CKDdb-logoCKDdb - Molecule ID BG486

geneACAA2
nameAcetyl-CoA acyltransferase 2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
THIM_HUMANP42765ENSG0000016731510449Hs.200136604770

Functions and classifications

GOC:mitochondrial inner membrane, C:mitochondrion, F:acetyl-CoA C-acyltransferase activity, P:cholesterol biosynthetic process, P:fatty acid metabolic process, P:negative regulation of mitochondrial outer membrane permeabilization, F:transferase activity, transferring acyl groups other than amino-acyl groups, P:acetyl-CoA metabolic process, P:fatty acid beta-oxidation, P:negative regulation of apoptotic process
UniProtAcetylation, Acyltransferase, Complete proteome, Direct protein sequencing, Fatty acid metabolism, Lipid metabolism, Mitochondrion, Phosphoprotein, Polymorphism, Reference proteome, Transferase, Transit peptide
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseBiomarkerFold change in diseaseP-valueDetectionMol. modificationValidationPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis) 3.480.000049RNA microarray  19698090
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis) 1.488.24E-06RNA microarray  20019191

Compile date 08-30-2016© iMODE-CKD consortium