CKDdb-logoCKDdb - Molecule ID A8389

geneCARD18, ICEBERG, UNQ5804/PRO19611
nameCaspase recruitment domain-containing protein 18
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CAR18_HUMANP57730ENSG0000025550159082Hs.56279605354

Functions and classifications

GOC:intracellular, F:cysteine-type endopeptidase inhibitor activity, P:inflammatory response, P:negative regulation of endopeptidase activity, P:regulation of apoptotic process
UniProt3D-structure, Complete proteome, Protease inhibitor, Reference proteome, Thiol protease inhibitor
PADBINH: inhibitor (protease, kinase, other enzymes, pathways)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.281.16E-03RNA microarray26317775
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.150.014678RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium