CKDdb-logoCKDdb - Molecule ID A9801

geneBPI
nameBactericidal permeability-increasing protein precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BPI_HUMANP17213ENSG00000101425671Hs.529019109195

Functions and classifications

GOC:cytoplasm, C:extracellular region, C:integral component of plasma membrane, F:lipopolysaccharide binding, P:defense response to bacterium, P:immune response, P:negative regulation of interleukin-6 production, P:negative regulation of interleukin-8 production, P:negative regulation of macrophage activation, P:negative regulation of tumor necrosis factor production, F:lipid binding, C:integral to plasma membrane, F:Gram-negative bacterial cell surface binding
UniProt3D-structure, Antibiotic, Antimicrobial, Complete proteome, Direct protein sequencing, Disulfide bond, Glycoprotein, Membrane, Polymorphism, Reference proteome, Secreted, Signal
PADBsignalling

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.350.0435RNA microarray19698090
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.23< 0.05RNA microarray21752957

Compile date 08-10-2018© iMODE-CKD consortium