CKDdb-logoCKDdb - Molecule ID B1281

geneATXN3L, ATX3L, MJDL
namePutative Ataxin-3-like protein
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGene
ATX3L_HUMANQ9H3M9ENSG0000012359492552Hs.382641

Functions and classifications

GOC:mitochondrial matrix, C:mitochondrial membrane, C:nuclear inclusion body, F:omega peptidase activity, F:RNA polymerase II regulatory region DNA binding, F:ubiquitin thiolesterase activity, F:ubiquitin-specific protease activity, P:cellular response to heat, P:cellular response to misfolded protein, P:exploration behavior, P:histone H3 deacetylation, P:misfolded or incompletely synthesized protein catabolic process, P:monoubiquitinated protein deubiquitination, P:proteasome-mediated ubiquitin-dependent protein catabolic process, P:protein deubiquitination, P:regulation of cell-substrate adhesion, P:regulation of transcription, DNA-templated, P:transcription, DNA-templated, P:metabolic process, C:nucleus, P:proteolysis, P:regulation of transcription, DNA-dependent, P:transcription, DNA-dependent
UniProt3D-structure, Complete proteome, Hydrolase, Nucleus, Polymorphism, Protease, Reference proteome, Repeat, Thiol protease, Transcription, Transcription regulation, Ubl conjugation pathway
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.20.00107RNA microarray19698090
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.291.72E-03RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium