CKDdb-logoCKDdb - Molecule ID A9808

geneCard11
nameCaspase recruitment domain-containing protein 11
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CAR11_MOUSEQ8CIS0ENSMUSG00000036526108723Mm.46187606445, 607210, 615206

Functions and classifications

GOC:cytoplasm, C:immunological synapse, C:membrane raft, C:plasma membrane, C:T cell receptor complex, F:protein binding, P:positive regulation of B cell proliferation, P:positive regulation of cytokine production, P:positive regulation of I-kappaB kinase/NF-kappaB signaling, P:positive regulation of interleukin-2 biosynthetic process, P:positive regulation of NF-kappaB transcription factor activity, P:positive regulation of T cell activation, P:positive regulation of T cell proliferation, P:regulation of apoptotic process, P:regulation of B cell differentiation, P:regulation of immune response, P:regulation of T cell differentiation, P:signal transduction, P:T cell costimulation, P:thymic T cell selection, C:cytoplasm, C:immunological synapse, C:membrane raft, C:plasma membrane, C:T cell receptor complex, F:protein binding, P:positive regulation of B cell proliferation, P:positive regulation of cytokine production, P:positive regulation of I-kappaB kinase/NF-kappaB signaling, P:positive regulation of interleukin-2 biosynthetic process, P:positive regulation of NF-kappaB transcription factor activity, P:positive regulation of T cell activation, P:positive regulation of T cell proliferation, P:regulation of B cell differentiation, P:regulation of immune response, P:regulation of T cell differentiation, P:signal transduction, P:T cell costimulation, P:thymic T cell selection
UniProt3D-structure, Alternative splicing, Coiled coil, Complete proteome, Cytoplasm, Membrane, Phosphoprotein, Reference proteome
PADBunknown

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19836472Mus musculus kidneytubule cellsDiabetes (Diabetic Nephropathy)0.14 LC-MS/MS19836472
Exp21411733bMus musculus11macrophageF4/80hi cellsGlomerulonephritis (lupus nephritis)0.490cDNA microarray21411733
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI)0.460.000207RNA microarray24569379

Compile date 08-10-2018© iMODE-CKD consortium