CKDdb-logoCKDdb - Molecule ID A9802

geneBst2
nameBone marrow stromal antigen 2
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BST2_MOUSEQ8R2Q8ENSMUSG0000004671869550Mm.260325600534

Functions and classifications

GOC:anchored component of membrane, C:apical plasma membrane, C:cell surface, C:Golgi apparatus, C:integral component of membrane, C:late endosome, C:membrane raft, C:plasma membrane, F:metalloendopeptidase inhibitor activity, F:signal transducer activity, P:defense response to virus, P:innate immune response, P:negative regulation of cell growth, P:negative regulation of cell migration, P:negative regulation of endopeptidase activity, P:negative regulation of intracellular transport of viral material, P:negative regulation of plasmacytoid dendritic cell cytokine production, P:negative regulation of viral genome replication, P:positive regulation of I-kappaB kinase/NF-kappaB signaling, P:regulation of actin cytoskeleton organization, P:response to interferon-alpha, P:response to interferon-beta, P:response to interferon-gamma, P:response to virus, C:anchored to membrane, C:integral to membrane, P:negative regulation of egress of virus within host cell, P:positive regulation of I-kappaB kinase/NF-kappaB cascade
UniProt3D-structure, Cell membrane, Coiled coil, Complete proteome, Cytoplasm, Disulfide bond, Endosome, Glycoprotein, Golgi apparatus, GPI-anchor, Immunity, Innate immunity, Lipoprotein, Membrane, Reference proteome, Signal-anchor, Transmembrane, Transmembrane helix
PADBtransmembrane

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)4.82< 0.05RNA microarray21752957
Exp23757392aRattus norvegicus17kidneywholeDiabetes (diabetic nephropathy)0.38< 0.05RNA-seq23757392
Exp23757392bRattus norvegicus13kidneywholeDiabetes (diabetic nephropathy)0.39< 0.05RNA-seq23757392
Exp24262798aMus musculus kidneypodocytesnephropathies (collagen IV nephropathies)19.433.37E-07RNA microarray24262798
Exp24262798bMus musculus kidneypodocytesnephropathies (collagen IV nephropathies)19.433.37E-07RNA microarray24262798

Compile date 08-10-2018© iMODE-CKD consortium