhlrc2NHL repeat-containing protein 2IPI:IPI00227730ratio: 0.42
A1348 EI2BE_MOUSEEif2b5Translation initiation factor eIF-2B subunit epsilonIPI:IPI00261239ratio: 8.8
A5318 DRG1_MOUSEDrg1, Drg, Nedd-3Developmentally-regulated GTP-binding protein 1IPI:IPI00263313ratio: 5.13
A027F PAF1_MOUSEPaf1RNA polymerase II-associated factor 1 homologIPI:IPI00331654ratio: 4.33
A7566 PYR1_MOUSECadCAD proteinIPI:IPI00380280ratio: 0.42
A626C TMX4_MOUSETmx4, Txndc13Thioredoxin-related transmembrane protein 4IPI:IPI00453829ratio: 0.28
A3969 DCTN4_MOUSEDctn4Dynactin subunit 4IPI:IPI00556688ratio: 2.71
A714C XPO7_MOUSEXpo7, Ranbp16Exportin-7IPI:IPI00110049ratio: 5.78
A795D PDZ11_MOUSEPdzd11, Pdzk11PDZ domain-containing protein 11IPI:IPI00112676ratio: 0.36
A645C TS101_MOUSETsg101Tumor susceptibility gene 101 proteinIPI:IPI00117944ratio: 6.27
A5733XADK_MOUSEAdkAdenosine kinaseIPI:IPI00126940ratio: 2.83
A4000XEMC1_MOUSEEmc1ER membrane protein complex subunit 1IPI:IPI00226932ratio: 0.49
A9156 WDR48_MOUSEWdr48, Uaf1WD repeat-containing protein 48IPI:IPI00336198ratio: 5.27
A1101 ELP1_MOUSEIkbkap, Elp1, IkapElongator complex protein 1IPI:IPI00380780ratio: 2.87
A004GXCSN7B_MOUSECops7b, Csn7bCOP9 signalosome complex subunit 7bIPI:IPI00453769ratio: 4.6
A3739XS2535_MOUSESlc25a35Solute carrier family 25 member 35IPI:IPI00111884ratio: 2.46
A7738 RPAB3_MOUSEPolr2hDNA-directed RNA polymerases I, II, and III subunit RPABC3IPI:IPI00124284ratio: 2.74
A745A NCBP2_MOUSENcbp2, Cbp20Nuclear cap-binding protein subunit 2IPI:IPI00132019ratio: 0.15
A800F CGBP1_MOUSECggbp1CGG triplet repeat-binding protein 1IPI:IPI00221863ratio: 4.07
A485E WDR37_MOUSEWdr37WD repeat-containing protein 37IPI:IPI00387421ratio: 0.35
A046B SR140_MOUSEU2surp, Sr140U2 snRNP-associated SURP motif-containing proteinIPI:IPI00411097ratio: 4.25
A789A NOP58_MOUSENop58, Nol5Nucleolar protein 58IPI:IPI00463468ratio: 3.68
A5691XACSF3_MOUSEAcsf3Acyl-CoA synthetase family member 3, mitochondrialIPI:IPI00762636ratio: 0.22
A259D PBDC1_MOUSEPbdc1Protein PBDC1IPI:IPI00132352ratio: 6.47
A785G HOOK1_MOUSEHook1Protein Hook homolog 1IPI:IPI00170157ratio: 0.43
A5954 C1TM_MOUSEMthfd1lMonofunctional C1-tetrahydrofolate synthase, mitochondrialIPI:IPI00228113ratio: 4.71
A4182 PDS5B_MOUSEPds5b, Aprin, As3Sister chromatid cohesion protein PDS5 homolog BIPI:IPI00317401ratio: 0.33
A1043XRRP44_MOUSEDis3, Rrp44Exosome complex exonuclease RRP44IPI:IPI00407764ratio: 3.09
A3498 E9Q6P5Ttc7bProtein Ttc7bIPI:IPI00754876ratio: 2.29

Compile date 08-10-2018© iMODE-CKD consortium