CKDdb-logoCKDdb - Molecule ID A8681

geneATPIF1, ATPI, ASI
nameATPase inhibitor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ATIF1_HUMANQ9UII2ENSG0000013077093974Hs.744914614981

Functions and classifications

GOC:cell surface, C:mitochondrion, F:angiostatin binding, F:ATPase binding, F:ATPase inhibitor activity, F:calmodulin binding, F:protein homodimerization activity, P:angiogenesis, P:erythrocyte differentiation, P:generation of precursor metabolites and energy, P:heme biosynthetic process, P:negative regulation of endothelial cell proliferation, P:negative regulation of hydrolase activity, P:negative regulation of nucleotide metabolic process, P:positive regulation of mitochondrial outer membrane permeabilization, P:protein homotetramerization, P:reactive oxygen species metabolic process, P:regulation of apoptotic process, F:enzyme inhibitor activity, P:negative regulation of catalytic activity
UniProtAlternative splicing, Coiled coil, Complete proteome, Direct protein sequencing, Mitochondrion, Reference proteome, Transit peptide
PADBunknown

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp23809614aHomo sapiens83bloodwholeChronic_Renal_Insufficiency (End-stage renal failure)0.172.92E-16RNA microarray23809614
Exp23809614bHomo sapiens32bloodwholeChronic_Renal_Insufficiency (End-stage renal failure)0.195.36E-09RNA microarray23809614

Compile date 08-10-2018© iMODE-CKD consortium