CKDdb-logoCKDdb - Molecule ID A9766

geneAcin1, Acinus, mKIAA0670
nameApoptotic chromatin condensation inducer in the nucleus
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGene
ACINU_MOUSEQ9JIX8ENSMUSG0000002218556215Mm.297078

Functions and classifications

GOC:ASAP complex, C:cytoplasm, C:exon-exon junction complex, C:nuclear speck, C:nucleolus, C:nucleus, F:nucleic acid binding, F:nucleotide binding, P:apoptotic chromosome condensation, P:apoptotic process, P:erythrocyte differentiation, P:mRNA processing, P:negative regulation of mRNA splicing, via spliceosome, P:positive regulation of apoptotic process, P:positive regulation of monocyte differentiation, P:RNA splicing, C:nucleolus, C:nucleus, F:nucleic acid binding, F:nucleotide binding, P:apoptotic process, C:nucleolus, C:nucleus, P:apoptotic process, C:nucleolus, C:nucleus, P:apoptotic process, C:nucleolus, C:nucleus, F:nucleic acid binding, F:nucleotide binding, P:apoptotic process, C:nucleolus, C:nucleus, F:nucleic acid binding, F:nucleotide binding, P:apoptotic process, C:nucleolus, C:nucleus, F:nucleic acid binding, F:nucleotide binding, P:apoptotic process, C:ASAP complex, C:cytoplasm, C:exon-exon junction complex, C:nuclear speck, C:nucleolus, C:nucleus, P:apoptotic chromosome condensation, P:apoptotic process, P:erythrocyte differentiation, P:negative regulation of mRNA splicing, via spliceosome, P:positive regulation of apoptotic process, P:positive regulation of monocyte differentiation, C:nucleolus, C:nucleus, F:nucleic acid binding, F:nucleotide binding, P:apoptotic process, C:nucleolus, C:nucleus, F:nucleic acid binding, P:apoptotic process, , , C:nucleolus, C:nucleus, P:apoptotic process
UniProtAcetylation, Alternative splicing, Apoptosis, Complete proteome, Isopeptide bond, Methylation, mRNA processing, mRNA splicing, Nucleus, Phosphoprotein, Reference proteome, Ubl conjugation, Complete proteome, Reference proteome, Complete proteome, Reference proteome, Complete proteome, Reference proteome, Complete proteome, Reference proteome, , , , , , , , Complete proteome, Reference proteome
PADBsignalling

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseBiomarkerFold change in diseaseP-valueDetectionMol. modificationValidationPubMed/DOI
Exp19845401Mus musculus32eyesretinaDiabetes (diabetic retinopathy) 0.35< 0.05LC-MS/MS  19845401
Exp20940332Mus musculus kidneycollecting duct cellsVasopressine_induced (Vasopressine in vitro model) 0.76< 0.05LC-MS/MS  20940332

Compile date 08-30-2016© iMODE-CKD consortium