CKDdb-logoCKDdb - Molecule ID B1982

geneCASP5, ICH3
nameCaspase-5 precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CASP5_HUMANP51878ENSG00000137757838Hs.213327602665

Functions and classifications

GOC:NLRP1 inflammasome complex, F:cysteine-type endopeptidase activity, F:cysteine-type peptidase activity, P:apoptotic process, P:cellular response to mechanical stimulus, P:proteolysis, P:regulation of apoptotic process, C:intracellular
UniProtAlternative initiation, Alternative splicing, Apoptosis, Complete proteome, Hydrolase, Polymorphism, Protease, Reference proteome, Thiol protease, Zymogen
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.426.19E-05RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium