CKDdb-logoCKDdb - Molecule ID A8699

geneCARD9
nameCaspase recruitment domain-containing protein 9
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CARD9_HUMANQ9H257ENSG0000018779664170Hs.694071212050, 607212

Functions and classifications

GOC:cytoplasm, P:defense response to Gram-positive bacterium, P:defense response to virus, P:innate immune response, P:nucleotide-binding oligomerization domain containing signaling pathway, P:positive regulation of I-kappaB kinase/NF-kappaB signaling, P:positive regulation of interleukin-6 production, P:positive regulation of JNK cascade, P:positive regulation of tumor necrosis factor production, P:regulation of apoptotic process, P:regulation of interleukin-2 biosynthetic process, P:regulation of interleukin-6 biosynthetic process, P:regulation of tumor necrosis factor biosynthetic process, P:response to drug, P:response to exogenous dsRNA, P:response to fungus, P:response to muramyl dipeptide, P:response to peptidoglycan, P:I-kappaB kinase/NF-kappaB cascade, P:positive regulation of I-kappaB kinase/NF-kappaB cascade
UniProtAlternative splicing, Coiled coil, Complete proteome, Cytoplasm, Phosphoprotein, Polymorphism, Reference proteome
PADBunknown

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.490.0101RNA microarray19698090
Exp23757392aRattus norvegicus17kidneywholeDiabetes (diabetic nephropathy)2.56< 0.05RNA-seq23757392
Exp24172336Mus musculus6kidneycortexAKI (AKI)3.80.003196058LC-MS/MS24172336

Compile date 08-10-2018© iMODE-CKD consortium