CKDdb-logoCKDdb - Molecule ID A8698

geneCARD14, CARMA2
nameCaspase recruitment domain-containing protein 14
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CAR14_HUMANQ9BXL6ENSG0000014152779092Hs.675480173200, 602723, 607211

Functions and classifications

GOC:aggresome, C:cytoplasm, C:plasma membrane, P:activation of NF-kappaB-inducing kinase activity, P:apoptotic process, P:negative regulation of apoptotic process, P:positive regulation of NF-kappaB transcription factor activity, P:tumor necrosis factor-mediated signaling pathway, P:regulation of apoptotic process, C:intracellular
UniProtAlternative splicing, Apoptosis, Coiled coil, Complete proteome, Cytoplasm, Disease mutation, Phosphoprotein, Polymorphism, Reference proteome
PADBsignalling

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp17579666cMus musculus6 to 12kidneywholeremnant_kidney_model (remnant kidney model)5.160.05RNA microarray17579666
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.20.000154RNA microarray19698090

Compile date 08-10-2018© iMODE-CKD consortium