CKDdb-logoCKDdb - Molecule ID A9807

geneAZU1
nameAzurocidin precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CAP7_HUMANP20160ENSG00000172232566Hs.72885162815

Functions and classifications

GOC:azurophil granule, C:extracellular region, F:heparin binding, F:serine-type endopeptidase activity, F:toxic substance binding, P:cellular extravasation, P:defense response to Gram-negative bacterium, P:glial cell migration, P:induction of positive chemotaxis, P:inflammatory response, P:macrophage chemotaxis, P:microglial cell activation, P:monocyte activation, P:negative regulation of apoptotic process, P:positive regulation of cell adhesion, P:positive regulation of fractalkine biosynthetic process, P:positive regulation of interleukin-1 beta biosynthetic process, P:positive regulation of MHC class II biosynthetic process, P:positive regulation of phagocytosis, P:positive regulation of tumor necrosis factor biosynthetic process, P:protein kinase C-activating G-protein coupled receptor signaling pathway, P:proteolysis, P:regulation of vascular permeability, F:toxin binding
UniProt3D-structure, Antibiotic, Antimicrobial, Chemotaxis, Complete proteome, Direct protein sequencing, Disulfide bond, Glycoprotein, Heparin-binding, Polymorphism, Reference proteome, Serine protease homolog, Signal
PADBsignalling

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.190.000718RNA microarray19698090

Compile date 08-10-2018© iMODE-CKD consortium