CKDdb-logoCKDdb - Molecule ID A8437

geneCCAR2, DBC1, DBC-1
nameProtein KIAA1967
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CCAR2_HUMANQ8N163ENSG0000015894157805Hs.744848607359

Functions and classifications

GOC:DBIRD complex, C:mitochondrial matrix, C:nuclear chromatin, F:enzyme inhibitor activity, F:RNA polymerase II core binding, P:cell cycle, P:cellular response to DNA damage stimulus, P:mitochondrial fragmentation involved in apoptotic process, P:mRNA processing, P:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage, P:positive regulation of apoptotic process, P:positive regulation of DNA damage checkpoint, P:regulation of DNA-templated transcription, elongation, P:response to UV, P:RNA splicing, P:apoptotic process, C:nucleus, P:regulation of DNA-dependent transcription, elongation
UniProtAcetylation, Alternative splicing, Apoptosis, Cell cycle, Coiled coil, Complete proteome, DNA damage, Metalloenzyme inhibitor, mRNA processing, mRNA splicing, Nucleus, Phosphoprotein, Reference proteome
PADBinhibitor (protease, kinase, other enzymes, pathways)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.270.00268RNA microarray19698090
Exp24172336Mus musculus6kidneycortexAKI (AKI)3.30.022973399LC-MS/MS24172336

Compile date 08-10-2018© iMODE-CKD consortium