CKDdb-logoCKDdb - Molecule ID A8669

geneARHGEF11
nameRho guanine nucleotide exchange factor 11
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ARHGB_HUMANO15085ENSG000001326949826Hs.516954605708

Functions and classifications

GOC:cytosol, C:membrane, F:G-protein coupled receptor binding, F:GTPase activator activity, F:Rho guanyl-nucleotide exchange factor activity, P:actin cytoskeleton organization, P:apoptotic signaling pathway, P:axon guidance, P:cytokinesis, P:establishment of cell polarity, P:G-protein coupled receptor signaling pathway, P:neurotrophin TRK receptor signaling pathway, P:positive regulation of apoptotic process, P:positive regulation of GTPase activity, P:positive regulation of transcription, DNA-templated, P:regulation of cell growth, P:Rho protein signal transduction, P:striated muscle contraction, P:termination of G-protein coupled receptor signaling pathway, P:regulation of Rho GTPase activity, F:phospholipid binding, P:apoptotic process, P:cellular component movement, P:nerve growth factor receptor signaling pathway, P:positive regulation of transcription, DNA-dependent, P:regulation of Rho protein signal transduction, P:regulation of small GTPase mediated signal transduction, C:intracellular
UniProt3D-structure, Alternative splicing, Coiled coil, Complete proteome, Cytoplasm, GTPase activation, Guanine-nucleotide releasing factor, Membrane, Phosphoprotein, Polymorphism, Reference proteome
PADBmodulator, regulator

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.470.00119RNA microarray19698090

Compile date 08-10-2018© iMODE-CKD consortium