CKDdb-logoCKDdb - Molecule ID A8648

geneAGAP3, CENTG3, MRIP-1
nameCentaurin gamma 3
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGene
AGAP3_HUMANQ96P47ENSG00000133612116988Hs.647075

Functions and classifications

GOC:cell periphery, C:cytoplasm, C:membrane, C:nucleus, F:ARF GTPase activator activity, F:GTP binding, F:GTPase activity, F:zinc ion binding, P:cellular response to reactive oxygen species, P:positive regulation of GTPase activity, P:proteasome-mediated ubiquitin-dependent protein catabolic process, P:protein import into nucleus, translocation, P:regulation of ARF GTPase activity, P:small GTPase mediated signal transduction, C:intracellular, P:small GTPase mediated signal transduction, C:clathrin adaptor complex, P:intracellular protein transport, P:vesicle-mediated transport, P:signal transduction, P:signal transduction", P:GTP catabolic process, P:regulation of ARF GTPase activity", F:metal ion binding, F:phospholipid binding, P:proteasomal ubiquitin-dependent protein catabolic process
UniProt3D-structure, Alternative splicing, ANK repeat, Complete proteome, Cytoplasm, GTP-binding, GTPase activation, Metal-binding, Nucleotide-binding, Phosphoprotein, Reference proteome, Repeat, Zinc, Zinc-finger, Membrane, Protein transport, Transport
PADBTF: transcription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.463.23E-05RNA microarray26317775
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)9.270.00656RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium