CKDdb-logoCKDdb - Molecule ID A931K

geneAMELX, AMG, AMGX
nameAmelogenin
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AMELX_HUMANQ99217ENSG00000125363265Hs.654436300391, 301200

Functions and classifications

GOC:cell surface, C:proteinaceous extracellular matrix, F:growth factor activity, F:hydroxyapatite binding, F:identical protein binding, F:structural constituent of tooth enamel, P:cell adhesion, P:cell proliferation, P:chondrocyte differentiation, P:enamel mineralization, P:epithelial to mesenchymal transition, P:ion homeostasis, P:osteoblast differentiation, P:positive regulation of collagen biosynthetic process, P:positive regulation of tooth mineralization, P:signal transduction, P:multicellular organismal development, C:extracellular matrix part, F:cell surface binding
UniProtAlternative splicing, Amelogenesis imperfecta, Biomineralization, Complete proteome, Direct protein sequencing, Disease mutation, Extracellular matrix, Phosphoprotein, Reference proteome, Repeat, Secreted, Signal
PADBCell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.180.00000904RNA microarray19698090
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.363.43E-03RNA microarray26317775
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.190.013999RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium