CKDdb-logoCKDdb - Molecule ID B0124

geneAPOBEC3A
nameProbable C->U editing enzyme APOBEC-3A
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ABC3A_HUMANP31941ENSG00000128383100913187Hs.226307607109

Functions and classifications

GOC:cytoplasm, C:nucleus, F:cytidine deaminase activity, F:deoxycytidine deaminase activity, F:zinc ion binding, P:cellular response to xenobiotic stimulus, P:clearance of foreign intracellular DNA by conversion of DNA cytidine to uridine, P:defense response to virus, P:DNA cytosine deamination, P:DNA demethylation, P:innate immune response, P:negative regulation of transposition, P:negative regulation of viral genome replication, F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines, P:metabolic process, F:metal ion binding
UniProt3D-structure, Alternative initiation, Antiviral defense, Complete proteome, Cytoplasm, Direct protein sequencing, Hydrolase, Immunity, Innate immunity, Metal-binding, Nucleus, Polymorphism, Reference proteome, Zinc
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp23505438aHomo sapienskidneyproximal tubular cellsDiabetes (diabetic nephropathy)0.620cDNA microarray23505438
Exp23505438bHomo sapienskidneyproximal tubular cellsDiabetes (diabetic nephropathy)0.610.037cDNA microarray23505438

Compile date 08-10-2018© iMODE-CKD consortium