CKDdb-logoCKDdb - Molecule ID A9803

geneCASP8AP2, FLASH, RIP25
nameCASP8 associated protein 2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
C8AP2_HUMANQ9UKL3ENSP000003912109994Hs.558218606880

Functions and classifications

GOC:mitochondrion, C:PML body, F:cysteine-type endopeptidase activator activity involved in apoptotic process, F:death receptor binding, F:DNA binding, F:SUMO polymer binding, F:transcription corepressor activity, P:cell cycle, P:cellular response to mechanical stimulus, P:extrinsic apoptotic signaling pathway via death domain receptors, P:Fas signaling pathway, P:regulation of transcription, DNA-templated, P:transcription, DNA-templated, C:cytoplasm, C:nucleus, P:regulation of transcription, DNA-dependent, P:transcription, DNA-dependent
UniProt3D-structure, Acetylation, Activator, Apoptosis, Cell cycle, Complete proteome, Cytoplasm, Isopeptide bond, Mitochondrion, Nucleus, Phosphoprotein, Polymorphism, Reference proteome, Repressor, Transcription, Transcription regulation, Ubl conjugation
PADBTF: transcription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)3.83< 0.05RNA microarray21752957

Compile date 08-10-2018© iMODE-CKD consortium