CKDdb-logoCKDdb - Molecule ID A8376

geneA1i3, Mug1
nameAlpha-1-inhibitor 3
speciesRattus norvegicus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGene
A1I3_RATP14046ENSRNOG00000037188297568Rn.109457

Functions and classifications

GOC:extracellular space, F:peptidase inhibitor activity, F:serine-type endopeptidase inhibitor activity, P:inflammatory response, P:negative regulation of endopeptidase activity
UniProtBait region, Complete proteome, Direct protein sequencing, Disulfide bond, Glycoprotein, Protease inhibitor, Reference proteome, Secreted, Serine protease inhibitor, Signal, Thioester bond
PADBinhibitor (protease, kinase, other enzymes, pathways)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseBiomarkerFold change in diseaseP-valueDetectionMol. modificationValidationPubMed/DOI
Exp21544065aRattus norvegicus17kidney Diabetes (diabetic nephropathy in T1D) 1.250.003MALDI-TOF/TOF  21544065
Exp21544065bRattus norvegicus17kidney Diabetes (diabetic nephropathy in T1D) 0.48< 0.001MALDI-TOF/TOF  21544065
Exp21544065cRattus norvegicus17kidney Diabetes (diabetic nephropathy in T1D) 0.18< 0.001MALDI-TOF/TOF  21544065
Exp23344851Rattus norvegicus14urineexosomeDiabetes (diabetic nephropathy) 1.38 nLC-ESI-UHR-QToF-MS/MS  23344851
Exp24497609Rattus norvegicus kidneyglomeruliPuromycin_induced (Puromycin nephropathy model) 5.66< 0.05LC-MS/MS  24497609
Exp24761003bRattus norvegicus18kidneymedullaureteral_obstruction (obstructive uropathy) 0.85< 0.05LC-MS/MS  24761003
Exp24761003cRattus norvegicus18kidneymedullaureteral_obstruction (obstructive uropathy) 0.59< 0.05LC-MS/MS  24761003

Compile date 08-30-2016© iMODE-CKD consortium