CKDdb-logoCKDdb - Molecule ID A8703

geneCasp12
nameCaspase-12
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CASPC_MOUSEO08736ENSMUSG0000002588712364Mm.42163608633

Functions and classifications

GOC:cytoplasm, C:endoplasmic reticulum, F:cysteine-type endopeptidase activity, F:protein binding, P:apoptotic process, P:endoplasmic reticulum unfolded protein response, P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, P:regulation of apoptotic process, C:cytoplasm, C:endoplasmic reticulum, F:cysteine-type endopeptidase activity, F:protein binding, P:apoptotic process, P:endoplasmic reticulum unfolded protein response, P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, C:cytoplasm, C:endoplasmic reticulum, F:cysteine-type endopeptidase activity, F:protein binding, P:apoptotic process, P:endoplasmic reticulum unfolded protein response, P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, P:regulation of apoptotic process, C:cytoplasm, C:endoplasmic reticulum, F:cysteine-type endopeptidase activity, F:protein binding, P:apoptotic process, P:endoplasmic reticulum unfolded protein response, P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, P:regulation of apoptotic process, C:cytoplasm, C:endoplasmic reticulum, F:cysteine-type endopeptidase activity, F:protein binding, P:apoptotic process, P:endoplasmic reticulum unfolded protein response, P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, P:regulation of apoptotic process, C:cytoplasm, C:endoplasmic reticulum, F:cysteine-type endopeptidase activity, F:protein binding, P:apoptotic process, P:endoplasmic reticulum unfolded protein response, P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, C:cytoplasm, C:endoplasmic reticulum, F:cysteine-type endopeptidase activity, F:protein binding, P:apoptotic process, P:endoplasmic reticulum unfolded protein response, P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, P:regulation of apoptotic process
UniProtApoptosis, Complete proteome, Hydrolase, Protease, Reference proteome, Thiol protease, Zymogen
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19099603cMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)2.950.04cDNA microarray19099603
Exp19099603dMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)3.210.01cDNA microarray19099603
Exp20813037cRattus norvegicus6kidneywholePolycystic_Kidney_Disease (polycystic kidney disease)2.142.42E-08RNA microarray20813037
Exp23757392aRattus norvegicus17kidneywholeDiabetes (diabetic nephropathy)2.7< 0.05RNA-seq23757392
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI)0.280.000261RNA microarray24569379

Compile date 08-10-2018© iMODE-CKD consortium