CKDdb-logoCKDdb - Molecule ID A9251

geneASGR1, CLEC4H1
nameAsialoglycoprotein receptor 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ASGR1_HUMANP07306ENSG00000141505432Hs.12056108360

Functions and classifications

GOC:extracellular region, C:integral component of plasma membrane, F:asialoglycoprotein receptor activity, F:carbohydrate binding, F:metal ion binding, P:cellular response to extracellular stimulus, P:receptor-mediated endocytosis, C:integral to plasma membrane
UniProt3D-structure, Alternative splicing, Calcium, Coiled coil, Complete proteome, Disulfide bond, Endocytosis, Glycoprotein, Lectin, Lipoprotein, Membrane, Metal-binding, Palmitate, Phosphoprotein, Receptor, Reference proteome, Secreted, Signal-anchor, Transmembrane, Transmembrane helix
PADBtransport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)3.130.000567RNA microarray19698090
Exp23757392aRattus norvegicus17kidneywholeDiabetes (diabetic nephropathy)0.36< 0.05RNA-seq23757392
Exp23757392bRattus norvegicus13kidneywholeDiabetes (diabetic nephropathy)0.44< 0.05RNA-seq23757392
Exp25770168Homo sapiens17bloodmononuclear cellsGlomerulonephritis (IgA nephropathy)5.660.004RNA microarray25770168

Compile date 08-10-2018© iMODE-CKD consortium