CKDdb-logoCKDdb - Molecule ID A9255

geneBtla
nameB- and T-lymphocyte attenuator
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BTLA_MOUSEQ7TSA3ENSMUSG00000052013208154Mm.38199607925

Functions and classifications

GOC:external side of plasma membrane, C:integral component of plasma membrane, F:protein binding, F:receptor activity, P:cell surface receptor signaling pathway, P:immune response-regulating cell surface receptor signaling pathway, P:immune system process, P:negative regulation of alpha-beta T cell proliferation, P:negative regulation of B cell proliferation, P:negative regulation of T cell proliferation, C:external side of plasma membrane, C:integral component of plasma membrane, F:protein binding, F:receptor activity, P:cell surface receptor signaling pathway, P:immune response-regulating cell surface receptor signaling pathway, P:negative regulation of alpha-beta T cell proliferation, P:negative regulation of B cell proliferation, P:negative regulation of T cell proliferation, C:external side of plasma membrane, C:integral component of plasma membrane, F:protein binding, F:receptor activity, P:cell surface receptor signaling pathway, P:immune response-regulating cell surface receptor signaling pathway, P:negative regulation of alpha-beta T cell proliferation, P:negative regulation of B cell proliferation, P:negative regulation of T cell proliferation
UniProt3D-structure, Adaptive immunity, Alternative splicing, Complete proteome, Disulfide bond, Glycoprotein, Immunity, Immunoglobulin domain, Membrane, Phosphoprotein, Receptor, Reference proteome, Signal, Transmembrane, Transmembrane helix
PADBtransmembrane

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp23757392aRattus norvegicus17kidneywholeDiabetes (diabetic nephropathy)2.51< 0.05RNA-seq23757392
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI)0.380.0000077RNA microarray24569379
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.150.013999RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium