CKDdb-logoCKDdb - Molecule ID A9250

geneAPLNR, AGTRL1, APJ
nameApelin receptor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
APJ_HUMANP35414ENSG00000134817187Hs.438311600052

Functions and classifications

GOC:integral component of plasma membrane, F:G-protein coupled receptor activity, C:integral component of membrane, C:cytoplasmic vesicle, C:integral to plasma membrane, C:nucleus, P:regulation of body fluid levels, C:integral to membrane
UniProt3D-structure, Cell membrane, Complete proteome, G-protein coupled receptor, Glycoprotein, Membrane, Polymorphism, Receptor, Reference proteome, Transducer, Transmembrane, Transmembrane helix
PADBreceptor

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19099603cMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.280cDNA microarray19099603
Exp19099603dMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.360.02cDNA microarray19099603
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.470.0277RNA microarray19698090
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)2.910.000486783RNA microarray20019191
Exp20706631Mus musculus6kidneyglomerular capillary endothelial cellDiabetes (diabetic nephropathy)0.13< 0.05RNA microarray20706631
Exp23757392aRattus norvegicus17kidneywholeDiabetes (diabetic nephropathy)2.27< 0.05RNA-seq23757392
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI)0.150.000000682RNA microarray24569379

Compile date 08-10-2018© iMODE-CKD consortium